Photosensitive proteins are important tools for optogenetic research, and new photosensitive proteins are highly enthusiastic
Photosensitive proteins, also known as photosensitive proteins, are a class of proteins that can respond to a specific wavelength of light. In living organisms, light-sensitive proteins are able to sense the presence of light and convert it into intracellular signals, thereby regulating the organism's ability to perceive light. In the biological world, photosensitive proteins have a wide range of sources and are widely found in bacteria, cyanobacteria, green algae, fungi, animals, plants and other biological tissues.
There are various types of photosensitizing proteins, including rhodopsin channel protein 2 (ChR2), halophilic violet (NpHR), archaeal rhodopsin (ArchT), cryptochrome protein, plant phototropin, opsin, etc. According to different functions, photosensitive proteins can be divided into two categories: excitatory photosensitive proteins and inhibitory photosensitive proteins, and according to different modes of action, photosensitive proteins can be divided into monomeric systems, heterodimer systems, and oligomeric systems. In recent years, thanks to the progress of molecular engineering and engineering transformation technology, photosensitive proteins have been widely studied and applied.
Opsin is the main component of photoreceptors, which can be divided into two categories: opsin in the visual system and opsin in the non-visual system. Opsins are often related to the ability to detect light, and have certain development prospects in the fields of visual imaging, circadian clock regulation, skin cancer/melanoma cancer treatment, etc.
According to the "2024-2028 China Photosensitive Protein Industry Market Supply and Demand Status and Development Trend Forecast Report" released by the Xinsijie Industry Research Center, purple red pigment channel protein 2 (ChR2) is a common excitatory photosensitive protein that can be activated by 473nm blue light irradiation, triggering cation influx, resulting in depolarization of the cell membrane, thereby stimulating the activation of neurons. Violetin channel protein 2 is also a photoactivated cation channel that mainly allows the passage of sodium and potassium ions.
Optogenetics is a new light-controlled cell technology, the basic principle of which is to introduce light-sensitive proteins into target cells through genetic engineering technology. Optogenetics has broad applications in the treatment of neurological diseases, retinal diseases, and heart diseases. Retinal diseases are currently the main research scenario of optogenetics, and the global research companies include Bionic Sight (USA), Nanoscope Therapeutics (USA), GenSight Biologics (France), Allergan (Ireland), etc. As an important tool for optogenetics research, with the development and application expansion of optogenetics technology, the market space for photosensitive proteins will be further expanded.
Industry analysts said that photosensitive proteins come from a wide range of sources, but the mainstream photosensitive proteins are all from non-human species, and there are potential problems such as cytotoxicity and immune response after being introduced into the human body, and the existing photosensitive protein systems mostly rely on blue light, with poor penetration and limited therapeutic effect, so the market has a strong demand for high-efficiency, high-sensitivity, low-toxicity and new photosensitive proteins. At present, new photosensitive proteins under development in China include PsCatCh2.0, YGS24, VR1.0, etc.
2024-2028 China photosensitive protein industry market supply and demand status and development trend forecast report
Report source: New Thinking World
Chapter 3 Analysis of the characteristics of the photosensitive protein industry in 2023
Section 1 Analysis of market concentration in the photosensitive protein industry
Section 2 Analysis of Porter's Five Forces Model in the Photosensitive Protein Industry
First, the bargaining power of suppliers
2. The bargaining power of the purchaser
3. The threat of new entrants
Fourth, the threat of substitutes
5. Competition between enterprises
Chapter 4 Global Market Analysis of Photosensitive Protein Industry
Section 1 Overview of the global photosensitive protein industry market in 2023
Section 2 Global Photosensitive Protein Industry Market Overview in Major Countries in 2023
1. Europe
2. North America
3. Asia
Section 3 Forecast of the market trend of the global photosensitive protein industry in the next five years
Section 4 Analysis and forecast of the economic environment of the photosensitive protein industry in 2024
1. Trends in the development of the world economy and its impact forecast
2. Monetary and exchange rate policy development trends and impact forecasts
3. The development trend and impact prediction of residents' consumption level
Section 5 Analysis of Global Production Trends
1. Global production statistics
2. Forecast of global output development trends
Section 6 Analysis of Key Vendors
Chapter 5 The overall development of China's photosensitive protein industry
Section 1 Analysis of the scale of China's photosensitive protein industry
1. Analysis of the scale of industrial units
2. Analysis of the scale of industrial personnel
3. Analysis of the scale of industrial assets
Fourth, the analysis of the scale of the industrial market
Section 2: Market Barriers
Section 3: Analysis of the Competition Situation
1. Competition among existing enterprises
2. Analysis of potential entrants
III. Substitute Substitute Weiwei Analysis
Section 4 Comparison of International Competitiveness
Section 5 Analysis of Market Concentration
Chapter 6 Analysis of the production status of photosensitive proteins in China
Section 1 The overall scale of the photosensitive protein industry
Section 2 Overview of the production capacity of photosensitive proteins
1. Production capacity analysis from 2021 to 2023
2. Production capacity forecast for 2024-2028
Section 3 Overview of the market capacity of photosensitive proteins
1. Market capacity analysis from 2021 to 2023
2. Investigation of capacity allocation and capacity utilization
3. Market capacity forecast for 2024-2028
Section 4 Life Cycle Analysis of the Photosensitive Protein Industry
Section 5 Supply and demand of photosensitive protein industry
Section 6 Analysis of import and export of China's photosensitive protein industry
1. Analysis of imports of photosensitive protein industry
2. Export analysis of photosensitive protein industry
3. Statistics of import and export data of photosensitive protein industry
Fourth, the outlook for the import and export of photosensitive proteins
Chapter VII Analysis of Raw Material Supply
Section 1 Main Raw Materials
Section 2 Historical Prices and Supply of Major Raw Materials
Section 3 Current Prices and Supply of Major Raw Materials
Section 4 Forecast of future prices and supply of major raw materials
Chapter 8 Analysis of the Downstream Market Demand of the Photosensitive Protein Industry
Section 1 Analysis of the user's demand for a pair of photosensitive proteins
1. Analysis of the development status of the user
2. Application analysis of photosensitive proteins in user 1
3. The scale and trend of the user's demand for photosensitive proteins
Section 2 Analysis of user demand for photosensitive proteins
1. Analysis of the development status of user 2
2. Application analysis of photosensitive proteins in user 2
3. The scale and trend of user demand for photosensitive proteins
Section 3 Analysis of the user's demand for three pairs of photosensitive proteins
1. Analysis of the development status of user three
2. Application analysis of photosensitive proteins in user 3
3. The scale and trend of user demand for photosensitive proteins
Chapter 9 Production Process and Technological Progress of Photosensitive Proteins at Home and Abroad
Section 1 Introduction to the main production processes at home and abroad
Section 2 Overview of core production processes at home and abroad
Section 3 Research Progress on Production Technology at Home and Abroad
Section 4 Technology Development Trend of Photosensitive Protein Industry....