Micro-source detection introduced ion chromatography to simultaneously determine the content of benzoic acid and sorbic acid in cosmetics

In recent years, with the continuous improvement of people's living standards, the use of cosmetics has become more and more. However, in order to achieve specific effects, manufacturers often add various additives to cosmetics, especially in cheap products, additives are very common, and excessive additives will cause damage to the skin, so the safety of cosmetics cannot be ignored.

Preservatives refer to a class of additives that can inhibit the growth of microorganisms and prevent the deterioration of substances. In order for cosmetics to last for a long time, it is necessary to prevent the multiplication of microorganisms, and the use of preservatives is one of the most economical and convenient ways. However, the accumulation of a certain concentration of preservatives on the skin will cause damage to the skin, such as damage to the stratum corneum of the skin, aggravation of cell aging, skin allergic reactions, etc. Benzoic acid and sorbic acid are added to cosmetics as preservatives to play a role in sterilization and antiseptic.

Hangzhou micro-source detection has established an ion chromatography method for the simultaneous determination of benzoic acid and sorbic acid in cosmetics, among which the detection results and retention time of benzoic acid and sorbic acid are good reproducible, the degree of separation is good and the recovery rate is high, which is suitable for daily testing.

Analytical Methods:

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Columns

Ion Pac AS11 analytical bar

Detector

Conductivity detector

Instrument model

ICS 5000+

Column temperature

30℃

Eluent

30 mmol/L NaOH eluent is elution at equal concentrations at a flow rate of 1.0 mL/min

velocity of flow

1.0 mL/min

Injection volume

25 m L

Detection results: The current method of benzoic acid and sorbic acid has a good linear relationship in the range of 1~10 mg/L, and the correlation coefficients are &gt; 0.999. The sample resale recovery rate was between 94.55% and 107.11%, and the detection limits of benzoic acid and sorbic acid were 50 ppm and 70 ppm, and the quantitative limits were 120 ppm and 150 ppm, respectively.