Uncle Zhou of Linyi, Shandong, is a long-lived old man who just passed away in October this year and walked very calmly without pain. But many people do not know that he has been taking antihypertensive drugs for 30 years, and in the 10 years of taking antihypertensive drugs, side effects have occurred continuously, causing Uncle Zhou to want to give up.
Eating antihypertensive drugs has side effects, do not take antihypertensive drugs, you will be damaged by high blood pressure, including the heart, kidneys, brain, etc., for a long time, there may be breathing difficulties, heart failure, renal function loss, kidney failure and stroke, seriously endangering physical health. How did Uncle Zhou overcome it? What is his history of taking medicine?
Taking medicine for 30 years, in the surrounding hypertensive population, it is a long time, but it is not smooth sailing! Because When Uncle Zhou found high blood pressure at the age of 65, he was already moderate hypertension and had to take medication to control blood pressure.
Because of the need to eat for a long time, So Uncle Zhou considered the cost of medication and chose nifedipine tablets, only 5 yuan, 100 tablets, very cheap and affordable. What makes Uncle Zhou even happier is that it can really lower blood pressure, and after eating it for only one day, blood pressure has come down. Therefore, Uncle Zhou has great trust in this medicine, after all, it will have an immediate effect!
Nifedipine tablets are the first generation of diplate drugs, short-acting and low bioavailability, so it will lead to large fluctuations in blood concentrations, long-term use is prone to vasodilation and sympathetic nervous system activation, easy to cause reflex tachycardia, headache and palpitations and other side effects. However, for patients who use it in the early stage, it is generally tolerated, so Uncle Zhou did not find a problem.
But after 6 months, Uncle Zhou often felt that he had a headache, so he went to the hospital to check it out, it turned out that his blood pressure was very unstable, which was also the shortcoming of short-acting nifedipine, so under the advice of the doctor, he targeted the second generation of horizon drugs, that is, nifedipine extended-release tablets or controlled-release tablets.
Extended-release tablets increase the efficacy time of the drug, but generally also need to be taken twice a day, and controlled-release tablets can be released at a uniform rate within 24 hours through unique gastrointestinal membrane control technology and zero-level release pharmacodynamics, ensuring the long-term and stable nature of drug treatment, which is very conducive to the control of blood pressure.
Uncle Zhou chose nifedipine controlled-release tablets. Sure enough, soon, the headache symptoms disappeared and the blood pressure calmed down again. Unexpectedly, 1 year later, Uncle Zhou had symptoms of gingival hyperplasia, and 2 years later, there was ankle edema, but Uncle Zhou did not think about the side effects of the drug, because the drug he chose was already the best antihypertensive drug.
On the other hand, Uncle Zhou is also older, and it is normal for some physical symptoms to appear, but it is not particularly serious, so he does not care too much, even if there are symptoms of rapid heartbeat and facial flushing in the later stage. By chance, after communicating with patients, Uncle Zhou realized that these abnormal symptoms of his own are his own drug problems, and this is a common side effect of horizon drugs.
So Uncle Zhou quickly went to the hospital for examination, and the doctor said that he should have come early! So the doctor changed the valsartan drug for Uncle Zhou, which can avoid the side effects of the horizon drug. After this change of medicine, Uncle Zhou knew that drugs have side effects, we must pay attention to observe their own physical symptoms, abnormalities, and timely communication with the attending doctor to solve.
In fact, in the clinic, the commonly used antihypertensive drugs mainly include calcium channel blockers (CCB), diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor antagonists (ARBs) and β blockers. The type of antihypertensive drugs he has been eating before is the calcium channel blocker class, which belongs to the dihydropyridine class, that is, the level of drugs, and the antihypertensive drugs he is now eating are angiotensin II receptor antagonists, which is usually said to be sartan antihypertensive drugs.
Sartan antihypertensive drugs are especially suitable for patients with left ventricular hypertrophy, heart failure, diabetic nephropathy, coronary heart disease and other diseases, and are contraindicated for patients with bilateral renal artery stenosis, patients with hyperkalemia, and pregnant women, while such drugs may cause severe angioedema, which may also lead to elevated blood potassium, so it is necessary to regularly monitor blood potassium levels.
Uncle Zhou has been taking sartan-type antihypertensive drugs until the last moments of his life, and his efforts to improve his lifestyle and diet cannot be ignored here. It's true that people with high blood pressure can live longer.