Men eat grapefruit for 7 days in a row after "muscle dissolution"! This is a mistake you may be making

Recently, it is the season when grapefruit is on the market in large numbers

I think many people will always eat a bite after a meal

But would you think?

Can eat grapefruit also produce muscle dissolution?

Eating grapefruit to eat "muscle dissolving"

What's going on?

Mr. Liu, 58, of Wuhan, loves to eat grapefruit,

So every day after work, he would carry a grapefruit home.

And one person can eat a whole thing.

Not long ago, Mr. Liu suddenly had sore limbs,

Weakness in the hands and feet, followed by worsening of symptoms.

The family found that he could not even walk,

Rush him to the hospital.

The doctor obtained Mr. Liu's blood test results and found that creatine kinase was more than 5 times higher than the normal value. This is muscle dissolution caused by acute injury!

What is muscle dissolution?

Rhabdomyolysis syndrome refers to the destruction and disintegration of the rhabdomyotic muscle due to various reasons such as squeezing, exercise, high fever, drugs, inflammation, etc., so that the body's creatine kinase, myoglobin and other muscle cell components enter the extracellular fluid and blood circulation, causing disturbances in the human internal environment.

Symptoms include "soy sauce urine" (darker urine color), weakness, fever, etc., which can seriously induce heart failure, and patients have chest tightness and wheezing, which can cause death if not treated in time.

Physical causes of the disease include excessive exercise, electric shock, extreme body temperature (high or low temperature), and muscle crush injuries. Non-physical causes include metabolic disorders such as hypothyroidism, hypokalemia, diabetic ketoacidosis, infections, autoimmune diseases, poisons, and endocrine and genetic factors.

Previously, after diving athlete Wu Minxia's husband Zhang Xiaocheng ate 3 kilograms of crayfish alone, the next day his body experienced fatigue and fever symptoms, and his condition worsened after going to the gym for fitness, and his urine also became soy sauce color. The hospital examination found that creatine kinase soared, reaching 5613, and the normal value of the average ordinary person was 176 (upper limit), suffering from the disease of "rhabdomyolysis", and the result was directly admitted to the intensive care unit (ICU).

But Mr. Liu has not had high-intensity exercise recently, nor has he been injured unexpectedly, how can he be "muscle dissolved"?

Repeated questioning learned that 3 months ago, Mr. Liu was diagnosed with hyperlipidemia, and he took atorvastatin for lipid-lowering treatment under the advice of the doctor, and before the symptoms appeared, he had eaten grapefruit for a week.

"Statins

Cannot be eaten with grapefruit. ”

Doctors told him that the most obvious side effect of statins was the cause of rhabdomyolysis.

Yuzu contains furan coumarin compounds, which are inhibitors of the main drug decomposition enzymes in the human body, which rapidly increase the concentration of statins in the blood in a short period of time, resulting in a doubling of the amount of drugs entering the blood, and inhibiting the decomposition and metabolism of drugs in the body, greatly increasing the accumulation of drugs and toxic side effects.

As long as you stop statin lipid-lowering drugs and don't eat grapefruit in the near future, muscle soreness will soon be relieved and walking can return to normal.

"The public does not have to panic too much, and it is relatively rare for grapefruit to be poisoned with medicine."

Doctors remind: Compared with ordinary grapefruit, grapefruit is also commonly known as grapefruit is more harmful, and it is best to avoid eating it during taking medicine. In addition, all citrus fruits and their juices such as citrus, oranges, etc. should also be noted.

These "common medicines"

Nor can it be eaten with grapefruit

So in addition to some statins, what other drugs can not be taken with citrus fruits such as grapefruit, grapefruit, and ceviche, and their juices such as grapefruit juice and grapefruit juice?

The following most common drugs must also be paid attention to:

01 Antihypertensive drugs (such as nifedipine)

In addition to yuzu containing furan coumarin, which can inhibit the metabolism of antihypertensive drugs and increase their blood concentration, yuzu also contains potassium, which is a natural antihypertensive drug.

If you take antihypertensive drugs while eating grapefruit, it is like overdosing the drug, causing a sudden drop in blood pressure, light dizziness, nausea, palpitation, and heavy cases of occasional angina, myocardial infarction or stroke.

02 Anxiolytic or sedatives

Some anxiolytic drugs such as diazepam and midazolam cannot be taken with grapefruit, because grapefruit will prolong the action time of such sedative hypnotics, causing dizziness and drowsiness.

03 Antiallergic drugs (eg, cismin, terfenadine)

For example, cistimil, terfenadine, etc. can not be taken with grapefruit, because the consumption of grapefruit after taking such drugs will aggravate the adverse reactions of anti-allergic drugs to the heart, liver and gastrointestinal tract.

04 Anti-rejection drugs (such as cyclosporine)

For example, cyclosporine cannot be taken with grapefruit, because the blood concentration increases, adverse reactions increase, and increase liver and kidney toxicity. If such drugs are eaten with grapefruit for a long time, there is a risk of tumor induction.

Transferred from Healthy Sichuan

Source: Sichuan News Network