Aspirin as an antipyretic analgesic, because it has a very wide range of effects: it can prevent cardiovascular and cerebrovascular diseases, but also as a secondary prevention drug for cardiovascular and cerebrovascular diseases, and at the same time can relieve fever and analgesia, and can prevent thrombosis after surgery. Therefore, it can often be seen clinically. For many people with cardiovascular and cerebrovascular diseases, it is necessary to take aspirin all year round.
But in practice, I met many people on when is the best time to eat aspirin? Can it be taken for a long time? Who can't take it? These problems are very confusing, today Dr. Zhou will take you to learn more about it.
In the early stage, aspirin was mainly used as a nonsteroidal anti-inflammatory drug, that is, antipyretic analgesics, mainly used to treat headaches and fevers caused by colds, and for headaches, toothaches, joint pain, neuralgia, muscle pain and dysmenorrhea can have a better relief effect. However, with the deepening of research on aspirin, it has been found that the main component of aspirin, acetylsalicylic acid, can acetylate the epoxygenase of platelets, thereby reducing the synthesis of serum acid A2, and this process plays an irreversible inhibitory effect on reducing platelet aggregation, so it can effectively resist platelet aggregation. This can play a huge adjuvant therapeutic role in the clinical prevention and treatment of platelet aggregation diseases, such as coronary heart disease and postoperative treatment, so it has been widely used in the prevention and treatment of cardiovascular and cerebrovascular diseases. In real life, many patients take aspirin for a long time to use this pharmacological feature to prevent and treat transient ischemic attacks, coronary heart disease, myocardial infarction, cerebral infarction and so on.
With the development of interventional medicine, aspirin has come into play again. Because the postoperative complication of interventional therapy is that it is easy to have thromboembolism, and the anti-platelet aggregation of aspirin can play a good role, so it is also routine to use aspirin to prevent thrombosis after surgery and interventional surgery after surgical procedures such as pelvic surgery and pelvic surgery.
<h1 class= "pgc-h-arrow-right" > so can aspirin be used for a long time? </h1>
Whether aspirin can be taken for a long time depends mainly on the user's own condition. Aspirin is not recommended for patients with a history of gastrointestinal bleeding, gastric ulcers, and gastritis, because aspirin is a nonsteroidal anti-inflammatory drug, which can aggravate gastric ulcers, promote the destruction of the gastrointestinal mucosa, and cause gastrointestinal bleeding. The specific mechanism is because acetylsalicylic acid is a weakly acidic fat-soluble drug, which can destroy the physiological carbonate barrier on the surface of the gastric mucosa, and acetylsalicylic acid can inhibit the synthesis of prostaglandins, which is the protective agent of the gastric mucosa, so it is easy to aggravate the damage to the gastric mucosa and aggravate gastric ulcers, so patients with the above medical history are not recommended to use aspirin.
However, lifelong aspirin is recommended for patients without any history of gastrointestinal-related diseases, and for users with a history of heart disease or cerebral infarction. However, in the process of taking, it is also necessary to observe the relevant symptoms in detail, such as black stool, abdominal pain, gout and other discomforts, if there are serious complications, it is also necessary to stop or change the dressing.
<h1 class= "pgc-h-arrow-right" > so when is the best time to take aspirin? </h1>
Clinically, the general dose of aspirin is once a day, and the high incidence of cardiovascular and cerebrovascular system diseases is generally in the early morning, plus the peak period of aspirin is to take 3-4 hours of action, then if taken in the morning, can not let the peak of the drug effect play the best role, and take it before falling asleep, you can well achieve the effect of inhibiting platelet aggregation, play a good role in preventing cardiovascular disease.
In order to better use aspirin, there is also a key point is the need to strictly clarify the contraindications, from the current study found that aspirin mainly has the following nine contraindications:
1. It is forbidden for those who are severely allergic to this product (acetylsalicylic acid);
2. It is not recommended for women under the age of 55, men less than 45 years old or more than 85 years old;
3. Patients with hemophilia or thrombocytopenia are contraindicated in use;
4. Patients with a history of gastrointestinal bleeding, or patients with severe gastrointestinal ulcers, contraindicated;
5. Contraindicated in the treatment of perioperative pain in coronary artery bypass surgery (CABG).
6. Taking other hormones, nonsteroidal anti-inflammatory, antiplatelet drugs, should be strictly evaluated by the doctor before deciding whether to use;
7. Patients with severe liver, kidney and heart failure should be contraindicated in use;
8. Infants under 3 months of age are contraindicated, and pregnant women within 3 months of pregnancy are contraindicated;
9. When diabetic patients take insulin, the use of aspirin requires strict monitoring of blood sugar, and aspirin cannot be used with methotrexate.
This article is for learning and communication purposes only and is not intended as a basis for clinical diagnosis and treatment.
Thanks for reading!
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