For people who have experienced an acute gout attack, the thought of the pain caused by gout can make you creepy!
This is not alarmist, gout is a common type of arthritis with complex causes. In the case of acute gout attacks, it often appears on the patient's small joints, especially the first bony plantar (big toe), and patients often feel severe pain in the joints, accompanied by symptoms such as redness and swelling, fever and so on.
Even an adult man with a strong body can hardly resist the painful sensations caused by gout. Because of this, ancient Chinese medicine also called gout "White Tiger Calendar Festival".
Going back a few decades, because the living and dietary standards of mainland residents at that time were not developed, the incidence of gout was relatively low at that time. However, in recent years, with the continuous growth of the economic level and the increasingly high level of residents' diet, the incidence of gout has also begun to rise, and the total number of gout patients has reached nearly 80 million.
If you observe diligently, you will find that most gout patients are fat, or even overweight. Thinking about the changes in the diet of mainland residents in recent years, this has to make people think, is there a relationship between gout and obesity?
First of all, we must understand that the essence of gout is actually an increase in the level of uric acid in the body. That is to say, its incidence is based on hyperuricemia.
Under normal circumstances, the body will produce an appropriate amount of uric acid every day, which is the final product of purine metabolism, but the daily production and metabolism of uric acid show a proportional relationship. Once uric acid production and metabolism are out of balance, it will cause a large amount of blood uric acid to accumulate in the body, and then develop hyperuricemia.
The incidence of hyperuricemia is related to genetic factors, and is also affected by gender, age, and unhealthy eating habits. When the blood uric acid level exceeds the standard, a large number of urate crystals will precipitate, because the urate crystals are not heat-tolerant, so they will be deposited on the patient's skin and fat cover weak joints, such as big toes, fingers and so on.
Relevant research and investigation show that obesity is indeed a risk factor for gout, which not only increases the risk of gout, but also the age at which obesity occurs is relatively small, and the disease may occur in youth. The more the BMI index of body weight increases, the more the incidence of gout increases significantly, and there is also a close association between visceral fat and gout.
In other words, hypertriglyceridemia and obesity are both risk factors for the development of gout. This is related to the diet of obese people, because obese people prefer to consume high-fat, high-calorie foods. Red meat, seafood, beer, animal offal, etc., are typical high-purine foods, which can accelerate the synthesis of uric acid after entering the body.
At the same time, serious weight overweight often causes insulin resistance, which inhibits the kidneys' ability to metabolize uric acid through a variety of ways, that is, uric acid is produced in large quantities in the body, but the kidneys are unable to excrete uric acid out of the body. Moreover, obesity also causes an increase in free fatty acids, which increase the synthesis rate of uric acid in the body by affecting the activity of xanthine oxidase.
Under the influence of various factors, the probability of gout in obese people is naturally higher than that of other emaciated people.
Therefore, for obese people, it is necessary to be aware of the harm caused by overweight, learn to control the mouth, open the legs, and control the weight in time. Even people who have already developed gout should start losing weight immediately to reduce the chance of future gout attacks.