Dr. Dai Xue of Shanghai Tenth People's Hospital: The total length of the follicles is not large, have you considered these reasons?

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Column expert introduction

Dai Xue

Shanghai Tenth People's Hospital

Associate Physician, Center for Reproductive Medicine

He has rich clinical experience in gynecological endocrine diseases such as menstrual disorders, infertility, polycystic ovaries, premature ovarian failure, etc. It is unique for intractable diseases in infertility, such as advanced pregnancy, recurrent miscarriage, and hysteroscopic management.

Egg quality is a matter of successful pregnancy. The quality of the follicle determines the quality of the egg.

In fact, the relationship between eggs and follicles is a bit like grapes and grape seeds. Therefore, the quality of follicle development will also determine the quality of the egg.

If the follicle is stunted, cannot ovulate normally or the quality of the eggs released is not good, it will directly affect normal conception. Even if the pregnancy is successful, it is easy to have fetal arrest and miscarriage.

First, what do good follicles look like

Judging egg quality generally requires indirect speculation by observing the condition of the follicle.

The easiest and most intuitive way to assess follicle development is through ultrasound.

Generally speaking, when the follicle diameter reaches 18 to 28 mm, it is a "mature follicle", which is full in appearance, round or oval, and the inner wall is thin and clear, so that the "good follicle" is more likely to conceive after ovulation.

However, just as "there are no two identical leaves in the world", the diameter of the follicle when it matures and ovulates will vary from person to person and from person to person, some grow to 15mm, and some grow to 25mm or even larger.

Second, the diagnosis of follicular dysplasia

Clinical manifestations

Married for more than two years, or have a history of pregnancy and childbirth for more than two years, the couple lives together and has a normal sexual life, the spouse has normal reproductive function, and the person is not contraceptive and infertile. May be accompanied by clinical manifestations of menstrual disorders.

Basal body temperature

Measure the body temperature curve in a continuous unipolar type.

Cervical mucus

The rating is 4 to 7 points

B-ultrasound examination

Starting on the 11th day of the menstrual cycle, b ultrasound monitoring for more than 3 months without mature follicles (17 to 18 mm) or follicular atresia.

Estradiol (E), follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were measured below normal.

Note: The above are all necessary except for clinical manifestations.

3. What are the possible causes of follicular dysplasia?

1. Pituitary problems: common diseases that cause abnormal ovulation, including pituitary prolactinoma, hyperprolactinemia, etc., high prolactin levels can inhibit ovulation.

2. Hypothalamic nonovulation: primary organic factors, primary functional factors, secondary organic lesions, secondary functional factors.

3. Premature ovarian failure: early menstruation is normal, and even has a history of fertility, but then menstruation is rare until complete amenorrhea, because the follicles in the ovaries have been exhausted, it is impossible to use ovulation induction drugs to develop follicles, or although there are primitive follicles, there is no response to gonadotropins.

4. Polycystic ovary syndrome: Polycystic ovary syndrome is the most common cause of female non-ovulation. It is characterized by an increase in the size of the ovaries, multiple small follicles, but they do not mature, and drugs are needed to promote follicle development.

5. Luteal insufficiency: Insufficient luteal body can trigger the appearance of follicles that do not grow much, and injections can be given to promote their growth according to the doctor's advice.

6. Endocrine disorders: the more you want the baby, the more nervous the spirit, the endocrine will be affected, and you may fall into a vicious circle of more expectations and less fully manifested follicles.

IV. Conclusion

If the quality of the follicles is not up to standard, it is necessary to reflect on your daily behavior habits, minimize stress, maintain a good attitude, and balance nutrition and strengthen exercise in daily life. If you still can't get better, it is recommended to seek medical help as soon as possible.

This article is reproduced from Dr. Dai Xue's popular science article, the copyright belongs to Dr. Dai Xue, if there is any infringement, please contact Xiaobian to delete