Insomnia is now the most commonly suffered from a problem, there are caused by diseases, there are also psychological causes, long-term insomnia, for work, life have a great impact, clinically commonly used to treat insomnia drugs, Xiaobian for everyone to sort out several commonly used, their respective roles, use attention, adverse reactions, for your reference!
Anxiety, insomnia
Escolam
Principle of action:
Eszolam belongs to the benzodiazepine sedative hypnotics, according to the dose, can have anxiolytic, sedative hypnosis, anticonvulsant, relax muscles and other effects, the principle is to enhance the γ - aminobutyric acid can neurotransmission function and synaptic inhibition effect, γ - aminobutyric acid acts on the γ - aminobutyric acid a receptor, the cell membrane chloride channel is open, chloride ion reflux, so that the nerve cell membrane hyperpolarization, the central inhibitory effect.
Applications:
Has anxiolytic, hypnotic, sedative effects. It can also be used for anxiety disorders and can also be used for panic and insomnia.
Adverse reactions:
(1) Continuous use will cause dizziness, drowsiness, fatigue and other reactions.
(2) Overdose can cause acute poisoning, causing coma and respiratory depression.
(3) Long-term use will be tolerated, and long-term use will be dependent and addictive.
Use Caution:
(1) Glaucoma, myasthenia gravis, pregnant women are contraindicated during lactation.
(2) After taking it for a long time, the drug should be gradually stopped to avoid withdrawal reactions (insomnia, anxiety, agitation, tremor)
(3) Avoid driving, drinking alcohol, and manipulating machines during medication.
Eszolam tablets
Oshazepan
Oxazepam is also a benzodiazepine sedative hypnotic, with a mechanism of action similar to esazolam.
There are anticonvulsants, anti-epileptic, anxiolytic, sedative, hypnotic, central skeletal muscle relaxation. It is used for short-term relief of anxiety, tension, agitation, and can also be used for hypnosis, anxiety accompanied by mental depression.
(1) Drowsiness, dizziness, fatigue and other adverse reactions.
(2) Large doses can produce ataxia, tremor.
(3) Individual patients may experience excitement, polyglottalism, sleep disorders and even hallucinations, and the symptoms disappear after stopping the drug.
(4) There is addiction
(1) Pregnant women, lactating, < 6 years old should not be used.
(2) Long-term application, there will be withdrawal symptoms after discontinuation, and the drug should be stopped slowly.
(3) Combined with hypertension drugs and diuretic antihypertensive drugs, it can enhance the antihypertensive effect and cause hypotension.
Oxazepam tablets
Zopiclone
Zopiclone belongs to the non-benzodiazepine sedative hypnotics, because of the long-term use of benzodiazepines (zepam), the γ - aminobutyric acid A receptor activity will decrease, drug resistance and dependence, as well as serious drug discontinuation reaction, so non-benzodiazepines have become the mainstream of sedative hypnotics.
It can shorten the time to fall asleep, improve the quality of sleep, have a hypnotic effect, and be used for insomnia.
Drowsiness, dry mouth, muscle weakness, forgetfulness, drunkenness, headache and stomach pain.
(1) Severe hepatic insufficiency, pregnant women, lactating, children and patients with myasthenia gravis are contraindicated. Mechanical operators, drivers, and the elderly should use with caution.
(2) If the drug is suddenly stopped for a long time, there will be a withdrawal reaction, so the withdrawal of the drug needs to be reduced step by step.
(3) Avoid alcohol during medication.
Zopiclone tablets