3 proprietary Chinese medicines for coronary heart disease, cerebral infarction, lacunar cerebral infarction, and stroke sequelae:
1. Tongxinluo capsules
Tongxinluo capsules are composed of ginseng, leech, whole scorpion, earthen turtle, centipede, cicada molt, red peony, ice chips, sandalwood, frankincense, incense and sour jujube kernel. Ginseng is a royal medicine, so that qi and blood flow, accompanied by insect drugs (leeches, centipedes, whole scorpions, soil turtles, cicadas) to search for stasis, with red peony to activate blood and disperse stasis, ice chips aromatic tricks, the combination of various medicines, together play the effect of invigorating qi and activating blood, relieving spasms, relieving pain, and eliminating evil and restoration.
For coronary heart disease angina is a deficiency of heart qi, blood stasis obstruction, symptoms include chest tightness, tingling, colic, fixation, palpitations and sweating, shortness of breath, dark tongue or ecchymosis, fine pulse or knots. It is also used for qi deficiency and blood stasis obstructive stroke, the symptoms are half body failure or partial numbness, crooked mouth and tongue, and unfavorable speech.
Atherosclerosis is an important factor causing cardiovascular and cerebrovascular diseases and seriously endangers human health. Tongxinluo capsules play a role in preventing atherosclerosis through various mechanisms such as lipid regulation, anticoagulation, anti-inflammatory, antioxidant, improving blood rheology, protecting vascular endothelium, and stabilizing plaque. It has the triple protective effect of blood, blood vessels and heart. It is widely used in the treatment of atherosclerosis, coronary heart disease, myocardial infarction, cerebral infarction and other diseases. It also has good effects on sick sinus syndrome, heart failure, carotid atherosclerosis, hyperlipidemia, etc.
Modern pharmacological research has also found that the effect of Tongxinluo capsules on cardiovascular and cerebrovascular aspects is: expanding coronary arteries, increasing coronary blood supply, inhibiting resistance vascular hypertrophy, improving vasomotor function, reducing cerebral vascular resistance, without affecting blood pressure. At the same time, it can inhibit myocardial fibrosis, protect against myocardial ischemia-reperfusion injury, and inhibit ventricular remodeling. It can also significantly reduce the volume of cerebral infarction and improve the symptoms of nerve damage.
2. Capsule of Metalloxine
Geji Tongluo Capsule is a new type of new drug of traditional Chinese medicine developed and produced by the Institute of Medicinal Plants of the Chinese Academy of Medical Sciences and pharmaceutical companies, which has the effect of activating blood circulation and removing stasis. It is used for ischemic stroke in the recovery period of meridian stasis and obstruction of the vein, the symptoms are half body failure, crooked mouth and tongue, partial numbness, unfavorable language, dizziness, strong neck pain, etc. Atherosclerotic thrombotic cerebral infarction and lacunar cerebral infarction see the above symptoms.
Modern pharmacological studies have shown that the main active ingredient of Pueraria Tongluo capsules is Pueraria Total Flavonoids, an ethanol extract of Pueraria Mirifica, including puerarin, daidzein, daidzein glycosides, etc. It mainly plays the role of protecting nerves and anti-cerebral infarction by inhibiting the formation and progression of atherosclerotic plaques, removing the production of oxygen free radicals in the brain, inhibiting apoptosis of nerve cells, and anti-platelet aggregation.
Inhibit the formation and development of atherosclerotic plaques: Embolism caused by atherosclerosis and rupture of vulnerable plaques is the main pathogenesis of cerebral infarction, and is closely related to the occurrence, development, recurrence of the disease and the site of cerebral infarction. Pueraria total flavonoids effectively reduce the viscosity of blood, which is more obvious in pathological conditions, reduces platelet adhesion rate, improves plasminogen activity, and then inhibits the formation and development of atherosclerotic plaques.
Anti-oxidation and oxygen radical removal: Experiments have proved that Pueraria mirifica has strong antioxidant and oxygen radical removal capabilities, and achieves the purpose of reducing brain tissue damage by increasing the activity of superoxide dismutase, reducing malondialdehyde content, eliminating oxygen free radicals and anti-lipid oxidation. After cerebral infarction, the stimulation of ischemia and hypoxia leads to the normal metabolic imbalance of free radicals, on the one hand, a large number of free radicals accumulate, and the production of lipid peroxidation products malondialdehyde increases; On the other hand, the continuous consumption of superoxide dismutase significantly decreases, and the antioxidant damage capacity is weakened, which in turn causes damage to brain tissue and nerve cells.
Inhibition of apoptosis of nerve cells: apoptosis after cerebral infarction directly determines the number of nerve cell necrosis and the area of the infarct area. Therefore, timely and effective anti-apoptosis is expected to become an effective treatment for cerebral infarction. Pueraria total flavonoids increase the activity levels of glutathione peroxidase and superoxide dismutase, reduce the content of malondialdehyde, reduce the expression of the most important terminal shearing enzyme in the process of apoptosis, further reduce the degree of apoptosis of nerve cells, and exert brain protection.
3. Compound danshen drop pills
Compound danshen drop pills, composed of danshen, Panax notoginseng, ice chips three flavor medicine. Activate blood circulation and dissolve stasis, regulate qi and relieve pain. It is used for chest paralysis caused by Qi stasis and blood stasis, and the symptoms are chest tightness and tingling in the precordial area; Coronary heart disease angina pectoris see the above symptoms. It is used for stage I (mild) and stage II (moderate) non-proliferative diabetic retinopathy caused by type 2 diabetes mellitus caused by stagnation and blood stasis, dull complexion, fundus spot-like hemorrhage, purple tongue or petechiae, pulse or fineness.
According to the theory of traditional Chinese medicine, there is a synergistic and complementary effect after the combination of danshen and Panax notoginseng. As an adjuvant, ice chips can promote the entry of the active ingredients of Danshen Panax notoginseng into the body and tissues and organs, and have the effect of dilating coronary arteries and analgesic. Among them, the extract of danshen has anti-peroxidative damage, myocardial protection, improvement of myocardial energy metabolism, and anti-platelet aggregation. Panax notoginseng extract has anticoagulant, anti-inflammatory, inhibition of lipid deposition and antiplatelet aggregation.
Modern pharmacological studies have shown that compound danshen drop pills mainly have the following four pharmacological effects: (1) antioxidant, anti-inflammatory, protect vascular endothelial function, inhibit atheroplaque formation and endometrial hyperplasia. (2) Reduce myocardial oxygen consumption, improve energy metabolism, and protect myocardial cells. (3) Inhibit the adhesion and aggregation of platelets. (4) Improve microvascular circulation, and have good preventive and therapeutic effects on ischemia-reperfusion injury and microcirculation disorders caused by other causes.
Clinically, it is mainly used for: (1) long-term combination therapy on the basis of standardized treatment of patients with angina pectoris with coronary heart disease, which is also suitable for: inability to tolerate nitrates, low responsivity of platelets taking aspirin or clopidogrel, decreased exercise tolerance, perioperative PCI and asymptomatic myocardial ischemia, microvascular angina. (2) Chinese proprietary medicine emergency medicine for angina pectoris attacks. (3) On the basis of conventional treatment of diabetic patients, it is used as a combination drug for the prevention and treatment of vascular complications. #挑战30天在头条写日记 #
