Among our compatriots, the incidence of a variety of chronic diseases is rising, and there is a wide range of self-medication habits, and many families have small medicine boxes, and it is a common phenomenon to take medicines in a hurry. Some people, even develop the habit of taking medicine first and then looking for a doctor, do not carefully read the instructions before taking medicine. Taking medicine in this way, the discomfort of the body has not subsided, but new problems have followed, and drug-induced cardiovascular disease is one of the typical.
Drug-induced cardiovascular disease is caused by drugs, including drug-induced arrhythmias, drug-induced heart failure, drug-induced angina, drug-induced hypertension, and drug-induced hypotension. Today we focus on analyzing the effects of drugs on blood pressure. Drug-induced hypertension is the effect of adverse drug reactions or combination drugs, as well as hypertension caused by improper medication. Drug-induced hypertension, can cause headache, dizziness, palpitations, insomnia, fatigue and other symptoms, if you measure blood pressure at this time, you will find that blood pressure rises, beyond the normal range, or causes blood pressure levels to fluctuate, blood pressure increases significantly, and even edema. There is a temporal relationship between blood pressure and symptoms and taking medications. After stopping taking the drug, the symptoms disappear and the blood pressure returns to the previous level. A drug agonist test was performed and blood pressure rose again. The latter two features are important indicators for the diagnosis of drug-induced hypertension.
Drugs that cause drug-induced hypertension, common in a total of 7 categories. The first category is drugs that cause water and sodium retention, such as glucocorticoids, estrogens, etc., and long-term use of oral contraceptives is also a common cause of drug-induced hypertension. The second category is vasoconstrictor drugs, such as posterior pituitary loin and ergometrine. Category 3 is central stimulants, such as caffeine and methyl matemate. Category 4 is sympathetic stimulants, such as thyroid hormones, sibutramine, and ephedrine. Category 5 is vasodilators, such as nitroprusside. Category 6 is immunosuppressants, for example, cyclosporine. Category 7 is opioid receptor antagonists, such as naloxone.
It is worth noting that long-term use of drugs that can cause drug-induced hypertension, if there is a lack of relevant awareness, neglect of blood pressure management, may cause complications such as cerebrovascular disease or renal insufficiency. In addition, ordinary people should always keep in mind that it is a three-point poison of medicine. The drugs we usually have at home may also cause drug-induced hypertension. For example, ibuprofen for antipyretic and analgesic, proprietary Chinese medicine containing licorice.
Drugs cause fluctuations in blood pressure, which not only causes an increase in blood pressure, but also leads to drug-induced hypotension, dizziness, fatigue, drowsiness, lack of energy, palpitation, chest tightness, numbness in the extremities, syncope, blood pressure, systolic blood pressure less than 90mmHg, diastolic blood pressure below 60mmHg. Or blood pressure, although still within the normal range, but the blood pressure drops too quickly or by a large margin. It should be noted that this condition may lead to hypoperfusion, causing cerebral ischemia.
Drug-induced hypotension, usually caused by 5 classes of drugs. The first category is drugs with antihypertensive effects, such as diuretics and nitrates. The second category is drugs for the treatment of arrhythmias, such as quinidine and lidocaine. The third category, is anti-inflammatory drugs, when used in excess, through a large amount of sweating or allergy mechanisms, leading to hypotension and even shock. Category 4 is drugs that cause allergies, such as antibiotics, antifungals, blood products, or biological products. The fifth category is sedative sleeping pills, such as phenytoin and diazepam.
Drug-induced cardiovascular diseases have individual differences. For example, elderly, female, obese, with a family history of cardiovascular disease, diabetics, kidney disease, etc., the risk of drug-induced cardiovascular disease is higher, these people, when taking drugs, should seriously accept professional guidance, should not take their own medication. In addition, it should also be noted that patients with cardiovascular disease, if the medication is improper, when there is a drug-induced blood pressure fluctuation or other problems, the symptoms will be more serious, for example, leading to a hypertensive crisis, systolic blood pressure exceeding 180 mmHg, diastolic blood pressure more than 120 mmHg, causing hypertensive encephalopathy, heart failure, blurred vision, fundus bleeding, need to be rescued in time.
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