Acid suppression, anti-reflux, heartburn, treatment of reflux esophagitis, introduction of 3 kinds of Western medicines, 3 kinds of proprietary Chinese medicines:
Omeprazole is a commonly used acid suppressant in clinical practice, which belongs to the proton pump inhibitor and is a fat-soluble weak alkaline drug. Easy to concentrate in the acidic environment, specifically act on the site of the gastric wall cell proton pump (H+, K+-ATPase), and converted to the active form of sulfinamide, through the disulfide bond and the thiol group of the proton pump irreversible binding, thereby inhibiting the activity of H+, K+-ATPase, blocking the final step of gastric acid secretion, so that H+ in the parietal cells can not be transported to the gastric cavity, so that the acid content in the gastric juice is greatly reduced. It has a strong inhibitory effect on basal gastric acid and gastric acid secretion caused by stimulation. After medication, with the obvious decrease in gastric acid secretion, the pH in the stomach increases rapidly. Relieves heartburn and pain faster. Cure rates for duodenal ulcers are also higher and recurrence rates are lower.
Clinically, omeprazole is mainly used for duodenal ulcer and Dro-Ai syndrome, but can also be used for gastric ulcers and reflux esophagitis, with amoxicillin and clarithromycin or in combination with metronidazole and clarithromycin to eradicate Helicobacter pylori. Omeprazole is the drug of choice for the treatment of gastroesophageal reflux disease, and its acid inhibition effect is powerful and long-lasting, which can quickly and persistently control reflux and heartburn symptoms.
Ranitidine is a selective H2 receptor antagonist, which can competitively antagonize histamine to bind to H2 receptors on gastric wall cells, effectively inhibit the secretion of basal gastric acid and gastric acid secretion caused by histamine, pentapeptide gastrin and food stimulation, reduce pepsin activity, and inhibit the secretion of pepsin, but have no effect on the secretion of gastrin and sex hormones. The acid inhibiting effect of ranitidine is 5-12 times that of cimetidine, which has the characteristics of rapid action and long-acting, and the inhibitory effect on liver drug enzymes is lighter than that of cimetidine, and there is less interaction,
Clinically, ranitidine is suitable for active duodenal ulcer, preventing recurrence of duodenal ulcer, gastric ulcer, reflux esophagitis, Dro-Ai syndrome, relieving stomach pain, heartburn, and acid reflux caused by excessive stomach acid. Ranitidine can inhibit basal gastric acid secretion, which has a poor effect on gastric acid secretion caused by eating, and is mainly used in patients with mild and moderate gastroesophageal reflux disease.
Aluminum magnesium carbonate is a commonly used antacid drug in clinical practice, which belongs to the aluminum magnesium mixture, which can neutralize gastric acid, maintain gastric juice PH between 3-5, neutralize 99% of gastric acid, inactivate 80% of pepsin, and the antacid effect is rapid, mild and long-lasting. In addition, aluminum magnesium carbonate can also increase the synthesis of prostaglandin E2, enhance the gastric mucosal barrier effect, promote the release of epidermal growth factors in the gastric mucosa, increase the content of phospholipids in the hydrophobic layer of the lower mucus mucus, and prevent gastric mucosal damage caused by acid reverse osmosis. Aluminum magnesium carbonate can also adsorb and bind pepsin, directly inhibit its activity, favoring the repair of the ulcer surface, but also combined with bile acids and adsorption of hemolytic phosphatidylcholine, to prevent these substances from damaging and destroying the gastric mucosa.
Clinically, magnesium aluminum carbonate is suitable for acute and chronic gastritis, duodenoccalitis, gastric ulcer, duodenal ulcer, can alleviate the symptoms of heartburn, acid reflux, nausea, vomiting, bloating and other symptoms caused by excessive stomach acid, and can also be used for reflux esophagitis, bile reflux and prevention of gastric mucosal damage caused by nonsteroidal anti-inflammatory drugs. The antacid action of magnesium aluminum carbonate is transient, mild or intermittent in patients with reflux esophagitis can be used for temporary relief of symptoms.
The zuo jin pill group is Huang Lian and Wu Zhu Yu, and the two drugs are combined to play the functions of diarrhea, liver thinning, stomach and pain relief.
Modern pharmacological studies have confirmed that Zuojin Pill has the effect of inhibiting gastric acid secretion, which can inhibit gastric secretion, reduce the amount of gastric juice and total acid excretion, and can also reverse antagonistic gastrin to stimulate gastric acid secretion.
Clinically, Zuo Jin Pill can be used for stomach pain, full flank ribs, irritability and anxiety, acid swallowing, noisiness in the stomach, vomiting acid, bitter mouth, dislike of hot drinks, red lichen of the tongue, pulse strings or numbers caused by the stomach of the liver fire offender; Gastroesophageal reflux disease is seen in the above symptoms.
The composition of Shu Liver And Stomach Pills is Xiangfu (vinegar), Chai Hu (vinegar), Citrus Shell, Magnolia (ginger), Betel Nut, Tangerine Peel, Green Peel (Vinegar Stir-fry), Morning Glory (Stir-fried, Cardamom, Chicken Inner Gold (Stir-fried), Sandalwood, Citron, White Peony (Bran Stir-fry), Yan Hu Suo (Vinegar Stir-fry), Five Spirit Fat (Vinegar System), and all kinds of medicines are combined to play the effect of soothing liver depression, stagnation and neutralization.
Modern pharmacological studies have confirmed that Shu He Jian Gastric Pills have the effect of regulating gastrointestinal hormones, can reduce serum vasoactive intestinal peptides, increase plasma motilin and serum gastrin content, and improve the symptoms of reflux esophagitis.
Clinically, Shu He Jian Stomach Pills can be used for acid swallowing caused by hepatic and gastric disharmony, and symptoms include noisy acid swallowing, burning or burning pain in the spleen, hiccups, and pulse strings; Reflux esophagitis and peptic ulcer are seen in the above symptoms.
The four-square stomach tablets are sea mantis, Zhejiang shellfish, evodia (salt water system), Sichuan neem (peeled wine stir-frying), Yan Hu Suo (vinegar), Huang Lian, bitter almonds, persimmon cream, agarwood, all kinds of medicines are combined, playing a role in toning the liver and stomach, acid and pain relief.
Modern pharmacological studies have confirmed that Sifang gastric tablets have the effect of inhibiting gastric acid secretion, can reduce the amount of gastric juice secretion, reduce the total acid and pepsin excretion of gastric juice.
Clinically, four-square stomach tablets can be used for hepatic and gastric disharmony, gastric loss and descent caused by stomach pain or fullness, bitter mouth, reduced intake, fecal irregularities, and red tongue veins; Reflux esophagitis is seen in the above symptoms. #谣零零计划 #
