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Case Profile
A grandmother in her 80s came to the clinic with new blisters on her face and scalp. The patient complains of long-term recurrent blisters on the face with tight blister walls. She denies any history of mucosal involvement. At the time of presentation, the patient was taking the antihypertensive drugs candesartan and hydrochlorothiazide.
Specialist examination: multiple erythema on the face, with serous, partially erosive, tight-walled blisters at the base of the erythema, and scarring at some blisters (Fig. 1).
Figure 1: Erythema on the face with serous, partially erosive, tight-walled blisters at the base of the erythema. (Cited in References)
Histological examination is shown in Figure 2.
Figure 2: Histology of the skin surrounding the left mandibular lesion shows superficial and perivascular dermatitis, lymphocytic and eosinophilic infiltration, and subcutaneous fissure formation (hematoxylin-eosin staining, original magnification x100). (Cited in References)
Q:
What is the most likely diagnosis?
A:
A. Acquired epidermolysis bullosa
B. dermatitis herpetiformis
C. Cicatricial pemphigoid
D. Porphyria cutanea tarda
Answers in this issue
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参考文献:[1]Sorger C,Mentzel J,Simon JC,Treudler R.Blistering and scarring confined to the head. J Dtsch Dermatol Ges.2020 Jun; 18(6):641-643.doi:10.1111/ddg.14103.Epub 2020 May 24.PMID:32447833.
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