【Subvert cognition! 】 Drinking coffee to prolong life by 24%? Japanese research team: The key lies in this substance.
Author: Time Pie Hebe (Co-Founder of Time Pie APP)
Source: Zhihu
The proven origin of coffee is from Ethiopia in eastern Africa, where legend has it that a shepherd who one day found his goat "dancing" after swallowing a red berry brought the story and the berries to a monk. The monk often needed to chant at night, and he tasted the berries half-believingly, not expecting it to help him stay awake all night.
This magical berries is also known as the "life-sustaining water" of the modern population. In order to stay focused and eliminate sleepiness, people often choose to drink a cup of coffee during the day. As the number of coffee drinkers grows, and the student party that writes papers in schools and the office workers who do projects in the company are almost everyone with a cup, what is the impact of long-term coffee drinking on the body?
In response to the magical power of small berries, scientists have not stopped the pace of research, and many studies have confirmed that drinking coffee can prevent cancer, diabetes, arteriosclerosis and other diseases. Just recently, a new study added new evidence to the health benefits of coffee.
First, the American research team: drinking coffee to enhance learning ability
The study, conducted by a team of researchers at Johns Hopkins University in the United States, found that long-term intake of caffeine can inhibit the expression of metabolically related proteins while upregulating protein levels. In other words, caffeine can make the brain perform better, greatly enhancing learning and cognitive abilities. The study has been published in the international journal JCI (Journal of Clinical Research).
The researchers conducted clinical trials in mice and divided them into two groups: the control group and the caffeine group. Long-term caffeine intake was observed to reduce histone acetylation of genes associated with metabolism in hippocampal tissue, meaning that the brains of mice in the caffeine group would perform better. To verify this effect, Professor Isabel Paiva, lead author of the study, used a water maze experiment to compare learning from two groups of mice. The results showed that the two groups of mice had essentially the same swimming speed, but on the third day of training, the caffeine group of mice needed to reach the finish point at a shorter distance.
In addition, the research team used RNA sequencing to compare and analyze the changes in gene expression after learning training in the two groups of mice. It was found that most of the gene expression changes were only in the case of caffeine intake + learning, whether it was up-regulation or down-regulation, and there were significant differences with the blank control group. Throughout the experiment, the mice in the caffeine group did not experience any discomfort, pain, or death.
After the physical and mental benefits of drinking coffee were verified, scientists were not satisfied with this, and then discovered the amazing effect that drinking coffee can prolong life!
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Full Text: Subvert cognition! Drinking coffee to prolong life by 24%? Japanese research team: The key lies in this substance - Zhihu
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