This prescription is the famous prescription of "Treatise on Typhoid Fever" for the treatment of palpitations and pulse knots. The evidence is caused by the lack of yin blood and the lack of yang energy. Yin blood is insufficient, the blood veins cannot be filled, coupled with the lack of yang qi, the inability to agitate the blood veins, the pulse qi is not connected, so the pulse is formed; the yin blood is insufficient, the heart and body are not nourished, or the heart and yang are weak, can not warm the heart and veins, so the heart palpitates. It is advisable to nourish the heart yin, nourish the heart and blood, benefit the heart qi, warm the heart and yang, and restore the pulse and fix palpitations. In the formula, the licorice is warm and invigorating, passes through the meridians, benefits the blood and qi, and nourishes the heart in a slow and urgent manner. The two medicines are reused, nourishing qi and nourishing blood to restore the pulse, and they are all the king's medicines. Ginseng and jujube nourish the heart and spleen, and the combination of licorice and licorice is beneficial to the heart and qi, and the spleen is nourished by the source of qi and blood metaplasia; Ejiao, Mai Dong and Ma Ren nourish the yin and nourish the blood and nourish the heart, and the rehmannia nourishes the heart and yin, nourishes the heart and blood, and fills the blood and veins, which are all subordinate medicines. Cinnamon branches and ginger warm the heart and yang and pass the blood veins, so that the qi and blood are unblocked, the pulse and qi are connected, and the thick flavors are nourishing but not greasy, and they are all adjuvants.
The combination of cinnamon and licorice can also be sweet and yang, and the heart and blood can be combined to revitalize the heart and yang. In usage, add sake decoction to warm the yang and pass the veins, to help the medicinal power, and to make medicine. The combination of various medicines nourishes but not greasy, warm but not dry, so that the qi and blood are abundant, the yin and yang are harmonized, and the function of nourishing qi and nourishing the blood, nourishing yin and restoring the pulse. Because boiled licorice and ginseng can also replenish lung qi, moisten the lungs and relieve cough; Ejiao and Mai Dong are good at nourishing lung yin and moistening lung dryness; rehmannia and hemp seeds are long in nourishing kidney water, and are used in combination with Ejiao and Mai Dong, which have the function of "gold and water grow together", so they can be used for the treatment of patients with qi and yin injuries caused by fatigue and pulmonary impotence. However, for those who suffer from yin injury and lung dryness, the amount of ginger, cinnamon and wine in the recipe should be reduced or not used, because after all, warm medicine has the disadvantage of depleting yin fluid, so it should be used with caution.
1. Key points of use: Boiled licorice soup is a tonic for yin and yang, qi and blood. The clinical application is based on palpitations, pulse generation, virtual win and less qi, and tongue light and less lichen as the key points of syndrome differentiation.
2. Arrhythmia: A meta-analysis of the literature on the treatment of patients with arrhythmia with the addition or subtraction of licorice decoction was conducted, and the quality of the included literature was evaluated by using the Jadad scoring scale, and the clinical efficacy was meta-analyzed. Results: Eight randomized controlled clinical trials were included. The overall efficacy of licorice decoction in the treatment of arrhythmia, coronary heart disease combined with arrhythmia, bradyarrhythmia, premature ventricular contraction and palpitation was better than that of the Western medicine group, and the adverse reactions of Western medicine were reduced. (Inner Mongolia Traditional Chinese Medicine)
3. Premature contractions: 100 cases of premature ventricular contractions were treated with the addition or subtraction of this prescription, and 78 cases were compared with the treatment of mexiletine hydrochloride, and the course of treatment was 2 months. The clinical efficacy evaluation was based on the disappearance of premature beats monitored by Holter electrocardiogram after treatment, and the return of electrocardiogram to normal after treatment, and the reduction of the number of premature beats monitored by Holter monitoring by more than 50% was improved. Results: The total effective rate was 96% in the treatment group and 89% in the control group, and the reduction of the number of early Holter recording chambers in the treatment group was better than that in the control group. (Anhui Medicine)
4. Insomnia: 30 cases of refractory insomnia in the elderly were treated with the addition or subtraction of licorice decoction, and 30 cases were compared with the alprazolam treatment group, and the course of treatment was 21 days. The clinical efficacy evaluation was based on the recovery of normal sleep, more than 6 hours of sleep per night, deep sleep, and less dreams and no fatigue. Results: The total effective rate was 93.33% in the treatment group and 86.67% in the control group. The control group had drug dependence, and the treatment group did not have drug dependence. (Chinese Journal of Geriatrics, Issue 17, 2012)
5. Heart failure: 25 patients with heart failure with dilated cardiomyopathy were treated with licorice decoction combined with Western medicine, and 24 patients were treated with Western medicine (diuretics, vasodilators, digitalis and angiotensin-converting enzyme inhibitors, etc.), and the course of treatment was 3 weeks. The clinical efficacy evaluation was based on the basic disappearance of symptoms and signs, and the improvement of cardiac function by more than 2 grades. The changes of cardiac function indexes such as left ventricular end-diastolic volume, left ventricular end-systolic volume and left ventricular ejection fraction were observed by ultrasound. Results: In the treatment group, 17 cases were effective, 6 cases were effective, and 2 cases were ineffective, with a total effective rate of 92%. In the control group, there were 11 cases with significant response, 8 cases with efficacy and 5 cases with an ineffective rate, with a total effective rate of 79.2%. (Journal of Liaoning University of Traditional Chinese Medicine)
6. Constipation: 42 cases of habitual constipation were treated with licorice decoction and flavor, and the course of treatment was 10 days. Results: Thirty-eight patients had normal bowel movements after 5 days of treatment, and 4 patients had normal bowel movements after 10 days of treatment. (Shandong Journal of Traditional Chinese Medicine, Issue 1, 2007)
7. Myocarditis: 45 cases of viral myocarditis were treated with addition or subtraction of this prescription, and 25 cases were treated with Western medicine (ATP, coenzyme A, cytochrome c, vitamin C), and the course of treatment was 4~6 weeks. The clinical efficacy evaluation was based on the disappearance of symptoms and signs, and the normal ECG, cardiac enzymes and cardiac function tests. Results: In the treatment group, 16 cases were cured, 6 cases were effective and 2 cases were ineffective, and the total effective rate was 95.5%. In the control group, 5 cases were cured, 8 cases were effective, 7 cases were effective, and 5 cases were ineffective, with a total effective rate of 80%. (Yunnan Journal of Traditional Chinese Medicine)
8. Precautions for use: use water and wine to decoction, simmer for a long time, and use with caution if yin deficiency and internal heat.