According to Jiangsu public news channel "News 360", HPV vaccination is an effective way to prevent cervical cancer. Recently, the official website of the World Health Organization released the news that only 1 dose of HPV vaccine can produce the same immune effect as 2 doses and 3 doses. So, is the HPV vaccine enough for a single shot?
[The protective effect of one injection has yet to be confirmed, and experts recommend that they be vaccinated according to the three-dose plan]
From 4 April to 7 April, the World Health Organization held a meeting of the Strategic Advisory Group on Immunization to review studies on the efficacy of single dose HPV vaccination over the past few years, and concluded that a single dose of HPV vaccination can be effective in preventing cervical cancer caused by persistent HPV infection, comparable to the effectiveness of two or three doses.
The New England Journal of Medicine also recently published an article titled "Efficacy of Single Dose HPV Vaccine in Young African Women", which concluded that 1 dose of HPV vaccine and multiple doses are similar to the effectiveness of persistent infection. However, the study only looked at the data for 18 months after vaccination, and there was no long-term data to support it. On April 16, a media spokesperson for the headquarters of HPV vaccine production company Merck responded that there is still a huge data gap in the single dose program. Experts suggest that women should still be vaccinated according to the three-dose regimen.
Zhang Hongxiu, chief physician of the Women's Health Department of Jiangsu Provincial Maternal and Child Health Hospital, said that the single-dose plan is a recommendation discussed by the expert group, and whether it can be adopted is not yet clear. Before there is a very clear and very effective big data research verification, it should still follow the recommendations of the manual, which is a "0, 1, 6" scheme with three injections.
【Community hospital: HPV vaccine supply is tight, need to make a regular number rush appointment】
According to expert analysis, the reason why the World Health Organization's Strategic Expert Group on Immunization proposed a new vaccination recommendation is more based on the concerns about the slow introduction of HPV vaccine into the immunization program, the low overall population coverage rate, and the shortage of HPV vaccine, and the cost of a single dose of HPV vaccine is lower, which can improve the vaccination rate and accelerate the goal of eliminating cervical cancer. The reporter learned from some community hospitals in Nanjing that due to various factors, the current supply of HPV vaccine is relatively tight.
Du Yan, deputy director of the Public Health Department of Nanjing Xinjiekou Community Health Service Center, said that in March, an appointment for a nine-valent vaccine has been launched, and about 30 nine-valent cervical cancer vaccines have been supplied. Make a regular number snatching appointment through the early public account notification, and try to give priority to residents in the jurisdiction to receive the first dose of cervical cancer vaccine. At present, the situation of bivalent and quadrivalent vaccines is also relatively tight, and in the tense situation, try to ensure the supply of the second and third doses. Look at the supply of vaccines in the later stage, and then make relevant online first injection appointment activities.
【Free vaccination for girls in the first year of junior high school in Nanjing is expected to complete the first dose in the first half of this year】
In order to widely cover and promote the HPV vaccine, many places in China have launched free or subsidized HPV vaccine vaccination. At the end of 2021, Wuxi and Lianyungang, Jiangsu Province, launched the work of free HPV vaccination for women of appropriate age. The reporter learned from the Nanjing Municipal Health Commission that the first female student in the junior high school in Nanjing is expected to complete the first free HPV vaccine in the first half of this year.
Zhang Hongxiu said that about 99% of cervical cancer is caused by persistent HPV infection, and in the range that meets the age range of vaccination, the earlier the HPV vaccine is better.
At present, the vaccination age of domestic bivalent and imported bivalent HPV vaccines is 9 to 45 years old. The age of vaccination for imported quadrivalent HPV vaccines is 20 to 45 years. The age of vaccination for imported nine-valent HPV vaccines is 16 to 26 years old.
Jiangsu TV reporter / Wang Leping Yan Bin Editor / Hu Chao