The P3 laboratory of the Institute of Virology of the Chinese Center for Disease Control and Prevention is completely sealed at this time, the room is in a state of negative pressure, the researchers in the laboratory are all serious, they have been working in the laboratory for 4 hours continuously, today, the Institute of Viral Diseases received the first batch of specimens and quickly carried out gene sequencing and virus isolation, to figure out the gene sequence of the new crown virus, equivalent to deciphering the "new crown virus code", Wang Ke held this "chip" in his hand can detect the whole genome of more than ninety viruses. After generating massive amounts of short sequence data, the original genome sequence is restored.
"Ding-dong", Wang Ke took out the mineral water in the vending machine and drank it in a big gulp, he had not drunk water for 6 hours, and his face left a deep stranglehold due to wearing a mask for a long time. "Didi" He took out his mobile phone from his pocket to check the message: "Husband, are you going well over there?" Wang Ke gently pulled the corners of his mouth, and his expression was gentle, "I am very good, take care of myself and the baby." ”
"Is my sister-in-law okay?" Partner Liu Yifeng patted Wang Ke's shoulder, "You guys are really not easy, your sister-in-law is about to give birth, right?" Do you want to apply to the director to go back? "Thank you for your concern, now is the key moment of the development of the new crown virus vaccine, we have just made great progress, and then there is an urgent need to carry out a series of scientific research, including monitoring the mutation trend of the virus and exploring the pathogenic mechanism of the vaccine, whether the mutated virus is effective, at this time I must sacrifice the ego." "Brother, I really believe you!" After speaking, Wang Ke and Liu Yifeng wore 5 pounds of protective clothing and breathing devices and entered the laboratory.
Wang Ruolin touched his growing belly, then opened the drawer, took out the fetal heart rate detector, applied couplant on the probe, and then put it on the stomach to find the fetal heart, the familiar sound of the fetal heart beating sounded regularly, and the rate of 150 on the screen made Ruolin smile with peace of mind. Now more than 38 weeks, anxiously waiting before delivery, the fear of the unknown of delivery has made her live like a year, she got up and put on a mask, and today she is ready to go to the hospital for a maternity examination. On the way, she saw boxes containing milk powder, ventilators and other daily life and epidemic prevention supplies, driving through unmanned autonomous vehicles to the sealing and control management area. Carrying drones carrying pharmaceutical supplies, epidemic prevention delivery robots provide "the last 100 meters" delivery services for residents in home isolation. The epidemic has not only changed her family, allowing her and Wang Ke to get together less and more, but also changed the whole city, and I hope that everything will slowly get better.
"Why does China's vaccine research and development seem to be relatively slow, because in China because of the effective prevention and control, we have no way to do phase III clinical trials in China, because there are no patients, so phase III clinical trials can only be done abroad." Young people should dare to innovate, maintain enthusiasm, and create the future with dreams and passion. Chinese vaccines are effective against Indian strains, so feel free to inject them! A 19-year-old student volunteer, Huang Yu, watched Academician Zhong Nanshan on the big screen attend the 2021 graduation ceremony of ShanghaiTech University. He came to the base with his school bag on his back to test the vaccine, and Wang Ke was injecting Huang Yu, saying: "After the injection, you may have diarrhea symptoms, and you will feel tired for several days. He gently patted Huang Yu's shoulder, "Don't worry, other volunteers also have these symptoms in the first phase of clinical trials." ”
Huang Yu looked at Brother Wang Ke with wide eyes, "Brother, I am not afraid, the hardships I have suffered since childhood are much more difficult than this needle, and I want to develop vaccines like you in the future and do a handsome job." Looking at Huang Yu's radiant face, inexplicably moved, he smiled: "The handsome work you think is very hard, and it takes about 8 to 10 years for vaccines to move from research and development to production." R&D personnel should be in close contact with the virus, and they should repeatedly conduct experimental research and race against the virus. First of all, the virus strain should be isolated, just like choosing a "seed", you have to choose a good vaccine "seed"; then reproduce and cultivate, such as amplifying dozens of times, hundreds of times, etc., and then kill these live viruses, so that they lose infectivity and replication, but at the same time retain part of the function of stimulating the human body to produce immune responses, and finally become a vaccine through purification and other processes.
"Jingle Bells... Wang Ke's mobile phone ringtone interrupted him, "Hello, hello, I'm researcher Wang Ke, please speak." Huang Yu looked at Wang Ke's face and was thinking about what he had just said, when suddenly, Wang Ke's sudden expression pulled his thoughts back, "Brother, what's wrong?" "Yifeng, you help me take care of this place, I have an urgent matter to go out."
Wang Ke is running back to the research institute quickly, and the bad news on the phone has been echoing in his ears: your wife Wang Ruolin was found to be infected with the new crown vaccine, and now we have taken a comprehensive isolation and jointly managed by the department of infection, obstetrics, ICU and other related departments. Since the fetus in the womb is full-term, we recommend terminating the pregnancy as soon as possible and giving birth immediately with a procreative injection, which requires your consent. ”
When Wang Ke arrived at the director's office, the director was hanging up the phone, he looked at Wang Ke: "I have received a call from the hospital, your current mood I understand very well, but in this sensitive and critical period, you must be more rational, encourage your wife to cooperate with the hospital's examination and arrangement, rather than going to her side to bear the risk of possible infection, you are a very important member of our laboratory, I hope you stick to your post, I believe your wife will feel your heart." ”
It was nearly evening when he came out of the director's office, And Wang Ke sat down on a chair in the hall with his eyes closed, and his wife's smile echoed in his mind, "Ruolin, will you blame me for my choice?" A tear slowly slipped from the corner of his eye.
Ruolin has carried out a series of examinations in recent days, including chest imaging examination (chest CT examination radiation exposure dose is not enough to cause fetal malformations), when she learned that she was suffering from new crown pneumonia, she was discouraged, but Director Zhao Fen reminded that pregnant women are in a panic that is unfavorable to themselves and the fetus, and there are not many cases of serious situations caused by pregnant women due to new coronavirus disease, so she should not be overly anxious. Although it was really uncomfortable, Ruolin tried to control her emotions and was highly cooperative with the hospital's arrangements, and she only hoped that the baby would be born safely.
At exactly 12 o'clock, a syringe was pulled out of Ruolin's arm, and today the doctor gave her a stimulus injection, the chief physician and nurse were making preparations in an orderly manner, the clock on the wall passed minute by minute, the pain in the stomach gradually intensified, and the consciousness was blurred. At this point the nurse stopped giving birth to the needle. At this time, the pain is on average every 4 minutes. At 10:30 p.m., there was still no finger open, and Ruolin's face was already intertwined with sweat and tears, "Director, the patient is now breathing very hard," Nurse Zhang said anxiously. Director Liu personally gave Ruolin a tranquilizer, and Ruolin's brain instantly dizzy and began to sleep. "Director, the patient has been prescribed to ten fingers!" The head nurse said. "Push the woman to the delivery room right away." After 30 hours of pain in the opening finger of the induction needle, Ruolin's body has reached its limit, at this time the chief physician Zhao Fen immediately held her hand "Ruolin, Ruolin, the baby's head has been seen, come on, right, Wang Ke just called me, he is now waiting for your good news" Ruolin's nails pinched a deep mark on Zhao Fen's hand, Ruolin cried out loudly, in the last second when she was close to fainting, the baby's cry rushed into the eardrum, at this time Wang Ke and colleagues were applying high-throughput sequencing technology, Electron microscopy identified the first new crown virus isolation successfully! Everyone looked at each other for the first time, and silent joy was transmitted from the eyes. Ruolin cried with joy, "Baby, baby... Subsequently, the nurse immediately carried the newborn to the isolation room, and then closely observed the clinical manifestations of infection, during which time Ruolin was not allowed to breastfeed directly.
“
Recently, the Obstetrics and Gynecology Department of Union Hospital successfully delivered a baby boy with 7 pounds and 5 pairs for a pregnant woman infected with the new coronavirus pneumonia. The mother was in good condition after delivery, and the baby boy was in good health and free of infection. According to Zhao Fen, director of the Department of Obstetrics and Gynecology, pregnant women are special groups of people, and once infected, they need to pay special attention. Pregnant women infected with the new crown epidemic is a very special group of people, their physical function and immunity are not in a best state, the influence of high levels of estrogen and progesterone in the receptor, her upper respiratory tract mucosa thickening, mild congestion, edema, more prone to upper respiratory tract infections lead to breathing difficulties, this case of infection with new coronavirus pneumonia maternal vaginal delivery successful experience, for other hospitals in the country to carry out suspected or infected with the new coronavirus pneumonia pregnant women treatment has reference significance. In front of the TV set were countless pregnant women, and finally froze on Wang Ke's tearful face: "Wife, I'm sorry, I love you." ”
About the Author
Zhang Qingxiao, pen name Amy, planning director of Baizhan Lion Pictures, contracted screenwriter of Dadi Yinghao Film Company, contracted writer of 21st Century Publishing Company, douyin travel blogger, founder of Moqu Coffee, specializing in literary fiction, psychology, rhetoric, travel photography, graduate English and other fields.