With the growth of the infertile population in recent years, assisted reproductive technology has become the choice of more and more families, and 300,000 IVF babies are born every year in the mainland. IVF technology is not only a medical breakthrough, but also a hope for happiness and completeness, helping one infertile family after another to realize the dream of seeking a child.
#什么是试管婴儿
1 generation ivory baby
In vitro fertilization - embryo transfer, commonly known as "first generation IVF", is a technique that takes the eggs and sperm of couples with infertility patients out of vitro, and after the sperm is washed, the eggs are fertilized in vitro and developed into embryos, and the embryos are transferred into the uterine cavity to achieve pregnancy. The fertilization of the egg in this process is close to the fertilization of the egg of natural pregnancy.
2 Second generation IVF
Intracytoplasmic sperm microinjection technology, English abbreviation, ICSI, commonly known as "second-generation IVF", is to inject a single sperm into the oocyte plasma by microinjection, so that sperm and oocytes passively combine for fertilization, form a fertilized egg and carry out embryo transfer to achieve the purpose of pregnancy.
03 Third generation IVF
Preimplantation Genetic Screening, Abbreviation, PGS; Preimplantation genetic diagnosis, English abbreviation, PGD, commonly known as "third generation IVF", refers to the extraction of some cells from ivory fertilized embryos for genetic testing, from which the most in line with eugenic conditions have not been found genetic disease embryos before transfer.
In fact, the common names of "one generation", "second generation" and "third generation" are not very scientific, and it is easy to mislead people that are stronger than one generation, in fact, they are only different indications, and they are technologies developed for different infertility diseases.
Under what circumstances can IVF be done?
1. Infertility caused by female factors cannot conceive naturally after conventional treatment, and can be assisted by in vitro fertilization- embryo transfer (IVF-ET):
1. Egg transport disorders caused by various factors of the woman: such as bilateral tubal obstruction, tubal deficiency, severe pelvic adhesions and other tubal loss of function;
2. Ovulation disorders: refractory ovulation disorders have not been conceived after repeated routine treatment, such as repeated induction of ovulation or combination with intrauterine artificial insemination treatment;
3. Endometriosis: Endometriosis has not yet obtained pregnancy after conventional drug or surgical treatment;
4. Male factor infertility: male infertility with weak and weak spermatozoospermia or compound factors, who have not yet obtained pregnancy after intrauterine insemination treatment, or the severity of male factors is not suitable for intrauterine artificial insemination;
5. Immune infertility and unexplained infertility: repeated intrauterine insemination or other conventional treatment has not yet obtained pregnancy.
Second, if the male factor cannot conceive naturally, pregnancy can be assisted by intracytoplasmic sperm microinjection technology (ICSI):
1. Severe oligospermia;
2. Irreversible obstructive azoospermia;
3. Spermatogenesis dysfunction (excluding genetic defect diseases);
4. Immune infertility;
5. Failure of conventional IVF fertilization or extremely low fertilization rate;
6. Abnormal sperm parietal body.
3. If both parents have a history of genetic diseases and are worried about being passed on to their offspring, they can assist in pregnancy through preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD) techniques:
1. Patients with abnormal number or structure of chromosomes;
2. One of the spouses is a carrier of a sexually linked genetic disease (e.g., hemophilia, pseudo-hypertrophic muscular dystrophy);
3. Single-gene disease patients or carriers who can undergo genetic diagnosis.
What are the advantages of IVF?
First, the high success rate survey shows that women's age is higher than 40 years old, the probability of childbearing is only 20%; above 45 years old, the probability of childbearing is as low as 5%, with the increase of age, it is more and more difficult for women to have children, and they may not be able to give birth to children later.
IVF is a high-tech fertility technology, even if there are forty plus, the egg quality is not good, with the help of IVF, there are also some patients can give birth to healthy babies, greatly improving the chances of pregnancy in elderly women.
Second, avoid repeated operation of test tube technology with the support of frozen embryo technology. The remaining embryos after transfer can be cryopreserved, and in case of treatment failure, the frozen embryos can be thawed and transferred to avoid going through the process of induction and egg retrieval again, and can also save treatment costs.
Third, the scope of application is wide Nowadays, more and more infertility patients choose IVF to assist in pregnancy, because its disease is more widely adapted than other assisted reproductive technologies, and it has a good fertility effect for tubal blockage, tubal resection, endometriosis, infertility caused by unknown causes, etc., which can help infertile families have their own healthier babies.
If you find yourself suffering from infertility, you must treat it in time and do not delay the best gestation time, the best gestation age is a key factor in the success of IVF technology.
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