Recently, the good news came from the members of the National Natural Science Foundation of China that Professor Wang Xuejing of the Department of Neurology of the First Affiliated Hospital of Zhengzhou University declared the project of "α-Synaptic Nuclein Disease and Cerebral Lymphoid-Meningeal Lymphatic System" funded by the National Natural Science Foundation of China, which is a breakthrough of "zero" in the Talent Project of the National Natural Science Foundation of Zhengzhou University. At the same time, Associate Professor Wang Xuejing is the first clinician in our province to successfully receive funding from the national talent project, which has achieved the first and major breakthrough in the construction of the national "four youth" talent team of the First Affiliated Hospital of Zhengzhou University, and has a positive impact on the improvement of the scientific research competitiveness of the hospital and the construction of the young talent team.
Associate Professor Wang Xuejing won the 2021 National Outstanding Youth Fund Project
Associate Professor Wang Xuejing has worked in the First Affiliated Hospital of Zhengzhou University for more than 10 years, mainly engaged in clinical and basic research on neurodegenerative diseases such as Parkinson's. Parkinson's disease is the most common neurological degeneration disease in the elderly in addition to Alzheimer's disease, the prevalence of people over 65 years old is as high as 10 million/ 100,000, according to relevant parties, by 2030, China's Parkinson's disease patients will exceed 5 million people. Patients often seek medical treatment for movement disorders such as resting tremor, bradykinesia, increased muscle tone, and unstable posture, but have been plagued by non-motor symptoms such as constipation, urinary incontinence, decreased sense of smell, and mental and emotional disorders before the emergence of movement disorders, which not only has a very low quality of life and a very painful life, but also brings great burdens to the family and society. Due to the diverse typing and complex phenotype of Parkinson's disease, the existing diagnostic methods cannot meet the clinical needs, early diagnosis is still tricky, which is an urgent problem to be overcome in nervous system diseases, and there is currently no effective treatment method for delaying the course of the disease at home and abroad.
In view of these medical problems, Associate Professor Wang Xuejing led the research group to make unremitting efforts to use the imaging technology developed by dynamic enhanced magnetic resonance technology to quantitatively evaluate the drainage function of meningeal lymphatic vessels, and found that the drainage of meninges lymphatic vessels in patients with primary Parkinson's disease cleared the dysfunction, and for the first time in the world, a new marker for distinguishing early primary Parkinson's disease and Parkinson's superposition syndrome was proposed, which had high specificity and sensitivity, greatly improved the early diagnosis rate of Parkinson's disease, and was highly praised by peers at home and abroad. At the same time, Associate Professor Wang Xuejing and his research team are also committed to scientific research on new treatment technologies for neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis, which is expected to achieve new breakthroughs in the field of Parkinson's disease treatment in the near future.
Established in 2012, the National Natural Science Foundation of China Outstanding Youth Science Fund, also known as "Xiao Jieqing", is a foreshadowing science and technology support fund of the National Outstanding Youth Fund and enjoys a high reputation. The fund is committed to supporting young scientific and technological talents who are determined to forge ahead in the front line of scientific research, pioneering and innovative, independently selecting research directions to carry out basic research and achieving outstanding results, with a very strict evaluation system and professional research review, and obtaining this funding is a full recognition of the applicant's scientific research projects, scientific research capabilities and scientific research potential, with an important and very important weight, this year only 620 projects in the country have been funded. Associate Professor Wang Xuejing and her scientific research team can stand out from many participating projects across the country, which is the affirmation and reward of her willing to sit on the cold bench, dare to gnaw hard bones, adhere to scientific research and dedication to tackling key problems for many years, and believe that she will achieve greater achievements in future scientific research!
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Wang Xuejing, female, born in 1981, graduated from the Fourth Military Medical University with a bachelor's degree in clinical medicine, and later obtained a master's degree and a doctorate degree in neurology from the First Affiliated Hospital of Sun Yat-sen University and the Xiangya Hospital of Central South University. From 2014 to 2015, he conducted a postdoctoral research in the field of pathogenesis of Parkinson's disease at the NDSU Neuropharmacology Institute in the United States. At present, he is working in the Second Department of Neurology of the First Affiliated Hospital of Zhengzhou University, deputy chief physician, master's and doctoral supervisors, and is also a youth member of the Neurology Branch of the Chinese Medical Association, a member of the Neurodegenerative Diseases Professional Committee of the Chinese Geriatric Health Care Association, a member of the Sleep Disorders Professional Committee of the Chinese Sleep Research Association, a vice chairman of the Youth Committee of the Neurology Branch of the Henan Medical Association, a youth member of the Neurology Branch of the Henan Medical Doctor Association, and the leader of the Neurological Rare Diseases Group of the Henan Neurological Branch. He has been selected as China Outstanding Young Neurologist (2020), Henan Academic technology leader (2019), Henan Outstanding Youth Science Fund (2020), Henan Provincial Health and Youth Discipline Leader (2020), etc. He has presided over 4 national natural science foundations and 5 provincial projects in Henan Province, and published many high-quality research papers in international authoritative journals such as Nat Med, Nat Commun, acta Neuropathol Commun and other international authoritative journals as the first or last corresponding author.
(Henan Science and Technology Newspaper all-media reporter Yu Shichun)