Under the incentive of the three-child opening policy, the demand for assisted reproductive technology in China is getting higher and higher, and the phenomenon of the number one is even difficult to find in major domestic fertility centers. In the various technologies of assisted reproduction, the most mainstream is the "in vitro fertilization" method, which is what we often call "IVF", and IVF technology is divided into three generations, today AA69 Fertility Center will come to talk to you, what is the difference between the third generation of IVF and the second generation of IVF?
The second generation of IVF technology, that is, intracytoplasmic sperm injection (ICSI), after receiving male semen, the doctor will first optimize the semen, and then select a relatively strong sperm, use a very fine needle to inject the sperm directly into the egg, fertilize the egg, and then implant the formed embryo into the uterine cavity, so as to achieve the purpose of pregnancy.
This approach can solve the problem of low sperm count and weak motility that leads to the inability to combine with the egg. It is suitable for people with oligospermia, weak, teratogenic spermatozoa, irreversible obstructive azoospermia, spermatogenesis dysfunction (caused by genetic defect diseases), and in vitro fertilization failure due to abnormal egg zona pellucida or other reasons.
The third generation of IVF technology, preimplantation genetic diagnosis/screening (PGD/PGS), is that after the retrieved sperm and eggs are combined to form an embryo, the doctor will test all the formed embryos and select the embryos with the most normal chromosomes or genes for transfer.
This approach can help some couples who carry abnormal chromosomes or genes to have long-term infertility or repeated miscarriages, and even give birth to babies with major genetic diseases. Suitable for single gene-related genetic diseases, chromosomal diseases, poor maternal history, elderly women, and high-risk populations who may have abnormal offspring.
It can be seen that the third generation of IVF technology and the second generation of IVF technology are applicable to different groups of people, and the third generation of IVF technology organically combines reproductive medicine and genetics, which is to carry out genetic analysis before the embryo does not implant, advance the prevention of genetic diseases to the pre-pregnancy stage, and control birth defects at the source.