1.0 Can ulcerative colitis become cancerous?
Tao Wenhui, chief physician of the Department of Internal Medicine of Zhongnan Hospital of Wuhan University, pointed out that if ulcerative colitis has been ill for more than 5 years, colonoscopy should be followed up and screened for cancer, and the carcinogenesis rate in 10 years is 2%, and the carcinogenesis rate in 20 years is about 8%. This is because the intestinal flora structure of patients with ulcerative colitis has deteriorated, the microecology is seriously dysbalanced, the harmful bacteria have an absolute advantage, and the beneficial bacteria are absolutely disadvantaged, and the bacterial membrane barrier built by the beneficial bacteria to protect the intestinal mucosa disappears, and the ulcer surface of the colon is directly exposed to the intestine, and it is always subject to the phagocytosis of harmful microorganisms such as harmful bacteria, viruses, parasites, pathogens, protozoa and the stimulation of their secretion of toxins Over time, it will ulcerate, erosive, bleed, and develop into ulcerative colitis; free radicals will also attack normal cells and become cancer cells, and over time, repeated attacks, polyps, and even cancer. Therefore, enteritis is no trivial matter, and it is afraid of becoming cancer if it drags on for a long time!
2.0 Why is ulcerative colitis protracted and recurring?
Wang Xuemei, chief physician of the Department of Gastroenterology of Peking University People's Hospital, pointed out that the cause of ulcerative colitis (UC) is currently unclear, and it is generally believed that it is related to heredity, infection, dietary structure, lifestyle, autoimmunity, Mental stress and other factors, clinical treatment is mainly based on drug anti-inflammatory, to quickly control symptoms, to relieve the pain of patients, it is often difficult to restore intestinal microecological health and repair the bacterial membrane barrier from the root, once the drug is stopped, the protection of beneficial bacteria and bacterial membrane barrier is lost, after a period of time, harmful bacteria will come back and recur as before. In addition, factors such as patients stopping drugs on their own, changing drugs indiscriminately, bad mood, incorrect diet, and incorrect lifestyle are also the main reasons for the prolongation and recurrence of UC.
3.0 If Brother Hua Tuo is reincarnated, he may strangle all enteritis in the cradle!
When asked about the medical skills of the three brothers, Hua Tuo said: "The eldest brother Hua Feng has the highest medical skills, and the treatment of the disease before the onset of the disease spends the least amount of money, and the patient is not guilty, and only needs simple cooperation, but the general people are not in a hurry, do not believe or want to spend money on the treatment of the disease, so the eldest brother's medical skills are only known to the family." The second brother Warsaw medical skills are secondary, the treatment of the disease at the beginning of the disease, the patient needs to actively cooperate, not only to spend a lot of money, but also the patient suffers, but because the beginning of the disease is mild, the right medicine, the effect is very fast, relieve the pain, the general people think that he can only treat a slight disease, the reputation is only dedicated to the hometown. Hua Tuo's own medical skills are the worst, when the patient is seriously ill, the patient is very painful, the condition is easy to recur, and the money spent is the most, I use the medicine more violently, the patient needs to be highly cooperative, or use surgery to treat, sometimes I can come back to life, so many people think that I have excellent medical skills, and my reputation spreads all over the country. ”
The world's top academic journal "Nature Reviews Microbiology" published an article: intestinal probiotics play a pivotal role in human health: it controls 70% of the body's immunity, eliminates 80% of toxins, digests and absorbs 95% of nutrients, and is the connector of the entire metabolic system of the human body. All enteritis begins with the dysbiosis of the intestinal microbiota, the deterioration of the microbiota structure and the disappearance of the bacterial membrane barrier, and finally the intestinal microbiota is restored to balance, the microbiota structure is improved, and the bacterial membrane barrier is repaired.
3.1 Enlightenment of Hua Tuo's preventive treatment: improve the structure of intestinal flora and restore the balance of microecology.
In the early stage of mild imbalance of human intestinal flora, beneficial bacteria account for 50%~70%, but only slightly feel unwell, such as: constipation, occasional abdominal pain, diarrhea, diarrhea, unformed stool, increased stool, bad breath, abdominal distention, bowel sound, fart, rough skin and other symptoms, at this time, the bacterial membrane barrier has not disappeared, the intestinal mucosa has not appeared hyperemia, edema and other inflammatory reactions, in the pre-disease stage or intestinal hypersensitivity state, including the early stage of irritable bowel syndrome, often ignored, Afraid of trouble, or unwilling to spend money, thinking that it is good to endure and procrastinate, it is precisely this period is the best opportunity to quickly recover health, supplement Huojun No. 1 probiotics for 1 to 3 months, most of them can restore to the healthy balance of intestinal microecology, and prevent enteritis in the first place.
Professor Li Jingnan from the Department of Gastroenterology of Peking Union Medical College Hospital pointed out that intestinal flora imbalance often leads to diarrhea, constipation and other digestive tract pathologies. In addition, with the deepening of research on intestinal dysbiosis, it has been found that intestinal dysbiosis is related to irritable bowel syndrome, inflammatory bowel disease, liver disease, pancreatitis, diabetes, hypertension, obesity, dyslipidemia, immune diseases, and even autism, Alzheimer's disease and other diseases.
3.2 Enlightenment of Hua Tuo's second brother in the treatment of the initial disease: improve the structure of intestinal flora and restore the balance of microecology.
Once diagnosed as enteritis, it enters the middle stage of moderate imbalance of intestinal flora, beneficial bacteria account for 20% ~ 50%, the bacterial membrane barrier has not completely disappeared, and the gradually growing harmful bacteria and their secreted toxins begin to damage the intestinal mucosa and appear inflammatory reactions such as congestion and edema, sometimes infection with bacteria and viruses, dietary stimulation, mental stress and other factors will induce or aggravate this inflammatory reaction, that is, ordinary enteritis, colitis or irritable bowel syndrome, the patient has frequent abdominal pain, diarrhea, mucus stool, If you have a lot of stools, you will go to the doctor for treatment, if your body is very painful and affects your work and life. At this stage, adhere to systematic and standardized drug treatment, healthy dietary structure, lifestyle and psychological and emotional health management, and cooperate with the supplement of probiotic "Huojun No. 1" for enteritis for 2 to 4 months to restore the healthy balance of intestinal microecology, repair the bacterial membrane barrier, and prevent further development of ulcerative colitis.
Common enteritis, including specific colitis, can generally be cured with prompt treatment and the right cause. For example, in infectious colitis, the infected microorganisms are eliminated, and the intestinal flora is restored to a healthy balance, and the colitis is cured. Ischemic colitis can be cured by replacing blood volume and treating it with surgery. Pseudomembranous colitis can be cured as long as the healthy balance of intestinal flora is restored and Clostridium difficile toxins are resolved.
3.3 Hua Tuo's Enlightenment for Treating Serious Illnesses: "Five Troikas" Pay equal attention, and the collapse embarks on the road to recovery!
Once ulcerative colitis is diagnosed, it means that in the later stage of serious intestinal bacterial imbalance, the bacterial membrane barrier disappears completely, harmful bacteria account for the absolute upper hand, and the beneficial bacteria are less than 20%, and the damaged surface of the intestinal mucosa is engulfed by harmful microorganisms, toxin stimulation, fecal friction, free radical attack, etc., and the inflammatory reaction is strong, with ulcers, erosions, bleeding, stool mucus and bloody stool, abdominal pain, diarrhea, more frequent stools, constipation and diarrhea alternately, anal distention, Some patients will also have fever, the disease is prolonged and difficult to heal, recurring, the condition is very painful, the mental pressure is high, and the severe disease requires hospitalization. At this stage, we must adhere to the five troikas of "systematic and standardized drug treatment for more than 1 to 3 months, supplementation of the special formula probiotic "Huojun No. 1" for ulcerative colitis for more than 3 to 6 months, and lifelong healthy diet, lifestyle and psychological and emotional health management, so that the ulcer can be reversed and re-embark on the road to recovery. Don't leave anything to chance, beware of cancer overnight.
According to the data analysis of users of Jingdong Huojun No. 1 official flagship store: about 60% of the purchases of Huojun No. 1 for ulcerative colitis, about 30% of the purchases of Huojun No. 1 for common enteritis and irritable bowel syndrome, and less than 10% for intestinal flora improvement and preventive health care, indicating that the self-care awareness of the majority of users still needs to be strengthened to strangle all enteritis in the cradle.
4.0 Related Links——
The "five troikas" are equally important, ulcerative colitis and Crohn's self-healing are not dreams!
Ulcerative colitis and Crohn are also known as inflammatory bowel disease, the cause of which is unknown, but the six major triggers have been clear, clinical studies have found that it is closely related to genetic factors, infection factors, mental factors, autoimmune factors, dietary factors, living environment and other factors, the five troika theory is based on the five major triggers in addition to genetic factors, eliminating all factors that may induce or aggravate inflammatory bowel disease, the "five troika" pay equal attention, ulcerative colitis, Crohn self-healing is not a dream!
4.1 The first carriage: follow the doctor's instructions and adhere to the systematic and standardized treatment of drugs
Although the intestinal microbiota plays a very important role in the pathogenesis, treatment, prevention and management of inflammatory bowel disease, the role of drug therapy is essential during inflammatory attacks, and it is also the most effective and direct solution to prevent exacerbations. Drugs commonly used in ulcerative colitis include aminosalicylic acid preparations (sulfasalazine, mesalazine), hormones (prednisone, budenide), immunologic agents (cyclosporine, thiopylatene), and if none of these three drugs are controlled, the biologic infliximab may be used. Drugs have strong toxic side effects, drug resistance and dependence, and the dose, course of treatment and method of taking are strictly regulated, which must be used under the prescription of the hospital doctor, and cannot be used or discontinued at will.
4.2 The second carriage: self-help, adhere to the intestinal flora regulation of specific probiotics
There are thousands of probiotics, but only specific probiotics have a specific role in improving the structure of the inflammatory intestinal disease flora, the top star strain is Lactobacillus reuteri JYLB-291, which has obtained the Chinese invention patent No. ZL 2021 1 1566079.0, the patent details publicize that the invention patent is true and effective, and the total effective rate can reach up to 95.7% for ulcerative colitis causing fecal mucosal pus and blood, abdominal pain, increased stool frequency, loose stool, etc., and the functional test results are:
Secondly, the star strain of Lactobacillus casei L.Casei21 also has a prominent role in regulating the intestinal microbiota structure of IBD patients, and the conclusion of Baidu academic literature "Exploring the Effect of Lactobacillus casei combined with conventional treatment on the short-term outcome of ulcerative colitis" concludes that Lactobacillus casei combined with conventional treatment can effectively treat ulcerative colitis, significantly alleviate the clinical symptoms of patients, and has high safety, which is worthy of clinical reference. The strain obtained the Chinese invention patent No. ZL 2021 1 0242478.5, and the patent details were publicized for abdominal pain, diarrhea, frequent bowel movements, and lukewarm limbs caused by enteritis, with a total effective rate of up to 92% in 30 days, and the functional test results were:
Professor Nie Shaoping of Nanchang University published "Bifidobacterium longum relieves colitis: the influence of different intestinal flora backgrounds" in the Journal of Food Science, which pointed out that Bifidobacterium longum may be an effective treatment or adjuvant treatment for ulcerative colitis. Enteritis patients produce a large number of free radicals in their bodies every day, free radicals are the source of all diseases, one of the main culprits of aging and tumors, free radicals attack normal immune cells to make it "abnormal", and then attack intestinal mucosal cells, which is one of the culprits of autoimmune diseases. The star strain of Bifidobacterium longum JBLC-141 enhances the function of eliminating excess free radicals in the body, prevents the loss of free radicals to the body's cells, and can also play a certain protective role in cell oxidative damage and relieve the body's fatigue, and has obtained the Chinese invention patent number ZL 2021 1 0227019.X.
According to the statistics of Taobao Huojun No. 1 official enterprise store, IBD users insist on paying equal attention to the five troikas, and more than 90% of IBD users can embark on the road to recovery after taking Huojun No. 1 to regulate the intestinal flora structure for 3 to 6 months.
4.3 The third carriage: self-confidence, adhere to mental stress and health management
According to statistics, the overall prevalence of depressive symptoms and anxiety symptoms in adult IBD patients ranged from 21% to 25.2%, and the overall prevalence of anxiety symptoms ranged from 19.1% to 35.1%. The prevalence of IBD with depressive and anxiety states in children was 15% and 16.4%, respectively, and the prevalence of diagnosed depression and anxiety disorders was 3.4% and 4.2%, respectively.
David Perlmatt, MD, revealed in "Microbiota Brain" that the intestinal microbiota participates in the regulation of the gastrointestinal nervous system, and acts on the brain through the brain-gut axis, which is interconnected, that is, long-term mental stress and unhealthy emotions will lead to frequent and extreme changes in the structure of the intestinal flora, inducing IBD; Supplementing with specific probiotics (Huojun No. 1) acts on the regulation of gut microbes and helps to alleviate this mental stress conduction. However, it is essential for IBD patients to self-regulate or use psychological counselors to release mental pressure and eliminate anxiety, depression, irritability, doubt and other emotional activities.
4.4 The fourth carriage: self-discipline, adhere to the healthy management of dietary structure
The journal Nat RevGastroenterol Hepatol published "The role of diet in the aetiopathogenesis of inflammatory bowel disease", which explores the relationship between diet and the risk of inflammatory bowel disease from epidemiology, gene-environment interactions, microbial and animal studies. Primary outcomes include: Western-style diet (red meat, processed foods, refined sugars, saturated fats) is associated with an increased risk of inflammatory bowel disease, possible mechanisms of diet leading to inflammatory bowel disease, including causing intestinal dysbiosis, disrupting intestinal barrier function, altering the ratio of pro-inflammatory Th17 cells to regulatory T cells (Tregs), eating large amounts of fruits and vegetables, The Mediterranean diet, characterized by whole grains and seafood, can increase the diversity of intestinal flora, maintain intact intestinal barrier function, and balance the ratio of Th17 cells to Treg; some prospective studies have found that linoleic acid and heme iron are associated with an increased risk of IBD, and DHA, dietary fiber, zinc, potassium, milk, etc. are associated with a reduced risk of IBD.
Principles of healthy management of the dietary structure of IBD patients: (1) Mainly warm, avoid eating raw and cold food, and avoid irritating the intestinal mucosa. (2) Mainly liquid food, such as porridge, millet porridge, avoid greasy and indigestible food, increase the burden on the stomach. (3) The diet should be as light as possible, avoid spicy and irritating food, aggravate congestion and inflammation, and poor discharge. (4) Avoid gas-producing foods that cause discomfort such as abdominal pain. (5) Avoid rough food, which may stimulate gastrointestinal peristalsis and increase the digestive burden of the intestines. (6) Avoid seafood and avoid some foreign proteins that are easy to cause allergies and aggravate inflammatory reactions. (7) Avoid foods that promote excretion and lubricate the intestines, as well as foods containing lactose. (8) It is forbidden to eat overnight food, stale or out-of-season food, too salty food and pickled products. (9) Avoid overeating, which will cause gastrointestinal disorders.
4.5 The Fifth Carriage: Adhere to lifestyle health management
Lifestyle westernization, characterized by unhealthy eating habits and reduced physical activity, is not only associated with an increased incidence and prevalence of inflammatory bowel disease (IBD), but may also affect the course of the disease in patients with confirmed IBD. In addition to medication, many people with IBD seek supportive and adjunctive therapies. They often consult their doctors for advice on diet and lifestyle to improve or even cure the disease. Several studies have shown that various lifestyle factors, including diet and physical activity, play an impact on the course of the disease. A healthy lifestyle may help maintain remission and improve health-related quality of life (HRQoL).
Healthy lifestyle management includes: (1) regular healthy diet, regular and quantitative meals, (2) regular work and rest time, do not stay up late, do not tired, go to bed early and get up early with lunch break, and maintain sufficient sleep; (3) appropriate exercise, do not sit and stand for a long time, do not do strenuous exercise, maintain physical strength, can walk or jog, tai chi or yoga, and rest in bed during bleeding; (4) keep the abdomen warm to prevent cold, prevent air conditioning in summer, and prevent body cold in winter. (5) Be calm, do more things that make you happy, and keep smiling. For example: chatting, reading books, planting flowers, etc.
(Author's statement: This article is for reference only)