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Eating grapefruit causes hypotension? Who can't eat grapefruit?

author:Xiaomi yarn ball

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hi! Hello life-loving friends.

I am Xiaomi Yarn Ball, thank you for continuing to lock my channel, let's work together for life force.

Today I received a patient who was dizzy and chest tight because of eating grapefruit, and my blood pressure was only 90/55. According to the patient, she had a history of high blood pressure and began to feel well after eating two grapefruits. Dizziness, chest tightness, panic, and pallor are typical symptoms of hypotension.

Eating grapefruit causes hypotension? Who can't eat grapefruit?

You must be wondering, how can eating grapefruit cause low blood pressure?

Recently, it is the harvest season of citrus fruits such as grapefruit, oranges, and oranges, and patients often ask: Doctor, I heard that eating grapefruit will be fatal, is it true?

This statement is not accurate, and it is not very strict to say that eating grapefruit causes low blood pressure. The precise reason is that eating grapefruit, that is, grapefruit, can cause blood pressure to be too low in hypertensive patients taking certain antihypertensive drugs.

We all know that drugs are mainly metabolized in the liver. Grapefruit contains a large amount of furan coumarin, which will irreversibly inhibit the activity of a liver drug enzyme, resulting in prolonged drug metabolism time, so that the drug accumulates in the body, and increases the body's absorption of the drug, resulting in drug overdose and poisoning. That is to say, grapefruit will enhance the efficacy of antihypertensive drugs, causing side effects of drug overdose.

Eating grapefruit causes hypotension? Who can't eat grapefruit?

According to research, the antihypertensive drugs that will have adverse reactions with grapefruit are mainly horizons, such as nifedipine, amlodipine, felodipine, and there are lol, such as propranolol, metoprolol tartrate, etc., as well as losartan, ilapril and the like. There are elderly people at home who take these antihypertensive drugs, we must pay more attention.

In addition, studies have shown that grapefruit will also have adverse reactions with some lipid-lowering drugs and drugs for the treatment of heart disease, such as simvastatin, amiodarone and so on. Therefore, if you are taking medicine, it is best not to eat grapefruit. Some drug labels will state that the drug should be avoided with grapefruit.

Eating grapefruit causes hypotension? Who can't eat grapefruit?

Speaking of this, some people will open their minds and say: grapefruit will increase the effect of the drug, so can I eat more grapefruit and take less medicine? This kind of thinking is as unreliable as the article "Eating more of this fruit can lower blood pressure".

Regardless of the dose to talk about toxicity, it is all hooliganism. 240ml of grapefruit juice can have an effect on the blood concentration of the drug, while 240ml is almost the size of a grapefruit. In other words, eating a grapefruit will increase the efficacy of antihypertensive drugs. But this effect is unstable. You yourself have no way to figure out how much grapefruit you eat to achieve the effect of lowering blood pressure, and it will not cause drug poisoning. Therefore, for the sake of safety, it is recommended that you do not try it easily. Besides, the market price of grapefruit is not cheap, sometimes a grapefruit is much more expensive than a piece of antihypertensive medicine, why bother.

Eating grapefruit causes hypotension? Who can't eat grapefruit?

A small partner asked, after taking the medicine, can you eat grapefruit every once in a while? The answer is: No. Because the activity of grapefruit in the body lasts for 72 hours, and the medicine is taken every day. Therefore, during the period of taking the drug, it is not recommended to eat grapefruit.

Can you eat other ordinary grapefruit, oranges, and oranges when taking medicine? Citrus fruits all contain furancoumarin, but are much lower than grapefruit. So, if you really want to eat, eat less.

If you accidentally have low blood pressure, don't be too nervous. The patient should be immediately placed on a flat bed, drinking more hot water, and replenishing blood volume. Then urgently go to the hospital for treatment.

Okay, that's it for today. I hope that while enjoying the delicious fruit, you can also maintain your health.

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