On 23 February, the Singapore Health Sciences Board reported that as of 31 January, there had been 280 reports of adverse childhood vaccine reactions in Singapore, of which 10 were serious adverse reactions.
From 27 December to 31 January 2021, Singapore received a total of 238,253 doses of childhood vaccine with an adverse reaction rate of 0.12% and a serious adverse reaction rate of 0.004%.
These two proportions are close to those in the adolescent and adult groups.
Unlike the adolescent and adult groups, there were no cases of myocarditis or pericarditis in the 5- to 11-year-old group.
Adverse reactions in the children's group included 3 cases of eyelid, face and lip swelling, urticaria, dizziness, fever, rash, chest tightness, and shortness of breath.
Serious adverse reactions include epilepsy, appendicitis, decreased blood pressure, allergic reactions, and swollen capillaries.
According to the Health Sciences Board, these adverse reactions and serious adverse reactions are not necessarily directly related to vaccination, some are latent diseases, and some happen to have symptoms after vaccination.
Children aged 5 to 11 years in Singapore are vaccinated with the Pfizer/Fupiter vaccine.
Pfizer vaccines have the highest rate of adverse reactions
As of January 31, Singapore had received a total of 13,213,692 doses of COVID-19 vaccine, of which Pfizer/Fubitech accounted for 74.48%, Modena accounted for 22.05%, Kexing accounted for 2.79%, and Sinopharm accounted for 0.68%.
The Health Sciences Bureau noted that since different vaccines are initiated at different times, and because inactivated vaccines account for only a very small proportion of the population (3.6%), it is not appropriate to directly compare adverse reaction reports from different vaccines.
The Health Sciences Bureau emphasizes that, based on the data currently available, the benefits of the Kexing, Pfizer/Fubister and Modena vaccines provided by vaccination authorities under the national vaccination program outweigh the risks.
The mRNA categories of Pfizer/Fubixil and Modena were vaccinated with a total of 12,755,259 doses, with 15,655 adverse reactions, accounting for 0.12%, and 820 serious adverse reactions, accounting for 0.006%.
Pfizer was vaccinated with 9.84 million doses
Adverse reaction rate 0.13%
Serious adverse reaction rate 0.007%
Pfizer/Fubitech received a total of 9,841,084 doses, with 12,770 adverse reactions, accounting for 0.13%, and 664 serious adverse reactions, or 0.007%.
Among the four current vaccines, Pfizer has the highest proportion of adverse reactions.
Modena received 2.91 million doses of the vaccine
Adverse reaction rate 0.10%
Serious adverse reaction rate 0.005%
Modena received a total of 2,914,175 doses, with 2,885 adverse reactions, accounting for 0.10%, and 156 serious adverse reactions, accounting for 0.005%.
The adverse reaction symptoms in the mRNA vaccine group were similar to those of the cold vaccine, including urticaria, dizziness, shortness of breath, chest tightness, night sweats, fever, headache, muscle soreness, swelling and pain at the injection site, etc., and generally disappeared within a few days.
Serious adverse reactions in the mRNA vaccine group included 88 systemic allergic reactions and 55 severe allergic reactions, including chest pain, abnormal blood pressure, myocarditis, pericarditis, arrhythmia, rapid heartbeat, cerebral venous sinus thrombosis, migraine, facial paralysis, severe dermatitis, kidney inflammation, tinnitus, asthma, menstrual disorders, appendicitis, etc.
Coshing has been vaccinated with nearly 370,000 doses
Adverse reaction rate 0.08%
Serious adverse reaction rate 0.006%
Kexing received a total of 369,083 doses, with 299 adverse reactions, accounting for 0.08%, and 22 serious adverse reactions, with a proportion of 0.006%.
Adverse reactions in the Koching group included urticaria, angioedema, dizziness, shortness of breath, chest tightness, and generally disappeared within a few days.
There were 22 serious adverse reactions in the Kohin group, including 12 systemic allergic reactions, all of which were from people who had previously received the mRNA vaccine and had allergic reactions or those who had a history of drug allergies; the other 10 serious allergic reactions, including myocarditis, facial paralysis, thrombosis, paralysis, hypertension, rapid heartbeat, tinnitus, etc.
Sinopharm was vaccinated with nearly 90,000 doses
Adverse reaction rate 0.05%
Sinopharm administered a total of 89,350 doses, with 41 adverse reactions, accounting for 0.05%, and 6 serious adverse reactions, accounting for 0.007%.
Adverse reactions in the Sinopharm group include urticaria, angioedema, paralysis, syncope, chest tightness, and generally disappear within a few days.
There were 6 serious adverse reactions in the Chinese Sinopharm group, including low platelets, chest pain and visual impact, rheumatoid arthritis, and recurrence of hypothyroidism.
Intensive needle vaccination
There were 15 cases of myocarditis and pericarditis
As of 31 January 2022, a total of 3,194,494 people had received the Pfizer/Fupiter and Modena vaccines as boosters. 69% of those vaccinated against Pfizer/Fupitech and 31% against Modena.
Vaccinated with Pfizer/Fupiter as a booster, there were 553 adverse reactions, a proportion of 0.03%.
Vaccinated with Modena as a booster, there were 289 adverse reactions, the same proportion of 0.03%.
Among the more than 3.19 million doses of strengthening injections, 73 serious adverse reactions, a proportion of 0.002%, including 15 cases of myocarditis and pericarditis.
Some of the adverse reactions that authorities are closely watching
According to the Health Science Bureau, the following types of adverse reactions are currently being closely followed:
I. 88 anaphylaxis
At present, the chance of anaphylaxis is 0.89 per 100,000 doses, and the mRNA vaccine has so far seen 88 systemic anaphylaxis reactions, which occur after the first dose than in the second dose. As for the booster needle, there have been no reports of anaphylaxis. All patients who developed this adverse reaction recovered after administration.
Second, 116 cases of myocarditis, pericarditis, Kexing appeared 1 case
At present, the incidence of myocarditis and pericarditis in the local area is 5 to 7 per 100,000 people per year, for a total of 280 to 400 cases per year.
Since the initiation of mRNA vaccination against coronary disease, myocarditis and pericarditis have occurred after the first dose, with 1.08 cases per 100,000 doses. At present, Singapore has received more than 12.7 million doses of mRNA vaccine, and 115 cases of pericarditis and myocarditis have been reported. In addition, 1 case of myocarditis was reported in those who were vaccinated against Koching.
3. 13 suspected cerebral venous sinus thrombosis
To date, the Department of Health Sciences has received 13 reports of suspected cerebral venous sinus thrombosis, all from the mRNA vaccine group.
Authorities noted that infection with the coronavirus disease can also lead to cerebral venous sinus thrombosis. The benefits of vaccination outweigh the risks.
Source: Singapore Eye
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