Collagen is the main structural protein in the extracellular matrix of various connective tissues in the body. It is the main component of connective tissue and is the most abundant protein in mammals, accounting for 25% - 35% of the total protein content of the body. Collagen is made up of amino acids that are held together to form an elongated fiber called a triple helix. It is mainly found in connective tissues such as cartilage, bones, tendons, ligaments, and skin. Common collagen proteins are mainly bovine collagen (mainly from dairy cows), porcine collagen (extracted from the skin, bones and connective tissue of pigs), and marine biocollagen (made from fish-derived collagen peptides).
Collagen has many medical uses in the treatment of bone and skin complications, and is widely used in dermatology, burns, laser cosmetology and other subjects due to its powerful skin repair function, so it is also known as medical-grade bioactive collagen, referred to as medical active collagen, and occasionally called medical collagen. Medical collagen can be used in vascular grafting, cartilage repair, wound care, bone grafting and diagnosis, and can also be used as hemostatic materials and tissue scaffold materials. Studies have shown that the use of collagen for bone grafting is the most common, with the highest market share of 24.52% in 2020. Since bones make up the structure of the body, it is crucial to maintain its strength even when injured. Collagen is used in bone grafting, mainly because it has a triple helix structure that makes it a very strong molecule. The effect it acts on the bones is ideal because it does not compromise the structural integrity of the bones. The triple helix structure of collagen prevents it from being broken down by enzymes, which makes cells adhesion, which is important for the proper assembly of the extracellular matrix.
Analysis of the current situation and prospect forecast of the medical collagen market
According to research data, the total market value of medical collagen in Europe and the United States was US$361 million in 2015, which increased to US$475 million in 2020, with a compound annual growth rate of 22.77% from 2015 to 2020. On this basis, we carried out a series of functional calculations and deduced the data of the past 5 years with scientific models. Finally, we predict that the European and US medical collagen market will be worth $627 million by 2025.
The geographical market concentration of medical collagen is very high. The United States is the largest revenue market, and from 2015 to 2020, it has been ranked first in the medical collagen revenue market. In 2015, its market value was $190 million, and by 2020, its market value increased to $246 million, accounting for a market share of 51.88%, with a compound annual growth rate of 11.23% between 2015 and 2020. The United States is the world's largest developed economy, with political and social stability, a sound legal system, a sound market system, and rapid development. It is a leader in North American market capacity, technological prowess, educational innovation, and labor productivity. From the perspective of production, the United States has developed various industries, with many local brands and good market competition. In addition, European countries such as Germany, France, Italy, the United Kingdom and Spain also occupy a certain market share. In 2020, Germany ranked first in the European market with a market share of 11.37%, and has become the fastest growing market in Europe, with a good development trend.
In 2020, Integra Life Science ranked first in the European and American medical collagen market with a market share of 38.97%, SDM Biomedical ranked second with 17.96%, and Collagen Matrix ranked third with a market share of 9.48%. The top six companies in Europe and the United States accounted for 79.32% of the entire market.
The impact of the pandemic on the medical collagen market
The impact of the pandemic on the medical collagen market will involve all major links and all entities in the industrial chain. In order to avoid large-scale population movements and gatherings, countries have adopted prevention and control measures such as home quarantine and the extension of the Chinese New Year holiday. More and more cities are entering a state of first-level response, strictly controlling the movement of people to prevent the spread of the epidemic. This made it impossible for non-local employees to return or arrive immediately, the number of employees was insufficient, and normal commuting was severely affected, resulting in large-scale shutdowns. Road closures and village closures in various regions have hampered the transport of raw materials such as pork, pepsin and acetic acid, as well as salt products. The existing reserves of raw and auxiliary materials may not be able to meet the needs of normal production, and most companies cannot maintain production with raw material inventories. The operating costs of medical collagen companies will be affected by the increase in raw material and logistics costs, the development of online shopping Xi habits of consumers and distributors, and the difficulty of recycling after the epidemic eases. In addition, consumer demand for products will also decrease due to declining revenues, which further poses challenges to business development.
In addition, the increasing pandemic has posed severe challenges to the global healthcare system. In related reports, the Center for Surgical Efficacy and Patient Safety at Massachusetts General Hospital said that the number of surgeries canceled due to the pandemic worldwide will reach about 28.4 million by 2020. Most of the canceled surgeries are for non-cancer patients. The mass cancellation of surgeries during the pandemic means that the demand for medical collagen in medical institutions will also be significantly reduced in the short term.
However, when the pandemic eases, medical facilities will continue to digest canceled and postponed surgeries for the next one to two years. The accumulation of surgical procedures will lead to a significant increase in the demand for medical collagen in healthcare facilities. Therefore, although the epidemic will have a certain impact on the company's performance in the short term, in the long run, the medical collagen industry is expected to have great potential. In addition, in the post-pop era, people will pay more attention to a healthy lifestyle and concept of life. At the same time, people are starting to focus on healthier products, hoping that they will have health benefits. Collagen is an important source of nutrients and is rich in amino acids, especially amino acids that cannot be synthesized by the human body. Regular supplementation of appropriate amounts of collagen can help enhance the function of various tissues and organs and enhance the body's immunity. Therefore, collagen, as a basic nutritional protein, will benefit people's health. People's consumption concept has been further improved, and the medical collagen market has a broader prospect.