Have you ever heard a 14-year-old cry?
Have you ever seen a 29-year-old doctor crying with trembling?
Perhaps these fragile aspects of human nature will not be easily revealed, but in the Infectious Disease Prevention Institute, the VCT consultation room happens almost every day.
In the doctor's opinion, the disease will always be cured, but in the patient's view, some diseases may mean regret for life.
Yes, the topic we are talking about today is still AIDS, a disease that lurks in temptation and can make you fall into the abyss.
<h1 class="pgc-h-arrow-right" data-track="8" > AIDS is not a terminal illness, but the fear it brings to people's psychology is stronger than all</h1>
Medicine is becoming more and more developed, and all doctors are telling you that AIDS can achieve a functional cure and return to normal people's lives.
But in the eyes of patients who have been infected with the disease, this sentence is how ridiculous and helpless.
They went through the window period and survived the fear period of waiting for the results of the test, but how many people stopped taking their medication.
Sometimes there is no hope but no willingness to give up health. AIDS blocking drugs really give patients a headache.
But Dr. Zen still wants to say from a medical point of view, antiretroviral drugs must be taken, which is the best way for us to regain our lives.
<h1 class="pgc-h-arrow-right" data-track="15" > if the results cannot be reversed, then you must be clear about the significance of antiretroviral therapy</h1>
Maybe others will look at you coldly, but believe that at least the doctor will not abandon you.
Antiretroviral drugs are to inhibit the infinite replication of the virus in the body, so that the virus can not replicate, stop the attack on the immune system, when the virus particles are zero, naturally achieve health. It also avoids the occurrence of various complications and greatly reduces the problem of morbidity and mortality rate.
To explain the effects of the drug in more detail, Dr. Toh briefly introduces the effects of antiretroviral drugs below.
At present, the anti-retroviral drugs in our country mainly include nucleoside reverse transcriptase inhibitor NRTIs, non-nucleoside reverse transcriptase inhibitors NNRTIs, protease inhibitors PIs, integrase chain transfer inhibitors INSTIs, and membrane fusion inhibitors FIs.
Here combined with the structure of the virus, the process of viral replication and the respective roles of drugs, I will briefly introduce you:
This is a simple flowchart of hive entering the human body and replicating
Nucleoside retrotransmime inhibitors (NRTIs): The representative of such drugs is chidovudine, which will competitively inhibit the activity of viral retrotransferase after entering the body's virus-infected cells, which will cause the virus to be unable to reverse transcription, and it is impossible to achieve the role of the virus in continuing to replicate in the body. Simply put, it terminates the pipeline of virus replication and inhibits viral synthesis.
Non-nucleoside reverse transcriptase inhibitors (NNRTIs): The representative of such drugs is nevirapine, and its role is to directly bind to the core of viral retroretroviral catalysis, directly causing the viral core to become inactive. However, the highly lethal properties alone have strong drug resistance.
Protease inhibitors (PIs): the representative is saquinavir, which acts on the second half of the virus assembly line, all the raw materials of the virus are ready, but can not be assembled, resulting in the virus hard-earned protein burned, will not achieve release and spread.
Integrase chain transfer inhibitors (INSTIs): such drugs are represented by retegvir, inhibitors have the role of intraviral integrases, the meaning of integrases is to integrate the genetic information of the virus into the enzymes in human cells, if this enzyme fails, the virus can not be integrated into human cells, it is inserted into the human DNA, inhibiting viral replication.
Membrane fusion inhibitors (FIs 5): These drugs contain a part that binds to HIV and can bind directly to the HIV virus, thus achieving the effect of blocking the virus from entering the cell.
All domestic antiviral drugs are above, and the treatment methods are also divided into different treatment plans according to age (adolescents, elderly), special groups (pregnant women, low immunity), diseases (tuberculosis, kidney disease) and so on.
So please rest assured that the current drugs to deal with HIV have been very comprehensive and perfect, as long as we take the drugs regularly in accordance with the doctor's instructions, dynamically monitor the changes in the number of CD4 and viruses to adjust the drug, victory is ahead, we do not need to be afraid.
Again, the information of all HIV patients is absolutely confidential by doctors, and whoever leaks it loses their jobs!!!! So please feel free to seek help!!
This is not only in line with the professional ethics of doctors, but also in accordance with the legal basis of the country!
<h1 class="pgc-h-arrow-right" data-track="34" > again warns those who are still on the verge of being on the verge of being caught</h1>
Of all the patients who have been consulted for VCT, most of them are caused by sexual channel infections, and having witnessed so many tragedies, Dr. Zen really wants to remind them again!
About guns, multiple sexual partners, deeply affected
People who are invaded by pornography and vulgar culture, remember to grasp the scale! Measures must be taken! Cherish yourself and love others!!
People who mix bars, nightclubs, and entertainment venues should not be carried away by money, and do not eliminate their defenses in indulgence! 、
To know that a milliliter of 100-10 million viruses in male semen, although the female vaginal secretion viral load is lower than semen, and the probability of male to male transmission is far more than that of male to female 2-3 times!!
At the same time, please do not naively think that as long as the friction process does not appear to be damaged, is it okay, and a slight point can not be?
True nature is uncontrollable, even if you control it, you must know that the HIV virus can infect epithelial cells and quickly infect T cells through the tissue barrier, this theory has been in 2018 when the Bomsel team in Paris, France, used real-time imaging technology to capture the process of HIV-infected cells!
Green is infected T cells, and red is macrophages that are instantly hit
To put it bluntly, the question of probability should never be used as a reason to escape, otherwise you will pay a heavy monetary and psychological price for it!
<h1 class="pgc-h-arrow-right" data-track="53" > summary</h1>
Accustomed to seeing the world regret in pain, we have done our best to warn everyone to clean themselves.
But nature dictates, desire is difficult to control, and how many people will fall into the hands of HIv.
So please be sure to take preventive measures and use condoms! Don't let the tragedy unfold again!!