Unless Alexander's army teleports over, logistical supplies alone can drag them to death, as shown in "On Protracted War".
But there are no absolutes in everything, and Alexander is not without the possibility of winning, let's analyze it below.
First, Alexander lived in the fourth century BC, and China was at that time during the Warring States period, when countries fought each other. King Qin's sweeping liuhe proves one thing, fingers clenched together, may not be able to exert the power of fists, but is more likely to be broken one by one. If Alexander can play like Zhang Yi, maybe he really has a winning face.
The State of Qin broke the liuhe
Secondly, the overall armed strength of Alexander's Macedonian phalanx was higher than that of the Warring States at that time. The most eye-catching Wei Wuxian and Qin military merit systems in the middle and late Warring States period did not appear in the Alexander period, and if the two sides were placed in the same time and space to fight each other at this time, it was unlikely that the Warring States would win.
Wei Wuxian
Of course, these are all hypotheses, the Macedonian phalanx due to productivity problems, it was impossible to fight at that time, even if they really conquered the warring countries, they would face high prices and subsequent challenges. For example, Alexander the Great's Macedonian Empire, after conquering Persia and India, eventually led to the fragmentation and decline of the empire due to excessive expansion and political civil strife.
Alexander's last splendor
In a word, win numb.