1. Extraocular muscles
If the extraocular muscles are affected, they are manifested by droopy eyelids on one or both sides, diplopia, and strabismus. It is usually manifested as the patient's eyelids cannot be lifted, the eye fission is small, or one eye is large and one eye is small, the eyeball rotation is inflexible, or even unable to move, and things are seen into double shadows.
2. Facial expression muscles and masticatory muscles
Facial expression muscles and masticatory muscles are affected by: closed eyes are not tight, expressionless, usually the patient's face is a bitter smile, some patients can not drum their cheeks can not blow, chewing weakness when eating, especially when eating dry food is more serious.
3. Limb muscle groups
If the extremities are affected, a common symptom of muscle weakness is: weakness in the arms when the upper extremities are affected; Difficulty combing hair, brushing teeth, dressing; When the lower limbs are affected, the legs up and down the stairs are weak and weak, and they cannot be lifted; When lifting things, the lower limbs feel tired and weak, it is difficult to fall down the steps or on the bus, it is easy to fall when getting off the bus or going downstairs, it is difficult to stand up after squatting, it is difficult to walk, and so on.
4. Bulbar muscle
The manifestations of bulbar muscle involvement are: unclear spitting, tongue outstretched and poor movement, severe patients will also show food in the mouth stirring difficulties, the voice will slowly become smaller with the prolongation of the speaking time, and even lip movement but can not hear the sound, food swallowing is particularly difficult, drinking water is easy to choke cough and so on.