Can Helicobacter pylori infection be cured?

In recent years, with the improvement of people's living standards and the improvement of health awareness, Helicobacter Pylori (Hp) has gradually entered the public's field of vision and has been understood by more people. Hp is one of the main causes of chronic gastritis and gastroduodenal ulcers, and is also a class I carcinogen of gastric cancer published by the World Health Organization.

Author: Secret Venting

01

What symptoms can I have with Hp infection?

For example, recurrent bloating, belching, epigastric pain, worsening of breath, etc., may be the manifestation of hp infection.

02

Relationship between Hp infection and chronic gastritis, peptic ulcer, stomach cancer

At present, a number of studies have shown that Hp infection significantly increases the risk of gastritis, precancerous lesions or stomach cancer, and accelerates the progression of gastric disease.

It can also lead to lingering or recurrent episodes of peptic ulcer lesions. Eradication of Hp eliminates persistent inflammation in the stomach, prevents further damage to the gastric mucosa, and improves the microenvironment and acid-secreting conditions in the stomach. For people with atrophic gastritis, hp eradication can delay the progression of atrophy and intestinal metaplasia while improving abdominal discomfort symptoms.

03

What should I do if I am infected with Hp?

Hp can be transmitted through saliva and has a higher rate of Hp infection due to continental dietary habits. In 2017, the National Consensus on the Management of Helicobacter pylori infection mentioned that once Hp infection is identified, Hp eradication therapy should be initiated regardless of whether the patient has symptoms or whether other problems are found on endoscopy.

If the patient is found to be infected with Hp through examination, there is no need to be too anxious, there is a mature drug regimen for eradicating Hp, go to a professional medical institution, and carry out standardized anti-Hp treatment. At the same time, in daily life, we develop good habits such as using dishes and chopsticks alone and using public chopsticks when eating out.

04

What should I pay attention to during taking the drug?

At present, the commonly used eradication regimen is a quadruple therapy of two antibiotics + PPI + bismuth, the duration of medication varies from 7 to 14 days, and the regimen will also be adjusted according to the patient's degree of infection, whether there is antibiotic allergy, and the type of Hp strain. It should be noted that during the medication, it is necessary to avoid eating spicy and irritating foods and avoid drinking alcohol; in addition, due to the large amount of antibiotics used, the amount of water used during taking the drug can be increased as appropriate. Some patients will have diarrhea, abdominal pain, dizziness and other drug side reactions, due to the influence of bismuth agents may also appear stool color darkening, such as severe symptoms need to seek medical attention in time.

05

What are the possible causes of failure to eradicate Hp?

(1) 13C urea breath test (13C-UBT) is the most commonly used method to detect Hp. However, the results of this examination may be affected by the following factors: recent use of proton pump inhibitors, such as xxprazole drugs Recent use of antibiotics, traditional Chinese medicines, etc. Oral hygiene interference Eating and drinking within 2 hours before the examination. In similar situations, the accuracy of 13C results may be affected.

(2) According to clinical statistics, about 20% of the infected strains of patients may have different degrees of antibiotic resistance, the most common such as clarithromycin and metronidazole resistance. In such patients, it may be recommended to stop treatment for more than 3 months, and the antibiotic regimen may be adjusted as appropriate according to the susceptibility.

This article is produced by Jingdong Health Internet Hospital

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