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The weather was rainy

Normal body temperature

Mood up

Xiaomei (pseudonym) has been very distressed recently, do not know what the reason, in a few months the weight increased by nearly 10 pounds, pants waistline directly larger than 2 yards. She got a fitness card, hired a personal trainer, and went to the nutrition department of the hospital to prescribe nutritional interventions, but her body still became fat like a balloon.

Xiaomei was worried: "I have recently gained a lot of weight, my face is also swollen, my stomach is still stretch marks like others who are pregnant, I have tried my best to control my diet, and I am also desperately exercising, but I can't reduce it, and I am sad to die!" The nutritionist already has a guess in his mind: "There may be other reasons for your fatness, it is recommended that you check the endocrine hormones." ”

So Xiaomei was transferred to the outpatient clinic of Wang Yongjian, chief physician of the Department of Endocrinology of the Second Hospital of Zhejiang University.

On Day 2, Xiaomei's test results showed that cortisol and adrenocorticotropic hormone were high. At the suggestion of Dr. Wang Yongjian, Xiaomei was admitted to the endocrinology ward, and through a comprehensive and meticulous examination, she was diagnosed with a disease caused by pituitary tumor - "Cushing's disease".

After that, Xiaomei smoothly transferred to the neurosurgery department for minimally invasive pituitary tumor resection, and continued to follow up regularly in the endocrinology department after the operation. When Xiaomei appeared in Dr. Wang Yongjian's clinic again 3 months later, she had already changed drastically, and the fat girl with the original round face had slimmed down so beautifully.

Why look for reasons before losing weight?

Obesity is a complex disease, in which many endocrine-related hormone secretion disorders can cause abnormal weight gain, such as corticosteroids, thyroid hormones, growth hormones, insulin, etc.

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If the original hormone disorder is not solved, then even if you exercise and diet hard every day, it may be half the work, how to fight can not win the weight of the rub, long-term cardiovascular disease, diabetes, hypertension, osteoporosis, fatty liver and other complications.

What is the pituitary gland?

The pituitary gland is the headquarters of the human endocrine gland, which sits at the base of the skull and is responsible for secreting a variety of hormones. These hormones play an important role in metabolism, growth, development and reproduction.

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What is a pituitary tumor?

Pituitary tumors are a group of tumors that originate in the glandular pituitary gland, the neuropituitary gland, and the residual squamous epithelial cells of the embryonic craniopharyngeal sac. It accounts for 10%-15% of the number of intracranial tumors, and most of them are benign. It can manifest as symptoms of tumor compression (eg, headache, vision loss, etc.) and symptoms of excessive or insufficient hormone secretion.

Pituitary tumors are divided into functional and non-functional adenomas according to whether they secrete hormones or not. Common functional pituitary tumors are—

Prolactinoma

May present with amenorrhea, galactorrhea, infertility (childbearing), and hyperprolactinemia.

Growth hormone tumors

Underage patients can develop hypergrowth and even develop into giants. The onset of disease in adulthood is mostly a manifestation of acromegaly. Such as changes in the face, the lengthening of the face, the enlargement of the head, the large and protrusion of the lower jaw, the thickness of the nose and the thick lips, and the hypertrophy of the hands and feet.

Adrenocorticotropic hormone tumors

Also known as Cushing's disease.

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Typical patients have obvious centripetal obesity; full moon face, buffalo back, fat pad on the collarbone, fat can also accumulate in the chest, abdomen, buttocks of the trunk, relatively thin limbs, combined with atherosclerosis, blood glucose lipids and blood pressure abnormalities and other manifestations.

Treatment of pituitary tumors

The treatment of pituitary tumors is mainly based on surgery, drugs, and radiation therapy. Surgical treatment is the mainstay of treatment for most pituitary tumors. Pituitary tumor treatment goals: to restore the normal function of the pituitary gland, to relieve tumor compression or hormone secretion problems. Treatment of pituitary tumors requires multidisciplinary collaboration and long-term follow-up management with a focus on endocrinology.

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With the cooperation of the Department of Endocrinology and Neurosurgery, Xiaomei successfully clarified the diagnosis and completed the operation in 1 week.

Here we also need to remind everyone that everyone's situation is different, and it is necessary for professional doctors to evaluate individually and even multidisciplinary teams to clarify the diagnosis and treatment plan.

The Endocrine Pituitary Tumor Clinic of the Second Hospital of Zhejiang University is the first pituitary disease specialist clinic in the field of endocrinology in Zhejiang Province.

Services: Diagnosis and preoperative management of pituitary tumor, endocrine hormone replacement therapy after pituitary tumor surgery, comprehensive management decision-making of pituitary tumor, referral of refractory pituitary tumor MDT, etc., full-cycle closed-loop clinical services from diagnosis, treatment to follow-up for patients with pituitary disease.

Recently, the Department of Endocrinology of the Second Hospital of Zhejiang University, together with the Department of Neurosurgery, Radiotherapy and the Department of Radiology, has carried out a joint outpatient clinic for pituitary diseases (click registration), mainly for patients with pituitary diseases, including the diagnosis of intractable diseases and the multidisciplinary treatment of refractory pituitary diseases.

On March 28 & April 1, the video number platform of Zhejiang University Second Hospital and Zhejiang Second Internet Hospital will invite Zhao Yiming, deputy chief physician of the Department of Endocrinology, and Cai Feng, deputy chief physician of neurosurgery, to talk about the popular science knowledge of "pituitary tumor", welcome to make an appointment to watch!

Text | Department of Endocrinology Zhao Yiming Liang Weiwei

Figure | Partly from the network

Audit | Chen Guozhong Wang Yongjian

Editor-in-charge | Zhu Junjun

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