▎ WuXi AppTec content team editor
Some fans guessed kidney failure, which is half right.
What the hell is going on? Let's see the truth.
The last issue of the truth review
Last time, Aunt Kang ate health care products of unknown origin for 1 month, appeared in "soy sauce urine" and body aches and weakness, and was admitted to the hospital - these are typical symptoms of rhabdomyolysis.
Image credit: 123RF
Sure enough, blood tests showed that her creatine kinase was more than 100 times higher than normal, and the transaminases equivalent was also very high, indicating that the kidney and liver function damage was obvious.
She was diagnosed with acute renal failure, rhabdomyolysis syndrome.
After being hospitalized for a period of time, Aunt Kang's limb weakness, muscle soreness and other symptoms finally disappeared, and liver and kidney function was gradually restored.
The doctor asked about the medical history, and the family was very suspicious of the problem of the "three noes" health care products.
After taking it to test, it turned out that there was a statin in it!
Doctors say it is a prescription drug that lowers blood lipids, but some patients may experience side effects such as rhabdomyolysis during taking the drug.
At the beginning, Aunt Kang herself suffers from the "three highs", that is, hypertension, diabetes and hyperlipidemia, and may also be taking other drugs.
And the health care products she ate illegally added prescription drugs, not labeled (even if labeled, health care products themselves are food, adulterated drug behavior is also illegal), and the specific dose is not determined at all, which is likely to lead to drug overdose or drug interaction.
She also eats health care products as medicine every day, which has led to serious consequences.
Popular science time
Statins are a class of lipid-lowering drugs, in addition to reducing triglycerides and total cholesterol, but also significantly reduce the mortality of stroke and myocardial infarction, which has a large amount of evidence-based medical evidence to prove its effectiveness and safety.
Therefore, it is very common for doctors to use this drug for patients with hyperlipidemia, as long as the medication is taken under the guidance of a doctor, it is necessary to observe closely during the medication and monitor the changes in the liver and kidney function of patients, which is generally fine.
However, in individual cases, some side effects may also occur, and occasionally elevated transaminases, but this is reversible.
Serious adverse reactions such as rhabdomyolysis are actually very rare.
Afraid to be afraid, some patients are in a hurry to go to the doctor, take medicine indiscriminately, and even do not know that they are "taking drugs".
Many unscrupulous merchants are desperate to take risks, worried that the pure "plant extract" will not give strength, and they will hurt the "strong medicine"——
Illegally adding prescription drugs to the "three noes" health care products, thinking that after the patient eats the "effect", it can attract more people to pay...
(Regarding the serious consequences of illegally adding prescription drugs, we have written an article before, recalling the poking of women with neck and back pain to massage, and multiple organ failure died after 1 month... |.) Truth Open)
Health care products belong to food, not drugs, and cannot publicize the therapeutic effect of diseases, which is called false publicity.
Some people listened and may not carry out standardized treatment, delaying the disease; and illegally adding drug ingredients is a further harm to people's lives.
If Aunt Kang was already taking lipid-lowering drugs and eating "plus medicine" health care products at the same time, it may lead to overdosional medication;
If Aunt Kang is still taking other drugs, statins may also interact with a variety of drugs, such as immunosuppressants, folic acid derivatives, niacin, gefirozil, erythromycin, etc.; may also interact with fruits such as grapefruit and grapefruit.
And in these cases, the incidence of rhabdomyolysis increases!
Rhabdomyolysis, it sounds like the muscles have "melted"?
In fact, the rhabdomyocyte membrane is completely destroyed, and the enzymes, myoglobin and other things inside "leak" out, and a large number of them enter the blood circulation.
Anatomy and histological specimens of mammalian rhabdomy muscle under the microscope (Image source: 123RF)
The process of "muscle dissolution" is a bit like the extra part of the "blood water" that comes out after we usually cook to thaw the frozen meat - in fact, this is not blood, it is myoglobin.
When the content of free myoglobin in plasma is too high and exceeds the processing capacity of the kidneys, it will appear in the urine. At first it was pink, and later it became brownish red or brown-black, so it was called "soy sauce urine".
Finally, I would like to advise you:
1. Do not buy "three noes" health care products of unknown origin! "Eating in the mouth" can enter the bloodstream faster and is more dangerous than external use. If there is any abnormality after eating, don't take any chances and seek medical attention in time.
2. Do not rely on health care products for treatment, go to the hospital when you are sick, and carry out timely and formal treatment.
3. Do not hide the disease and avoid the doctor, although the drug may also have side effects and adverse reactions, they are clearly written on the instructions, as long as you listen to the doctor, regular review is good, everything is controlled, all in control. Prolonged non-medication delays can lead to more serious and unpredictable consequences.