Recently, the State Food and Drug Administration approved the "longevity enzyme" NMN as a new raw material for cosmetics. As soon as the news came out, it immediately caused a sensation in the industry, and related concept stocks rose on the same day. What is the "longevity enzyme"? Why is it getting so much attention?
The history of "longevity enzymes" at the beginning
At the beginning of the 21st century, great breakthroughs were made in biotechnology, including cutting-edge technologies such as cloning and gene editing, but these technologies are still in their infancy and are not yet mature. It wasn't until 2013 that Harvard University genetics professor David Sinclair caused a huge stir in an article in Cell that discovered a magical molecule that, after injecting older mice, returned some of its physiological indicators to youthful levels, and this molecule is the "longevity enzyme." Because of this research, Professor Sinclair was also named "the world's 100 most influential people" by Time magazine.
As soon as the news came out, many rich people could not hold back, and Li Ka-shing, the former richest man in China, was one of them, who not only personally took the "longevity enzyme" precursor substance, but also spent 25 million yuan to invest in the "longevity enzyme" market. Sinclair himself also took the "longevity enzyme" himself, and he also mobilized his own family to take it, becoming the first person to "eat crabs". From Sinclair's photographs, we can clearly see the effect of the "longevity enzyme".
Is "longevity enzyme" hype or innovation?
In 2018, Sinclair's team published another paper in which they found that old mice had a significant increase in exercise endurance by 58%-80% after 2 months of oral administration of the "longevity enzyme". Of course, scientists are not only satisfied with the life-prolonging effect of "longevity enzymes" in mice, but more importantly, the role in humans. Just last year, the three countries of China, the United States, Japan three countries on the "longevity enzyme" clinical research has been released, surprisingly, these three large-scale clinical studies have confirmed the safety of "longevity enzyme", and showed its effectiveness of anti-aging in different populations, especially for the improvement of muscle tissue.
Recently, Lin Yi and others of Abinopharm company said in The Lancet that they conducted a random, controlled, double-blind clinical trial and found that "longevity enzyme" is still safe and effective in healthy elderly people aged 40-65. In addition, they also found that "longevity enzymes" can indeed increase the concentration of NAD+ in the blood, and the optimal supplement amount is 600 mg.
The centenarian era is coming?
In our past perceptions, aging is natural and something we can't stop. But the discovery of "longevity enzyme" has made people realize that aging is not "incurable", although we can not do immortality now, but we have some means to delay aging, "longevity enzyme" is one of the more mature means. As the saying goes, eggs can not be put in the same basket, scientists have conducted research in different anti-aging directions, recently, the Israeli research team found that giving healthy elderly continuous hyperbaric oxygen therapy for 3 months effectively delayed the aging of cells, and the physiological age was reduced by 25 years. The results of The Altos, which Bezos invested in, are even more eye-catching, using cell reprogramming to make skin cells 30 years younger in just 13 days.
Hyperbaric oxygen and cellular reprogramming techniques show us their enormous potential to fight aging.
In today's highly developed medicine, our understanding of aging is becoming more and more profound, and we have more and more anti-aging means, I believe that in a few decades, human beings can enter the era of 100 years old.
—— TIMEPIE ——