Public Network poster news reporter Wang Jue Weihai reports
Disa Pharmaceutical Group has always attached great importance to the research and development of high-tech products and the continuous improvement of product quality, the group's pharmaceutical research and development team and relevant domestic scientific research institutions to jointly tackle key problems, successfully developed by the Ministry of Health approved by the Ministry of Health to regulate blood lipids of high-tech marine biological products - DISA Haijia capsules.
Since the launch of Disha brand haijia capsules, it has been well received by the majority of customers, today we walked into the Disafimia Marine Medicine and Health Products Research Institute, interviewed Shao Xianxiang, the leader of the science and technology team of the Marine Biological Research Institute, and asked him to reveal the "past and present life" of haijia capsules for us.
Q: As a new green product of marine life, what are the specific advantages of Haijia capsules?
A: Haijia capsules use the shell of alash deepening sea snow crab as raw material, which is natural and pollution-free. Chitin extracted from the shell of snow crab, and after deacetyl to produce chitosan, the degree of deacetyl group reached 95%, industry-leading, chitosan can make immune cells in the process of differentiation increase in quantity, quality improvement, greatly improve the body's natural healing power, fundamentally regulate the function of the immune system. Disa Haijia capsule contains 270 mg of chitosan per capsule, and also contains 30 mg of VC, which synergistically balances blood lipids with each other, which is 20% higher than the lipid-lowering effect of chitosan alone, and the effect is better.
Q: Everyone is familiar with crabs, whether it is river crabs or sea crabs, they are the treasures of the plate that we like to hear, but the evolutionary history of small crabs can be traced back to the Cretaceous period more than 100 million years ago. A substance called chitosan contained in the crab shell is the secret weapon of crabs in their struggle against natural and man-made disasters. So what exactly is chitosan?
A: Chitosan is the only cationic polymeric polysaccharide in natural polysaccharides, known as the sixth element of life nutrition. Chitosan, formerly chitin, was chitin, and in 1811, a Scientist in France discovered cellulose in mushrooms, then called fungal cellulose. In 1823, a scientist in France, he separated the same object and the same kind of cellulose from the wing sheath of crustaceans or insects, and later called it chitin. Now after a lot of scientific research, we come to extract chitin, or chitosan, the main raw material is crab shell, the best quality of which is alas the deep sea snow crab, Alaska is the largest state in the United States, but because the climate is particularly cold, the entire Population of Alaska is about 1 million, and there is no industry, almost no pollution, the quality of the snow crab here is the best.
Q: What is the process of going from crab shell to chitosan, can you briefly introduce it?
Answer: Now the preparation of chitosan is generally the shell of the Alaskan snow crab crab leg, after the crab shell is decalcified and de-proteined, it gets chitin, chitin it can not be directly used by our human body, so we also have to deacetylate chitin, and then form chitosan, chitosan can be directly used by the human body.
Q: Decalcification and deproteination are easier to understand, so what is deacetyl?
A: Deacetyl is the removal of the acetyl group in chitin. The incompleteness of acetyl group detachment is related to the strength of the function of chitosan, such as its bacteriostaticity, moisturizing, adsorption, and film-forming, all of which are related to the degree of deacetyl. The traditional method of preparing chitosan is to soak chitin in a strong acid or strong alkali solution, the degree of this method of deacetyl is about 80%, and the reaction time is very long, affecting production efficiency, and our scientific research team through research, groped out a new production process, got a high deacety product, improve the production efficiency and quality of the product.
Q: What are the benefits of chitosan for our body?
A: Chitosan has many functions, it is not for a certain disease to play a treatment, but to comprehensively regulate the physiological activities of the entire body. Its unique function can be divided into several aspects: one supplement, supplementing the sixth life nutrient element required by the human body; three tones, regulating immunity, regulating PH value, regulating endocrine; three rows, excluding harmful cholesterol, excluding heavy metals, excluding toxins in the body; three drops, lowering blood lipids, lowering blood sugar, lowering blood pressure.
Q: Can the three highs be adjusted?
A: Yes. Regulation of the three high is the basic research on chitosan APIs, chitosan has a strong adsorption capacity for fat, it can adsorb fatty substances in food, thereby preventing the digestion and absorption of fat by the intestine, chitosan also has a strong adsorption capacity for cholesterol and triglycerides, and in acidic media, such as gastric acid environment, chitosan has the largest adsorption of fat. In addition, chitosan in the acidic environment of gastric juice can be exposed to its active amino group, encountered with negatively charged fat, fatty acids or bile acids will be strongly combined due to electrostatic action, thereby reducing the absorption and utilization of fat. And chitosan can be combined with bile acids to excrete the body, reabsorption into the liver bile acid will be reduced, the gallbladder empty, and the gallbladder must have a certain amount of bile acid reserves, which prompts plasma or liver cholesterol to be converted into bile acids to maintain bile acid reserves, thereby reducing the concentration of cholesterol in the blood plasma or liver.
In terms of blood sugar, chitosan is able to enhance insulin activity. An absolute or relative deficiency of insulin causes the abnormal metabolism of diabetic patients to produce excess ketone bodies, which will make the patient's body fluids acidic. It is known that for every 0.1 unit drop in pH, sensitivity to insulin decreases by 30%. The positively charged cation group formed by chitosan in the stomach can move the gastrointestinal pH slightly to the alkaline side by 0.5 units, thereby improving the sensitivity and utilization of insulin. Chitosan also has the effect of regulating the endocrine system, which can promote the recovery function of islet β-cells, and through two-way regulation, the amount of insulin secretion tends to be normal and the normal metabolism of blood sugar is maintained. Basal blood glucose is easier to control in patients with diabetes, but it is more difficult to control glycemic after meals. Persistent hyperglycemia after a meal increases the burden on islet β cells, which can impair their normal function over time. After taking chitosan, colloids form in the gastrointestinal tract, acting on insulin receptors, making them more sensitive, inhibiting the rise in blood sugar, improving urine glucose, and also reducing the stimulation of insulin secretion and the burden on β-cells.
In terms of blood pressure, the amino groups in the chitosan molecule can adsorb chloride ions to form a stable complex, promote the discharge of chloride ions, inhibit the activity of angiosconvert invertase, reduce the formation of type II angioconstricultin, increase bradykinin in vivo, and dilate blood vessels, thereby playing a hypotensive role. Chitosan can also restore the elasticity of the inner wall of blood vessels to a better state through hypolipidemic effect, which promotes a decrease in blood pressure.
Q: Can harmful substances such as heavy metals and chemical damage also be excluded?
A: Yes, there are two sources of heavy metals in our body, one is brought by the environment, such as the water we drink, the air we touch, and the other is the food we eat, heavy metals are difficult to be metabolized, so that they will be multiplied in the food chain, and finally eaten into the stomach, the human body is also difficult to excrete through natural metabolism, so that the more accumulated, the more heavy metals will bring damage to our body, especially for the liver, kidneys, brain and nerves. Chitosan adsorption of heavy metals belongs to physical adsorption, it itself does not form new organic compounds with heavy metal ions, still maintains the molecular structure of the original polysaccharides, its adsorption capacity comes from the chelating of its molecules, the use of low potential to forcibly capture water-soluble metal ions with a positive charge, after capture to form insoluble nanoparticles and precipitate, or with the urine to exclude the body.
Q: Is the chemical damage our usual pesticide residue?
A: Pesticide residues are on the one hand, as well as chemical residues such as dishwashing detergent, which will cause cancer, chronic diseases or liver and kidney damage; the other is drug damage, like many patients with three highs, long-term use of drugs that drop three highs, these drugs will produce chemical toxoids after metabolism, which will also increase the burden on the liver and kidneys.
Q: Speaking of the liver, most people know that it has a detoxifying effect, that chitosan to alleviate drug damage, but also has the function of liver protection and liver protection?
A: Yes, the liver is our main detoxification organ, one is our own physical health, such as blood lipids, fatty liver, chitosan can lower lipids, scavenging free radicals, play a positive role in liver conditioning; the other is to reduce the workload of the liver, overload work will make the liver premature aging, function reduction and damage. As just mentioned, chitosan can adsorb and eliminate heavy metals in the body, chemical damage these harmful substances, reduce the burden on the liver, and chitosan also has a good adsorption effect on alcohol, for example, before drinking alcohol and socializing, taking chitosan substances can form a protective film in the stomach, this protective film can wrap the alcohol, so that our body does not absorb, directly excreted, which also reduces the burden of liver metabolism.
Brief introduction:
The enterprise behind the Disafimia brand - DisshaFimia Health Industry Co., Ltd., with a registered capital of 50 million yuan, is headquartered in Weihai, Shandong, a livable city in the world, and is a comprehensive industrial group integrating the research and development, production, sales and entrepreneurship incubation of marine biological health products.
Disa Pharmaceutical Group, the introduction of Weihai City's first batch of marine pharmaceutical high-end talents, under the establishment of 12 research institutes, with full-time R & D personnel of more than 300 people, including 15 doctors, equipped with more than a thousand sets of leading scientific research instruments and equipment at home and abroad. Among them, the Disafimia Marine Biological Research Institute is mainly researched by marine medicines, functional foods and other marine biological products, and provides technology development and technical services in related fields. It aims to base itself on Weihai and make use of the advantages of Weihai's thousand-mile coast to carry out integrated innovation, digestion, absorption and re-innovation and original innovation in specific technical fields of marine biological products and functional food technologies, and build a public research and development platform for Shandong Province and even the whole country.