Disease and human beings come together, and the unremitting pursuit of health makes medical treatment continue to develop with human society.
Drugs are an important part of medical resources, and they have also accompanied human history from ancient times to modern times, helping countless people overcome diseases, but where do drugs come from?
The early living environment of human beings is very harsh, in the process of hunting animals or picking plants to obtain food, it is inevitable that some poisons will be ingested by mistake, resulting in vomiting, coma, and even death and other poisoning phenomena, but sometimes it can make the original disease better or even healed.
Through repeated practice and summary of experience, people found that different animals and plants can have different effects on the human body, so the early development of medicinal animal and plant resources began.
How were landmark drugs discovered?
When it comes to landmark drugs, they belong to the bellwethers of their respective therapeutic fields and represent the efforts and achievements made by human beings in the field of medicine. The following two drugs must be familiar to you! Let's take a look
1. Penicillin
In the early 20th century, humans have not been able to find a drug to treat bacterial infections with few side effects, which means that in that era, once tuberculosis was developed, it would soon die. In order to change this situation, researchers have carried out long-term exploration, but the results are not satisfactory.
It wasn't until 1928 that Fleming went on vacation and forgot to grow bacteria in a petri dish in the lab. Three weeks later, when he returned to the lab, he noticed a clump of turquoise mold growing in a Staphylococcus aureus Petri dish that had been in accidental contact with air. He immediately looked at it with a microscope and found that the staphylococcus colonies around the mold had been dissolved. This means that some secretion of the mold inhibits Staphylococcus. Subsequent identifications showed that the above mold was penicillium, and Fleming called the bacteriostatic substance it secreted as penicillin.
In May 1953, China's first domestic penicillin was born, unveiling the history of antibiotic production in China.
2. Aspirin
Aspirin has been on the stage of history since very early.
The earliest mention of a herb, willow bark, was mentioned in ancient Egyptian papyrus, and its key ingredient was aspirin, which came to be known as the "elixir". In the Mainland Han Dynasty", the "Shennong Materia Medica" also records that "the roots, skins, branches and leaves of the willow can be used in medicine, and have the effect of expectorant, clearing heat and detoxification, and diuresis and windproof".
In 1828, French pharmacists and Italian chemists successfully isolated and purified the active ingredient salicylate from willow bark. Because of its sour taste, people usually call it salicylic acid.
Until 1897, when the father of the German chemist Felix Hoffmann took salicylic acid to treat rheumatism, he complained of its strong taste and side effects, so Hoffman invented acetylsalicylic acid, which is now aspirin.
The emergence of penicillin has ushered in a new era of treating diseases with antibiotics; the appearance of aspirin in many fields such as anti-cancer, hypoglycemic, anti-aging, and Alzheimer's disease has research value.
The increase in the types of drugs has led to the irrational use of drugs
With the progress of human understanding of diseases, the variety of diseases has increased; at the same time, with the vigorous development of the pharmaceutical industry, a large number of new drugs have sprung out. The continuous introduction of new drugs and the continuous increase in the variety of drugs have also brought better and more choices for disease treatment, but the phenomenon of irrational use of drugs and the occurrence of adverse reactions have also increased.
According to a survey data by the World Health Organization, nearly 1/3 of the world's patients die of irrational drug use every year, rather than the disease itself; the proportion of hospitalized patients with adverse drug reactions due to irrational use is 10% to 20%, of which 5% of patients die due to serious adverse drug reactions.
Reasons for irrational medication may be:
1
There are certain limitations to drug information and treatment experience;
2
Do not have a deep understanding of the pharmacology and efficacy of some new drugs;
3
For the detailed description of drug authorities, drug compatibility contraindications, interactions, etc., no suitable learning tools have been found.
How to use drugs rationally?
In 2020, the National Clinical Safety Drug Monitoring Network received 15 849 reports of medication errors (ME) from 255 hospitals in 24 provincial-level administrative regions across the country. The number of hospitals reporting ME increased by 8.97% compared with 2019 (234) and the number of reported ME cases increased by 5.27% compared with 2019 (15 056 cases).
Medication errors can cause considerable harm to patients, which may lead to increased morbidity and hospitalization rates, increase medical costs, and seriously lead to death.
For clinicians, it is not only necessary to diagnose, identify and formulate treatment plans for the patient's complex diseases, but also to grasp the medication information of each drug to ensure rational medication!
There are thousands of drugs, how to remember so much drug information?
If you don't rely on memory, what about looking up information?
Where can I quickly check drug instructions?
Through which channel can you preemptively know the drug information of new drugs?
The compatibility of drugs is too contraindicated and easy to be confused, where can you quickly query?
In fact, it is not difficult to grasp drug information quickly and easily. Secretly tell you that Xiaobian has recently been using the medication helper - the [Medication] module of the Medical Pulse APP!
This small helper can not only track the progress of new drugs and summarize massive drug data, but also gather clinical drug experience and help clinical safe and rational use.
1. Massive drug information: more than 30,000 authoritative manufacturers' drug instructions, data determine strength
2. Clinical drug review: more than 100,000 drug interactions, compatibility contraindications, etc., the drug is safe and reasonable
3. Authoritative diagnosis and treatment guidelines: more than 11,000 professional clinical diagnosis and treatment guidelines, more assured decision-making
4. Practical small functions: medical calculation formulas, hand-clapping drug information, drug topics, etc
For clinicians, it can solve the problem of clinical medication! For novice doctors, no longer have to fear the director's "life-threatening" serial questions!
Outside! Now there is a new version of the [Medication] module of the Medical Pulse App! Let's take a look at what new features have been added
1. Add the type of medication instructions to the list page, search, collection, and browsing history.
2. The medication instructions and medication instructions are revised to support the payment content of drug members; the membership center increases the number of drug members.
3. Added article hot list content.
The following xiaobian will provide the way to enter the [medication] channel of the medical pulse app: