Description: Hello, doctor. The baby is currently 4 years and 5 months old. The physical examination showed that he was short in height. In the past year, his height has increased by 4.5cm, and his bone age lags by a year and a half to more than two years. He also underwent a growth hormone test. Excuse me:
1. Checklist, what does it mean that the IGFBP insulin-like growth factor binding protein-3 ratio is low? Can you explain growth hormone deficiency?
A: This ratio is the ratio of the first two items, and the values of the first two items are within the normal range. The proportion problem is not too large, and can only be combined with clinical symptoms. And this value is only a reference, and does not explain the lack of growth hormone.
2. What is the difference between allergic growth hormone (after exercise) and general growth hormone?
Answer: In general, the secretion of growth hormone is pulse-like, that is, the growth hormone values measured at different times on the same day are not the same, so generally qualified hospitals will measure the values after exercise. This is more accurate, but the reference value of each hospital is different, and there will be errors. In general, this is the case
3. What do you think might be the reason you're short? When is growth hormone therapy needed?
A: The baby's bone age does not match the actual age. In the diseased state, bone age often does not match actual age. Bone age less than actual age may be related to stunted growth, growth hormone deficiency, hypothyroidism, etc.
What is growth hormone?
Growth hormone is a hormone produced by the pituitary gland and is indispensable for human growth.
Recombinant human growth hormone, the same as human growth hormone produced by the human body, is produced using genetically engineered recombinant technology, which has the same effect as human growth hormone, such as promoting the growth of bones, internal organs and the whole body, promoting protein synthesis, regulating fats and minerals Here "growth hormone" refers to "recombinant human growth hormone".
The appropriate age for growth hormone injections is under 16 years of age. Growth hormone is an endocrine hormone in the body that promotes the growth and development of the body. However, after the injection of growth hormone, a series of side effects, such as hyperglycemia, need to be prolonged or discontinued before it can return to normal. Some patients are prone to symptoms such as edema, joint pain, and muscle soreness at the injection site after injection.
If you have more questions about your child's "short stature", please comment below.