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Cover news reporter Ning Zhi video Liang Jiaqi intern Xu Yingman
How terrible is radiation damage? It has been reported that after someone picks up the radioactive source, the skin will gradually necrosis, amputation, and even death, and he will suffer mental and physical pain for a long time, and his relatives who are in close contact with him will also suffer from nuclear radiation damage.
Last year, Mr. Luo also experienced terrible radiation damage due to machine failure, but fortunately, he found the Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, and after 3 months of treatment, he saved his hands.
After being discharged from the hospital, Mr. Luo presented a pennant to the medical workers
Cases//
"If the treatment is not timely, only amputation"
Recently, Mr. Luo was successfully discharged from the Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, and when he was discharged, he showed a long-lost smile: "Now I feel very satisfied, no pain and no itch, thank you very much to the doctors here!" ”
Mr. Luo recalled that at about 12:00 noon on November 28, 2020, he encountered a ray leak while performing instrument maintenance, "there were no symptoms at the time of the injury, and after two days, the hands began to blister, scab, and the skin gradually festered." I couldn't sleep every night and needed painkillers to fall asleep. ”
In December last year, he searched for medical treatment everywhere, and finally was introduced to Professor Yu Daojiang, director of the Burn Plastic Surgery Department of the Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, and deputy leader of the Sichuan Provincial Nuclear and Radiation Medicine Rescue Team, and later successfully saved his hands under the joint cooperation of multidisciplinary teams such as burn plastic surgery, nuclear medicine and urology.
The Second Affiliated Hospital of Chengdu Medical College and the Multidisciplinary Joint Clinic of the 416th Hospital of Nuclear Industry
Director Yu Daojiang told reporters: "When the patient first came, his hands and face were damaged by radiation, and the soft tissues such as the skin tendons of the fingers of the hands gradually necroticized and the pain was severe, and he needed to take pain injections to fall asleep. If he could not be rescued in time, he could only amputate his leg. ”
Treatment//
Using several new technologies, the treatment time has been reduced by one-third
"We first have to solve the problem of pain so that he can have a good night's sleep, and the second is to solve the problem of self-care in his life and rescue his hands." Yu Daojiang said, so the core of the team treatment plan is "fast".
How to be "fast"? Yu Daojiang's team used a number of new technologies, including fluctuating negative pressure immersion baths with hydrogen-rich water, freestyle multi-finger skin soft tissue preconditionation based on ultra-thin flap-based multi-finger skin, angiogenesis regulation based on reversible clipping of perforating vessels, and multiple SVF (adipose tissue matrix components) and fat injection grafts.
How is it treated? Yu Daojiang gave an example, "For example, we extract fat from a patient's stomach and extract the extravascular matrix inside the fat, which can be used to treat radiation damage." ”
"Our team has more than ten years of experience in the field of radiation damage, including Professor Cao Jianping of the School of Radiation Medicine and Protection of soochow University School of Medicine, Professor Zhang Shuyu of Nuclear Industry 416 Hospital, sichuan university, etc. Based on some basic theories and experiences, we made innovations in clinical treatment, and finally completed the treatment for patients in a relatively short period of time. Yu Daojiang introduced that compared with the traditional treatment time, the course of the disease has been shortened by about one-third.
Jiang Zhiqiang, Secretary of the Party Committee of the Second Affiliated Hospital of Chengdu Medical College and The 416th Hospital of nuclear industry (first from the left), visits the patients
Extension//
Basic research provides a theoretical basis for clinical treatment
With the support of the National Natural Science Foundation of China Outstanding Youth Science Foundation Project, the Joint Fund Key Project, the Surface Project and the China National Nuclear Corporation Young Talents Project, the research team has conducted more than 10 years of basic research on the mechanism and treatment strategy of radioactive skin injury, published more than 30 papers in Chinese and English, and obtained 12 Chinese and American patents. The paper "Research on New Technologies for the Treatment of Radioactive Skin Damage in Nuclear and Radiation Emergencies" led by Professor Zhang Shuyu was published in this year's Journal of Scientific and Technological Achievement Management and Research.
Zhang Shuyu introduced: "Our basic research team mainly focuses on what changes occur after skin cells or skin tissue are exposed to nuclear radiation. Why is it different from ordinary burn trauma, and why is it so badly diseased? ”
To this end, the team did a lot of research. "For example, we have a study that, based on experiments, we can reduce the radiation damage of patients through dietary interventions. Such a plan was used in Mr. Luo's clinical treatment this time. ”
It is understood that Professor Cao Jianping and Professor Zhang Shuyu's research group "hopes to reveal a pathogenesis of radiation skin injury through a series of studies, and at the same time find a new marker for radioactive skin injury to carry out effective dose estimation, providing a theoretical basis for clinical treatment." ”
The new technology of radiation skin injury treatment developed by Professor Yu Daojiang, Professor Zhang Shuyu and other teams can not only be used for the treatment of patients with radiation injury, but also for the treatment of tumors, radiotherapy patients and common diabetic foot, pressure sores and other patients, which will improve the quality of life of patients with these refractory wounds.
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