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The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

For hepatitis B, I think everyone is not unfamiliar.

As a global public health problem, hepatitis B virus has always been a medical focus, and China happens to be the country with the largest burden of hepatitis B virus infection.

According to the existing statistics, there are currently about 70 million HBV infected people in China, and mother-to-child transmission is the main way of virus transmission.

However, recent data show that the prevalence of hepatitis B virus infection in pregnant women in China continues to decline.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

The Lancet sub-journal published a study: the prevalence of HBV among pregnant women in China continues to decline

Recently, the Lancet - Regional Health (Western Pacific) released a data that summarized and analyzed the HBV infection of 90 million pregnant women in 2853 counties in China from 2015 to 2020.

The results of the study show that from 2015 to 2020, the HBV infection of pregnant women in pregnant women in China was moderately prevalent, and the prevalence rate continued to decline, with a decrease of about 25%.

At the provincial and county levels, there are still differences in the prevalence of HBV infection.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

The main reason why the prevalence of hepatitis B virus infection has gradually decreased is that China has standardized and effectively managed HBV-infected pregnant women and their newborns.

Newborn hepatitis B immunoglobulin (HBIG) and hepatitis B vaccination in infants born to HBV-positive pregnant women greatly reduce the likelihood of neonatal infection with hepatitis B virus.

Blocking and blocking mother-to-child transmission of HBV is the key to eliminating hepatitis B.

Therefore, the prevention, diagnosis and treatment of this group can be well regulated, which will play a positive role in the WHO's goal of "eliminating viral hepatitis as a major public health threat by 2030".

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

(Regional differences in HBV carrying rates among pregnant women in china across the population (black line), eastern (red line), central (yellow line), and western (blue line) in China, 2015-2020)

If all five items of hepatitis B are found to be negative, it is necessary to receive hepatitis B vaccine in time

Hepatitis B is a common inflammatory disease, which is mainly due to hepatitis B virus infection.

If this disease is not controlled in time, it is likely to cause cirrhosis of the liver, and even liver cancer, so patients should treat the disease as soon as possible.

Usually, the main examination method for this disease is the five tests of hepatitis B, and the doctor can make a detailed judgment on the patient's condition according to the results of the examination.

When the patient was tested for a hepatitis B pentathlon, it showed that the patient was not only not superficially infected with the hepatitis B virus, but also did not produce antibodies in the body.

Therefore, patients are more susceptible to hepatitis B virus infection.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

In addition, if the patient has been infected with hepatitis B virus before, but has been cured, it is also possible that there will be a hepatitis B pentathlon full negative, which indicates that there is still a small amount of hepatitis B virus left in the patient's body.

Regardless of the type of patient, after the test for hepatitis B pentathlon is fully negative, the hepatitis B vaccine should be injected in time to let the body produce antibodies, so as to avoid the problem of infection.

It is understood that the validity period of the hepatitis B vaccine is about 5-7 years, and the vaccination effect of different patients is also different.

However, it is generally believed that if no antibodies are found after 3 doses of hepatitis B vaccine in accordance with the standard procedure, it is necessary to administer another 3 doses according to the standard procedure.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

In order to give full vaccination on time, the best preventive effect can be better exerted

In order to better avoid the infection of hepatitis B virus and give full play to the "combat effectiveness" of hepatitis B vaccine, it is necessary to vaccinate on time and throughout the process.

For newborn babies, according to the regulations, it is necessary to receive the first injection as early as 24 hours of birth, followed by the second and third doses within 1 month and 6 months respectively.

The same is true for adults, who are also vaccinated on time at the 0, 1, and 6 months of time.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

In general, after vaccination, the body produces a protective hepatitis B surface antibody (HBsAb), and over time, the amount of this antibody will also decrease.

But don't worry too much, the current research data show that usually as long as after vaccination, antibodies will appear, for the protective effect can last for more than 20 years.

Generally after vaccination, you can relax your heart, if you really want to confirm whether there is antibody, you can also check after 1-5 months of vaccination, at this time the antibody titer is the highest.

The Lancet: The prevalence of hepatitis B among pregnant women in China continues to decline? Just because they all do it well

bibliography:

[WANG Guiqiang, DUAN Zhongping, WANG Fusheng,et al. Guidelines for the prevention and treatment of chronic hepatitis B (2019 edition)[J]. Practical Journal of Liver Disease, 2020.

[2] Liver Disease Branch of Chinese Medical Association, Infectious Disease Branch of Chinese Medical Association. Guidelines for the prevention and treatment of chronic hepatitis B (2015 edition)[J]. Chinese Journal of Liver Disease, 2015, Vol. 7, No. 3.

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