Diabetic nephropathy, one of the common complications of diabetes, has no obvious symptoms in the early stages. The main diagnostic index of Western medicine is proteinuria, which is not abnormal in the early stage, and when the indicators are obvious, the kidney function has often been seriously failed, which brings great pain to patients and their families. The clinical manifestations of diabetic nephropathy are proteinuria, edema, increased blood pressure, anemia, etc., and even glomerular damage and renal insufficiency in the later stage. Clinically used proprietary Chinese medicines include Haikun Kidney Xi Capsules, Bailing Capsules, Huangkui Capsules and so on.
Haikun kidney hi capsules
Haikun Kidney Xi Capsule is a natural marine medicine extracted from kelp, which has the effect of "reducing turbidity through the intestines, strengthening the spleen and dampness". The main component is fucoidan sulfate, which is a water-soluble heterosaccharide, which is a substance with efficient adsorption effect, which can fully absorb small molecule toxic substances (such as uric acid, indole, amines and other protein metabolites), medium molecular toxic substances (such as parathyroid hormones, polypeptides, etc.) and macromolecular toxic substances (such as glucagon, lysozyme, etc.), and directly excrete them from the body.
Studies have shown that fucoidan sulfate can also improve renal blood flow, delay glomerulosclerosis, promote the repair of impaired kidney cell function, remove reactive oxygen radicals, inhibit lipid peroxidation reactions in the body, and regulate immune mechanisms. In clinical treatment, Haikun Renxi capsules can significantly improve the symptoms of traditional Chinese medicine in both patients with stage III diabetic nephropathy and stage IV diabetic nephropathy, and the urine protein, creatinine level, C-reactive protein, triglycerides are significantly reduced, and the glomerular filtration rate is significantly increased.
Bailing capsules
Bailing capsule is a proprietary Chinese medicine with wide clinical application in nephrology, which has the effect of reducing urine protein, alleviating cytolysosomes and alleviating cell lipid peroxidation damage, protecting tubular cell sodium-potassium-ATPase, promoting tubular cell proliferation and cell repair, and inhibiting glomerular compensatory hypertrophy. Studies have confirmed that Bailing capsules have a significant protective effect on the kidneys, lungs, liver, etc. At the same time, studies in recent years have shown that Bailing capsules also have central sedation, enhance immune function, anti-inflammatory, anti-hypoxia, regulate endocrine, anti-tumor and other effects.
In the clinic, patients with early diabetic nephropathy were randomly divided into control group and observation group, and the control group adopted conventional treatment, and the observation group added bailing capsules on the basis of the control group, both of which were treated for 12 weeks; the two groups were observed for blood glucose, blood pressure, blood lipids, urea nitrogen, blood creatinine, urinary protein excretion rate, C-reactive protein and other indicators. The results showed that Bailing capsules had a good effect on the treatment of early diabetic nephropathy, and had the effect of reducing proteinuria and improving renal function.
However, the vast majority of Bailing capsules for the treatment of chronic kidney disease are combined with other drugs. Among them, Bailing capsules and benazepril, sodium ferulate, irbesartan, valsartan, captopril, prostaglandin E1, glutathione, calendulacin, calcinaticin, pancreatin and other literature reports on the treatment of early diabetic nephropathy. Tip, Bailing capsules combined with Western medicines with renal protective effects can obtain a multiplier effect with half the effort.
Yellow sunflower capsules
Yellow sunflower capsules, is the extract preparation of chinese medicine yellow marshmallow flower, the main active ingredients include flavonoids, polysaccharides, tannic acids and long-chain hydrocarbons, etc., its sexual taste is sweet and cold, has the effect of clearing damp heat, detoxification and swelling, suitable for diabetic nephropathy damp fever such as edema, proteinuria, hematuria, tongue yellow greasy treatment. Experimental studies and clinical practice have confirmed that yellow sunflower capsules can reduce proteinuria, protect kidney function, and delay the progression of diabetic nephropathy.
In clinical practice, yellow sunflower capsules combined with valsartan can effectively reduce the excretion of urine protein in patients and protect kidney function, and the effect is better than that of valsartan alone. In diabetic nephropathy, hyperglycemia and lipid metabolism disorders not only aggravate the damage to kidney tissue, but also stimulate the production of inflammatory factors, which in turn cause glomerulosclerosis and interstitial fibrosis. Studies have shown that yellow sunflower capsules can reduce the inflammatory response in patients with clinical-stage diabetic nephropathy.
Tubular damage also plays an important role in the occurrence and development of diabetic nephropathy. In the early stages of diabetic nephropathy, tubular damage occurs simultaneously with glomerular lesions, even before glomerular lesions. In patients with clinical diabetic nephropathy, the tubular function is more seriously impaired, and the yellow sunflower capsule has the effect of protecting the tubular epithelial cells of the kidney, which is also related to reducing the inflammatory response of patients.
In short, Haikun Kidney Xi Capsules, Bailing Capsules, and Yellow Sunflower Capsules are derived from the active ingredients extracted from kelp, fermented Cordyceps sinensis powder, and Yellow Marshmallow Flower, which are natural, safe, effective, and non-toxic. Their protective mechanisms for diabetic nephropathy are different, and they can intervene in all aspects of the occurrence and development of diabetic nephropathy, improve clinical symptoms, reduce proteinuria, and protect kidney function.