Romelu Lukaku and Timo Werner were both injured in Chelsea's Champions League match against Malmö, while Christian Pulisic was also sidelined; the Blues faced Norwich at Stamford Bridge on Saturday and the Carabao Cup at Southampton on Tuesday
Thomas Tutchell confirmed romelu Lukaku and Timo Werner will miss Chelsea's next two games against Norwich and Southampton due to their respective injuries.
Werner (hamstring) and Lukaku (ankle) were both forced to go off in the Champions League win over Malmö 4-0 at Stamford Bridge before half-time.
As the striker continues to recover from an ankle injury, Christian Pulisic will also be unable to play against Daniel Fark.
Tuchel said: "To make the problem a little longer, what about Pulisic? They're all out tomorrow, probably a Southampton game and then we'll see.
Werner was forced off the pitch just before half-time and suffered a hamstring injury in Chelsea's 4-0 win over Malmö
"What I can tell you for sure is that they are all in therapy, positive and not worried, but will definitely be out in the next two games.
"I don't think it makes sense to speculate [how long the players will be out] because you never know. Things may be shorter than expected or longer than expected.
"Both feel positive and not too worried."
Chelsea's manager said he did not regret letting Romelu Lukaku play Malmö while saying before the match that he thought the Belgian striker had been exaggerated during the international break.
The injured setback was a blow to Lukaku, who started his life at Stamford Bridge in good form, scoring three goals in seven Premier League games since returning to the club from Inter.
Tuchel added: "Mentally he's a bit overdone, but that doesn't mean we have to give him a break. Jorginho and Mason Mount are in the same position. That's it, they play a lot of competitions.
"That's how we feel about Romelu, so we encourage him to trust his instincts and let us think and structure the structures he can make one last contact."
Chelsea have a busy fixture schedule, with five games in 15 days, and Tuchel will need to adjust his starting line-up on Saturday, taking into account two high-profile absentees.
One suggestion is to take Kay Havertz a step further, with the German representing the striker alongside Callum Hudson-Odoi after Lukaku and Werner were replaced on Wednesday.
Tuchel said: "He's not a fake number nine because he's very strong behind the last line. When he played the number nine, we wanted him to do that, and he did it against Malmö.
"Kay didn't reach his personal highest level, so it was necessary for him to wait for some games. He did what he needed to do and he worked hard. ”
Daniel Fark's Norwich got off to a poor start to the season
Norwich headed to Stamford Bridge at the bottom of the Premier League on Saturday and have not won in the top flight so far this season, while Chelsea have won their last four games in all competitions and are at the top of the division table.
Compatriots Tuchel and Falk were former coaching colleagues at Borussia Dortmund, with Norwich coaching the Reserve team for the Bundesliga team for two seasons, while Tuchel was in charge of signal Iduna Park's first team from 2015 to 2017.
The Chelsea boss said of his opponents: "First of all I like him as a person, he is very humble.
"As far as one person is concerned, we have close communication and very good managers.
"I would love to be a player under him because he gives you a lot of confidence and trust.
"I hope we have a better ending tomorrow. We will do everything we can to win. ”