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Many people have been revoked from the title of deputy chief physician! The latest report of the Ministry of Science and Technology

Many others were revoked their Doctorates.

Lead

The new year has just begun, and the results of the investigation and handling of another batch of medical research integrity cases have been announced. From the perspective of regional distribution, the number of cases in Shandong Province announced this time is still the largest, accounting for 25 of the 46 cases. Many people have been dismissed from the posts of deputy chief physician and associate professor, disqualified from promotion, revoked doctoral degree, and removed from the post of head of department.

According to statistics from the "medical community", in 2021, the Ministry of Science and Technology, the Health Commission and other departments issued a total of 17 batches of normalized circulars, involving 405 cases of academic fraud and misconduct, most of which were self-examination and self-correction of medical institutions and notifications. Among them, Shandong Province has the largest number of medical institutions involved, reaching 48. In the 119 cases of paper fraud as of December 1, 2021, 20 of the 293 people involved were revoked their titles, and 156 people were disqualified from promotion and titles for a certain number of years.

The "medical community" believes that judging from the number of cases and the intensity of punishment in this batch of announced cases, in the new year, the intensity of medical research integrity investigation and punishment will be even greater. It is hoped that the "Guiding Opinions on Deepening the Reform of the Title System of Health Professionals and Technicians" issued in August 2021 will be rolled out as soon as possible, breaking the "only paper" tendency in the evaluation of professional titles, and solving the problem of medical research fraud from the root.

On January 27, the website of the Ministry of Science and Technology announced the results of the investigation and handling of 46 cases of medical research integrity in education and medical institutions:

I. The paper "Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191" by Liu Huawei of Qingdao University Affiliated Hospital and huang Deyu as the first author. After investigation, the paper was found to be fraudulent. Liu Hua and Huang Deyu are dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as nominators or recommenders, nominated or recommended persons, evaluation experts, etc., recorded in the archives of scientific research creditworthiness untrustworthiness, give scientific research integrity admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

Second, The paper "Syndecan-1 suppresses cell growth and migration via blocking JAK1/STAT3 and Ras/Raf/MEK/ERK pathways in human colorectal carcinoma cells" by Mao Yongjun of the Affiliated Hospital of Qingdao University is the corresponding author and Wang Shaojun is the first author. After investigation, the paper was falsified and improperly signed. Mao Yongjun was unaware of the signature of the paper. Wang Shaojun was dealt with as follows: 1 year of demerit punishment, cancellation of application for or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, and qualifications for scientific and technological talents for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, and appraisal expert for 5 years, recorded in the archives of scientific research creditworthiness untrustworthiness, given scientific research creditworthiness admonitions and talks, canceled participation in this year's appraisal and appraisal, and the annual assessment must not be determined as qualified or above.

The paper "Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells" by Wang Shilei of Qingdao University Affiliated Hospital and First Author Du Qing. After investigation, the paper was found to be fraudulent. Du Qing (merged with another paper) and Wang Shilei (merged with another paper) were dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 6 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc. for 6 years, recorded in the scientific research integrity untrustworthy file, give scientific research integrity admonition talks, cancel participation in this year's appraisal and evaluation, and the annual assessment must not be determined as qualified or above.

The paper "Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation." BMI1”。 After investigation, the paper was found to be fraudulent. Liu Pei was dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc. for 5 years, recorded in the scientific research integrity untrustworthy file, given scientific research integrity admonition talks, canceled participation in this year's appraisal and appraisal, and the annual assessment must not be determined as qualified or above; Jiang Xiangjun was dealt with as follows: Warning punishment for 6 months, cancellation of application for scientific research projects, Academic awards, honorary titles and other qualifications for 1 year, the annual assessment shall not be determined as excellent grades.

The paper "MicroRNA-146-5p promotes proliferation, migration and invasion in lung cancer cells by targeting claudin-12" by Liu Yuanwei of the Affiliated Hospital of Qingdao University and first author by Sun Xianghong. After investigation, the paper was falsified and improperly signed. Liu Yuanwei and Sun Xianghong were dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as nominators or recommenders, nominated or recommended persons, evaluation experts, etc. for 5 years, recorded in the archives of scientific research creditworthiness untrustworthiness, give scientific research creditworthiness admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Long non-coding RNA PICART1 suppresses proliferation and promotes apoptosis in lung cancer cells by inhibiting JAK2/STAT3 signaling" by Gao Yufang of the Affiliated Hospital of Qingdao University and Zhao Jingming as the first author. After investigation, the paper was falsified and improperly signed. Gao Yufang was unaware of the signature of the paper. Zhao Jingming was dealt with as follows: 1 year of demerit punishment, cancellation of application for or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc., recorded in the scientific research integrity untrustworthy file, given scientific research integrity admonition talk, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Effects of miR-223 on colorectal cancer cell proliferation and apoptosis through regulating FoxO3a/BIM" by Ju Hui of The Affiliated Hospital of Qingdao University is the corresponding author and first author. After investigation, the paper was found to be fraudulent. Ju Hui should be dealt with as follows: 1 year of demerit punishment, cancellation of application for or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc., recorded in the scientific research creditworthiness untrustworthy archives, give scientific research creditworthiness admonition talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma" by Liu Hongling of the Affiliated Hospital of Qingdao University and Wang Luping as the first author. After investigation, the paper was found to be fraudulent. Liu Hongling was dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc. for 5 years, recorded in the archives of scientific research integrity untrustworthiness, given scientific research integrity admonition talks, canceled participation in this year's appraisal and appraisal, and the annual assessment must not be determined as qualified or above; Wang Luping (combined with another paper) made the following treatment: 1 year of demerit punishment Cancel the qualifications for applying for or declaring scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, and scientific and technological talent titles for 6 years, cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 6 years, record it in the archives of scientific research creditworthiness untrustworthiness, give scientific research integrity admonition talks, cancel participation in this year's appraisal and appraisal, and the annual assessment must not be determined as qualified or above.

The paper "Hispidulin induces ER stress-mediated apoptosis in human hepatocellular carcinoma cells in vitro and in vivo by activating AMPK signaling pathway", by Gao Hui of the School of Pharmacy of Qingdao University and Han Mei as the first author, after investigation, The paper was investigated for data falsification and misnaming; "Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγ" by Gao Hui as the corresponding author and Han Mei as the first author, was investigated. Gao Hui (combined with 4 other papers) is treated as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 9 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 9 years, recorded in the scientific research integrity untrustworthy file, canceled to participate in this year's appraisal of excellence, the annual assessment must not be determined as qualified or above; The following treatment is made for Han Mei: warning punishment for 6 months, cancellation of application for scientific research projects, Academic awards, honorary titles and other qualifications for 1 year, the annual assessment shall not be determined as excellent grades.

The paper "Autophagy is a pro-survival mechanism in ovarian cancer against the apoptotic effects of euxanthone" by Sun Xianghong of the Affiliated Hospital of Qingdao University and Julie as the first author. After investigation, the paper was found to be fraudulent. Sun Xianghong and Julie are dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as nominators or recommenders, nominated or recommended persons, evaluation experts, etc., recorded in the scientific research integrity untrustworthy archives, give scientific research integrity admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer" by Zhang Hui of the Affiliated Hospital of Qingdao University and Wang Luping as the first author. After investigation, the paper was found to be fraudulent. Zhang Hui should be dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 5 years, recorded in the scientific research integrity untrustworthy file, given scientific research integrity admonition talk, canceled the annual appraisal of excellence, the annual assessment must not be determined as qualified and above; Wang Luping (combined with another paper) made the following treatment: 1 year of demerit punishment, Cancel the application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 6 years, cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 6 years, recorded in the scientific research creditworthiness untrustworthy archives, give scientific research creditworthiness admonition talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

12. Sun Yong of the School of Pharmacy of Qingdao University is the corresponding author and Li Shengnan of the Affiliated Cardiovascular Hospital of Qingdao University is the first author of the paper "Cytoprotective effects of euxanthone against ox-LDL-induced endothelial cell injury is mediated via Nrf2". After investigation, the paper was falsified and improperly signed. Sun Yong was unaware of the signature of the paper. Li Shengnan was dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 5 years, recorded in the scientific research integrity untrustworthy archives, given scientific research integrity admonition talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

13. The paper "Icariin induces apoptosis in acute promyelocytic leukemia by targeting PIM1" by Wang Zhi of the Affiliated Hospital of Qingdao University and Zhang Hong as the first author. After investigation, the paper was falsified and improperly signed. Wang Zhi and Zhang Hong are to be dealt with as follows: 1 year of demerit punishment, cancellation of application for or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 5 years, cancellation of qualifications as nominators or recommenders, nominated or recommended persons, review experts, etc., recorded in the scientific research creditworthiness untrustworthy archives, give scientific research creditworthiness admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "MiR-137 suppresses tumor growth and metastasis in clear cell renal cell carcinoma" by Han Zhiwu of the Affiliated Hospital of Qingdao University and Meizhi Wang as the first author. After investigation, the paper was falsified and improperly signed. The following treatment was made for Han Zhiwu (combined with 2 other papers): 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 7 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 7 years, recorded in the archives of scientific research integrity untrustworthiness, given scientific research integrity admonition talks, canceled participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified and above; Wang Meizhi was dealt with as follows: 1 year of demerit punishment Cancel the qualifications for applying for or declaring scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, and scientific and technological talents for 5 years, cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc., recorded in the archives of scientific research creditworthiness untrustworthiness, give scientific research integrity admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Identification of profilin 1 as the primary target for the anti-cancer activities of Furowanin A in colorectal cancer" by Lv Jing of the Affiliated Hospital of Qingdao University and Jinxia Zhao as the first author. After investigation, the paper was falsified and improperly signed. Lü Jing and Zhao Jinxia were dealt with as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, and qualifications for scientific and technological talents for 5 years, cancellation of qualifications as nominators or recommenders, nominated or recommended persons, and appraisal experts for 5 years, recorded in the archives of scientific research creditworthiness untrustworthiness, given scientific research creditworthiness admonitions and talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

The paper "Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma. Journal of experimental&clinical cancer research”。 After investigation, the paper had data fraud. Gao Hui (combined with 4 other papers) is treated as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 9 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 9 years, recorded in the scientific research integrity untrustworthy file, cancel participation in this year's appraisal of excellence, the annual assessment must not be determined as qualified or above; the following treatment is made for Li Zichao: warning punishment for 6 months, cancellation of application for scientific research projects, Academic awards, honorary titles and other qualifications for 1 year, the annual assessment shall not be determined as excellent grades.

The paper "PTTG promotes invasion in human breast cancer cell line by upregulating EMMPRIN via FAK/Akt/mTOR signaling" by Han Zhiwu of the Affiliated Hospital of Qingdao University and Gao Hui of the School of Pharmacy as the first author. After investigation, the paper was found to be fraudulent. The following treatment is made for Han Zhiwu (combined with 2 other papers): 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 7 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 7 years, recorded in the scientific research integrity untrustworthy file, given scientific research integrity admonition talks, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above Gao Hui (combined with 4 other papers) is treated as follows: 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 9 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 9 years, recorded in the archives of scientific research integrity untrustworthiness, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

18. The paper "Alpinumisoflavone induces apoptosis in esophageal squamous cell carcinoma by modulating miR-370/PIM1 signaling" by Gao Hui of the School of Pharmacy of Qingdao University and Han Yantao of the School of Basic Medicine as the first author, after investigation, there is a pattern reuse behavior; Han Yantao is the corresponding author, Gao Hui's first author paper "Hispidulin suppresses tumor growth and metastasis in renal cell carcinoma by modulating ceramide-sphingosine 1-phosphate rheostat" was investigated for improper attribution and data reuse. Han Yantao was unaware of the signature of the paper. The following treatment is made for Gao Hui (combined with 4 other papers): 1 year of demerit punishment, cancellation of application or declaration of scientific and technological plan projects (special projects, funds, etc.), scientific and technological awards, scientific and technological talent title qualifications for 9 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 9 years, recorded in the archive of scientific research integrity untrustworthiness, cancel participation in this year's appraisal of excellence, and the annual assessment must not be determined as qualified or above.

19. You Jie of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine is the corresponding author and Wang Tingting is the first author of the paper "Alpinumisoflavone suppresses tumour growth and metastasis of clear-cell renal cell carcinoma". After investigation, the paper has the problem of duplicate pictures. After the paper was published, Wang Tingting applied to the editorial board of the magazine for errata on the issue of pictures, and the editorial department officially published the errata in February 2019. Wang Tingting is primarily responsible for the formation and publication of the paper (the student has left the school after graduating in April 2020); the following treatment of You Jie is as follows: Scientific research integrity admonition talk, return the relevant award.

The paper "Knockdown of long noncoding RNA DLX6-AS1 inhibits cell proliferation and invasion of cervical cancer cells by downregulating FUS" by Jia Shuhua of Changzhi Medical College and Tian Yun as the first author. After investigation, the paper has a third-party ghostwriting, falsification of data, and plagiarism. Jia Shuhua was dealt with as follows: Scientific research integrity admonition talks, cancel his qualification to declare financial fund support projects for 5 years, cancel his qualifications to participate in scientific research awards, scientific and technological talent recommendation and selection, appraisal and appraisal awards, professional title promotions, etc. for 1 year; Tian Yun was dealt with as follows: administrative warning punishment, revocation of associate professor qualifications, cancellation of his qualification to declare financial fund support projects for 5 years, and cancellation of his qualifications to participate in scientific research awards, scientific and technological talent recommendation and selection, appraisal and appraisal, and professional title promotion for 1 year.

Qin Jiangbo of the Peace Hospital Affiliated to Changzhi Medical College is the corresponding author and first author of the paper "Circular RNA hsa_circ_0000285 acts as an oncogene in laryngocarcinoma by inducingWnt/β-catenin signaling pathway". After investigation, the paper had falsified data and fabricated results. Qin Jiangbo was dealt with as follows: ordered to withdraw the manuscript, given administrative warning sanctions, cancelled his qualification to undertake financial support projects for 5 years, and cancelled his qualifications to participate in scientific research awards, scientific and technological talent recommendation and selection, appraisal and appraisal, and professional title promotion for 1 year.

22. Wang Mingquan of the Affiliated Hospital of Yan'an University is the corresponding author and Wang Aihong of the School of Medicine of Yan'an University is the first author of the paper "Long noncoding RNALUCAT1 promotes cervical cancer cell proliferation and invasionby upregulating MTA1". After investigation, the paper was found to have bought and sold papers and improperly signed the papers. The following treatment was made for Wang Mingquan: cancel the qualification for promotion of professional titles for 5 years, cancel the qualifications for recruiting graduate students for 3 years, cancel the qualifications for declaring financial fund support projects for 5 years, cancel the qualifications of nominating or recommending people, nominated or recommending people, and evaluating experts for 5 years, cancel the qualifications for applying for scientific and technological awards (achievements, honors) and scientific and technological talents for 5 years, reduce the level of professional and technical posts from level 4 to level 7, and cancel the qualifications for evaluation and evaluation for 2 years; Wang Aihong made the following treatment: cancel the qualification for promotion of professional titles for 5 years, cancel the qualifications for recruiting graduate students for 3 years, Cancel the qualifications for declaring financial fund support projects for 5 years, cancel the qualifications of nominated or recommenders, nominated or recommended people, and review experts for 5 years, cancel the qualifications for applying for scientific and technological awards (achievements, honors), and the title of scientific and technological talents for 5 years, reduce the level of professional and technical posts from five to seven, remove them from the position of director of the inspection department, and cancel the qualifications for evaluation and evaluation for 2 years; make the following treatment of other authors Zhao Jumei: scientific research integrity admonition talk, cancel the qualification for professional and technical post level promotion for 1 year, cancel the qualification for declaring financial fund support projects for 1 year, Cancel the qualifications of nominated or recommended persons, nominated or recommended people, and evaluation experts for 1 year, and cancel the qualifications for applying for scientific and technological awards (achievements, honors) and scientific and technological talents for 1 year.

23. Yu Jianping of Xianyang Hospital of Yan'an University is the corresponding author of the paper "miR-181a down-regulates MAP2K1 to enhance adriamycin sensitivity in leukemia HL-60 cells" by Yu Jianping of Xianyang Hospital of Yan'an University and Wang Jianjun of Shaanxi Provincial Nuclear Industry 215 Hospital as the first author. After investigation, the paper has academic misconduct in ghostwriting. The Shaanxi Provincial Nuclear Industry 215 Hospital made the following treatment of Wang Jianjun: admonishing the talk, canceling the qualification to undertake financial support projects for 5 years, canceling the qualifications for various types of evaluation at all levels for 3 years, canceling the professional titles and job promotion qualifications for 3 years, and returning the relevant reward amount. The Xianyang Hospital of Yan'an University made the following treatment of Jianping: admonishing the conversation, canceling the qualification to undertake financial support projects for 5 years, canceling the qualifications for various types of evaluation at all levels for 3 years, and canceling the qualifications for professional titles and job promotions for 3 years.

"Long noncoding RNA ZFAS1 acts as an oncogene by targeting miR-193a-3p in human non-small cell lung cancer. European review for medical and pharmacological sciences”。 After investigation, the paper was found to have bought and sold papers, compiled data, improperly attributed, and improperly labeled. Ge Haibo was dealt with as follows: withdrew the dissertation, revoked the doctorate, disqualified from applying for science and technology plan projects for 5 years, and given a warning sanction and criticism education within the party.

The paper "microRNA383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via down-regulating PARP2" by Hao Min of the Second Hospital of Shanxi Medical University and Teng Peng as the first author. After investigation, the paper was purchased by Teng Peng and submitted on behalf of the paper, and he was listed as the corresponding author without Hao Min's consent and forged the corresponding author's mailbox. Teng Peng was treated as follows: revoking his doctorate and Hao Min as follows: suspending the recruitment of graduate students for 2 years.

The paper "Circular RNA circ_0067934 functions as an oncogene in breast cancer by targeting Mcl-1" by Wang Jun, School of Imaging, Shanxi Medical University, and Wang Jianming, Shanxi Provincial People's Hospital (a doctoral candidate at Shanxi Medical University) as the first author. After investigation, the paper was entrusted by Wang Jianming to a third-party institution to write and cast on behalf of Wang Jianming, and Wang Jianming listed it as a corresponding author without Wang Jun's consent. Wang Jianming was dealt with as follows: demerit punishment, other treatment was carried out by his personnel unit; Wang Jun was treated as follows: Suspend the recruitment of graduate students for 2 years.

Zhao Hongli of Harbin Medical University Cancer Hospital is the first author and Yang Maopeng is the corresponding author of the paper "Long noncoding RNA MIAT promotes the growth and metastasis of non-small cell lung cancer by upregulating TDP43". After investigation, the paper was ghostwritten, cast on behalf of, and improperly signed. Zhao Hongli was dealt with as follows: ordered to withdraw the manuscript, scientific research integrity admonition talk, cancel her declaration of scientific and technological plan (special projects, funds, etc.) projects, award qualifications for 5 years, cancel the promotion of graduate supervisor qualifications for 4 years, cancel her qualification for promotion to job titles for 3 years; make the following treatment of Yang Maopeng: scientific research integrity admonition talk, revoke the scientific research award of the paper, and withdraw all bonuses, cancel his declaration of scientific and technological plan (special projects, funds, etc.) projects, award qualifications for 3 years, cancel academic degree graduate enrollment qualifications for 3 years, Conduct self-examination of the research of other members of the research group within one year to avoid similar incidents.

The paper "Long non-coding RNA DLX6-AS1 acts as an oncogene by targeting miR-613 in ovarian cancer" by you Qi of the First Affiliated Hospital of Harbin Medical University as the first author and corresponding author. After investigation, the paper was found to have been bought and sold and improperly labeled. You Qi was dealt with as follows: ordered to withdraw the manuscript, admonished the conversation on scientific research integrity, revoked the scientific research award of the paper, and withdrew all the bonuses, canceled his application for scientific and technological plans (special projects, funds, etc.) projects, award qualifications for 5 years, canceled the academic degree graduate enrollment qualifications for 3 years, cancelled his qualifications for promotion to job titles for 3 years, and conducted self-examination of the research of other members of the research group within a time limit of 1 year to avoid similar things.

The paper "Circular RNA hsa_circ_0011946 promotes cell growth, migration, and invasion of oral squamous cell carcinoma by upregulating PCNA" by Meng Yan of the Fourth Affiliated Hospital of Harbin Medical University and Bi Liangjia as corresponding author. After investigation, the paper was found to have bought and sold papers, ghostwritten, and improperly signed. Meng Yan was dealt with as follows: ordered to withdraw the manuscript, scientific research integrity admonition talk, cancel his declaration of scientific and technological plan (special projects, funds, etc.) projects, award qualifications for 5 years, cancel the qualification for promotion to graduate tutor for 4 years, cancel his qualification for promotion to job titles for 3 years; make the following treatment of Bi Liangjia: scientific research integrity admonition talk, cancel his declaration of scientific and technological plan (special projects, funds, etc.) projects, reward qualifications for 3 years, cancel academic degree graduate enrollment qualifications for 3 years, and conduct self-examination of the research of other members of the research group within a time limit of 1 year, Avoid the same kind of thing.

Zhong Zhenbin of the Affiliated Cancer Hospital of Harbin Medical University is the first author and Ge Xiaofeng is the corresponding author of the paper "Knockdown of long noncoding RNA DLX6-AS1 inhibits migration and invasion of thyroid cancer cells by upregulating UPF1". After investigation, the paper was ghostwritten, cast on behalf of, and improperly signed. Zhong Zhenbin was dealt with as follows: ordered to withdraw the manuscript, scientific research integrity admonition talk, cancel his declaration of scientific and technological plan (special projects, funds, etc.) projects, award qualifications for 5 years, cancel the qualification for promotion to graduate tutor for 4 years, cancel his qualification for promotion to job titles for 3 years; make the following treatment of Ge Xiaofeng: scientific research integrity admonition talk, cancel his declaration of science and technology plan (special projects, funds, etc.) projects, reward qualifications for 3 years, cancel academic degree graduate enrollment qualifications for 3 years, and conduct self-examination of the research of other members of the research group within a time limit of 1 year. Avoid the same kind of thing.

31. Shanghai Pulmonary Hospital (2015 clinical doctoral candidate of the First Affiliated Hospital of Soochow University) Chen Bin is the first author and the corresponding author of the First Affiliated Hospital of Soochow University Ling Chunhua's paper "Long noncoding RNA AK027294 acts as an oncogene in non-small cell lung cancer by up-regulating STAT3". After investigation, the paper was found to have bought and sold papers. Chen Bin was dealt with as follows: revoking his doctorate; And dealing with Ling Chunhua as follows: admonishing him to talk, suspending the recruitment of various types of graduate students for 1 year, and stopping applying for qualifications such as scientific research projects, scientific and technological awards, scientific and technological talents and professional and technical position promotions for 2 years.

32. The paper "Macrophage-derived exosomes mediate osteosarcoma cell behavior by activating AKT signaling" by Yan Bin as the first author and Xu Yaozeng of the First Affiliated Hospital of Soochow University as the corresponding author. After investigation, the paper was found to have bought and sold papers. Yan Bin was dealt with as follows: terminate his study qualifications; Xu Yaozeng was dealt with as follows: criticizing education, stopping the recruitment of clinical doctoral students for 1 year, and stopping applying for qualifications such as scientific research projects, scientific and technological awards and scientific and technological talents for 1 year.

Feng Feng of Shandong First Medical University is the corresponding author and first author of the paper "Long noncoding RNA SNHG16 contributes to the development of bladder cancer via regulating miR-98/STAT3/Wnt/β-catenin pathway axis". After investigation, the paper had tampered with data and improperly signed it. Feng Feng was dealt with as follows: scientific research integrity admonition talk, cancellation of participation in the current year's appraisal of the qualifications, annual assessment shall not be determined as excellent grade, cancellation of application or declaration of science and technology plan project qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert and other qualifications for 5 years.

The paper "LncRNA XIST inhibits ovarian cancer cell growth and metastasis via regulating miR-150-5p/PDCD4 signaling pathway" by Wang Shuli of Shandong First Medical University and Li Guanzhen as corresponding author. After investigation, the paper had data tampering. Li Guanzhen was dealt with as follows: Scientific research integrity admonition talks, cancellation of participation in the current year's appraisal of the qualifications, annual assessment shall not be determined as excellent grade, cancellation of application or declaration of science and technology plan project qualifications for 3 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc. for 3 years; Wang Shuli was treated as follows: scientific research integrity admonition talk, cancel the qualification to participate in the annual appraisal of excellence, the annual assessment shall not be determined as excellent grade, cancel the application or declaration of science and technology plan project qualifications for 3 years, Disqualification as a nominator or recommender, nominated or recommended person, review expert, etc. for 3 years.

The paper "MicroRNA-30bResibufogenin suppresses tumor growth and Warburg effect through regulating miR-143-3p/HK2 axis in breast cancer" by Guo Ying of Shandong First Medical University and Corresponding Author Zhao Jian. After investigation, the paper has falsified data, ghostwritten, and cast on behalf of others. Zhao Jian was dealt with as follows: Scientific Research Integrity Admonition Talk; Guo Ying was dealt with as follows: Scientific Research Integrity Admonition Talk, cancel the qualification to participate in the current year's appraisal, the annual assessment shall not be determined as excellent grade, the application or declaration of science and technology plan project qualifications for 3 years, and the disqualification as a nominator or recommender, nominated or recommended person, and evaluation expert for 3 years.

36. The paper "Euxanthone Ameliorates Sevoflurane-Induced Neurotoxicity in Neonatal Mice" by Zhou Hui of Shandong First Medical University and Wang Gongming as the corresponding author. After investigation, the paper had data tampering. The following treatment was made for Wang Gongming: scientific research integrity admonition talks, cancellation of participation in the current year's appraisal of the qualifications, annual assessment shall not be determined as excellent grade, cancellation of application or declaration of science and technology plan project qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, review expert, etc.; Zhou Hui was treated as follows: scientific research integrity admonition talk, cancel the qualification to participate in the current year's appraisal, the annual assessment shall not be determined as excellent grade, cancel the application or declaration of science and technology plan project qualifications for 5 years, Disqualification as a nominator or recommender, nominated or referrer, review expert, etc. for 5 years.

Physcion 8-O-β-glucopyranoside Induces Apoptosis, Suppresses Invasion and Inhibits Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma HepG2 Cells”。 After investigation, the paper had data tampering. Zhang Jie made the following treatment: scientific research integrity admonition talk, cancel the qualification to participate in the annual appraisal of excellence, the annual assessment shall not be determined as excellent grade, the application or declaration of scientific and technological plan project qualifications for 5 years, the cancellation of qualifications as a nominator or recommender, the nominated or recommended person, the appraisal expert, etc. for 5 years, the use of this article to make profits, the revocation of the qualification of the deputy senior title; the following treatment is made of Wang Qiangzuo: scientific research integrity admonition talk, cancel the qualification to participate in the current year's appraisal, and the annual appraisal must not be determined as an excellent grade. Cancel the qualifications for applying for or declaring science and technology plan projects for 5 years, cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 5 years, revoke the profits from this article, recover the bonuses obtained, revoke the qualifications of chief physicians, withdraw the evaluation materials of the Famous Old Chinese Medicine Talent Project in Shandong Province, and suspend the enrollment qualifications of graduate tutors for 1 year.

The paper "Physcion 8-O-β-glucopyranoside Suppresses the Metastasis of Breast Cancer in Vitro and in Vivo by Modulating DNMT1" by Chen Xia of Shandong First Medical University as the first author and Li Fuxia as the corresponding author. After investigation, the paper had tampered with data and improperly signed it. Li Fuxia was dealt with as follows: Scientific research integrity admonition talks, cancellation of participation in the annual appraisal of the qualifications, annual assessment shall not be determined as excellent grade, cancellation of application or declaration of science and technology plan project qualifications for 5 years, cancellation of qualifications as a nominator or recommender, nominated or recommended person, evaluation expert, etc. for 5 years; Chen Xia was treated as follows: Scientific research integrity admonition talk, cancel the qualification to participate in the annual appraisal of excellence, the annual assessment shall not be determined as excellent grade, cancel the application or declaration of science and technology plan project qualifications for 5 years, Cancel the qualifications as a nominator or recommender, nominated or recommended person, review expert, etc. for 5 years, revoke the profits from the use of this article, recover the bonus obtained, and revoke the qualification of deputy chief nurse.

Yangtze University Wei Huawei's paper "miR-101 affects proliferation and apoptosis of cervical cancer cells by inhibition of JAK2". After investigation, there is a behavior of tampering with data and charts. The following treatment was made for Wei Hua: the qualification for the achievement level of the thesis in the school was cancelled, and the paper could not be used for awards, year-end assessment, employment period assessment, title review, etc., and the application qualification for scientific research projects was cancelled for 3 years.

40. The paper "Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding" by Liu Jing of the Eighth People's Hospital of Jinan (formerly Laiwu Iron and Steel Group Co., Ltd.) and Wang Gang of Shandong Provincial Entolaryngology Hospital (West Branch of Shandong Provincial Hospital) as the first author RNA-CHRF”。 After investigation, the paper had academic misconduct in buying and selling papers. Shandong Provincial ENT Hospital made the following treatment of Wang Gang: admonishment to talk, cancel the title and job promotion qualifications for 3 years, cancel the qualifications for appraisal and excellence for 5 years, cancel the declaration of scientific research projects, scientific research awards, scientific and technological achievements, scientific and technological talent plans, etc. for 5 years; the Eighth People's Hospital of Jinan City made the following treatment of Liu Jing: retraction, exhortation talk, revocation of projects in the hospital, cancellation of professional titles and job promotion qualifications for 5 years, cancellation of qualifications for evaluation of first tree excellence for 5 years, cancellation of declaration of scientific research projects, scientific research awards, scientific and technological achievements, The qualifications of the scientific and technological talent plan are 5 years; the other authors Wang Ping and Yan Xiaojun are dealt with as follows: admonishing the conversation, revoking the projects approved in the hospital, canceling the qualifications for the evaluation of the first tree for 3 years, and canceling the qualifications for declaring scientific research projects, scientific research awards, scientific and technological achievements, and scientific and technological talent programs for 3 years.

41. The paper "miR-155 Affects Osteosarcoma MG-63 Cell Autophagy Induced by Adriamycin Through Regulating PTEN-PI3K/AKT/mTOR Signaling Pathway" by Xiong Min of Dongfeng General Hospital of Sinopharm and Wang Lin as the first author. After investigation, the paper has academic misconduct such as purchasing experimental data and writing on behalf of others. Wang Lin was dealt with as follows: Retract the manuscript, return the awards that have been issued to the papers, cancel the qualifications for all kinds of scientific research projects, talent projects, and scientific and technological awards at all levels for 5 years, cancel the qualifications for appraisal and appraisal for 5 years, cancel the qualifications for declaring professional titles for 5 years, revoke the scientific research projects that use the thesis to conclude the topic, and deduct quarterly performance; Xiong Min should be dealt with as follows: admonishing the conversation, suspending the qualifications for appraisal and appraisal for 1 year, canceling the qualifications for all kinds of scientific research projects, talent projects, and scientific and technological awards at all levels for 1 year; for other authors Tang Bing, Han Heng, Mao Dan, Chen Jie, Zeng Yun made the following treatment: admonishing the conversation, canceling the qualifications for all kinds of scientific research projects, talent projects, scientific and technological awards at all levels for 1 year.

42. Feng Ye of China-Japan Friendship Hospital of Jilin University is the corresponding author, and Yin Dexin and Li Yezhou are the first authors of the paper "Pro-Angiogenic Role of LncRNA HULC in Microvascular Endothelial Cells via Sequestrating miR-124". After investigation, the paper has the behavior of buying and selling the paper data. Yin Dexin (combined with 6 other papers) was treated as follows: lifetime cancellation of science and technology plan projects (special projects, funds, etc.) application qualifications, cancellation of various awards and appraisal qualifications for 2 years, cancellation of positions, professional titles and promotions of valid declaration qualifications once, withholding post allowances for 24 months, prohibiting participation in graduate student enrollment qualification review for 3 years, and revoking the positions of deputy chief physician and associate professor; Li Yezhou (merged with 1 other paper) made the following treatment: cancel the application qualifications for science and technology plan projects (special projects, funds, etc.) for 6 years, Cancel all kinds of awards and appraisal qualifications for 2 years, cancel the effective declaration qualifications for job and title promotion once, withhold post allowances for 24 months, prohibit participation in the graduate school enrollment qualification review for 2 years, as a registered graduate student, give the punishment of staying in the university probation; Feng Ye (combined with another paper) to make the following treatment: cancel the scientific and technological plan project (special projects, funds, etc.) declaration qualifications for 6 years, cancel all kinds of awards and appraisal qualifications for 2 years, cancel the effective declaration qualifications for job and title promotion once, and withhold post allowances for 24 months. It is forbidden to participate in the graduate admissions qualification review for 2 years.

43. Wang Yang of the China-Japan Friendship Hospital of Jilin University is the corresponding author and first author of the paper "LncRNA GAS5 Represses Osteosarcoma Cells Growth and Metastasis via Sponging MiR-203a". After investigation, the paper has the behavior of buying and selling the paper data. Wang Yang (merged with 11 other papers) was treated as follows: lifetime cancellation of the application qualifications for science and technology plan projects (special projects, funds, etc.), cancellation of various awards and appraisal qualifications for 2 years, cancellation of the effective declaration qualifications for positions and professional titles and promotions once, withholding post allowances for 24 months, and lifetime prohibition from participating in the graduate school enrollment qualification review; Other author Kong Daliang (combined with 4 other papers) made the following treatment: Cancel the application qualifications for science and technology plan projects (special projects, funds, etc.) for 6 years, Cancel all kinds of awards and appraisal qualifications for 2 years, cancel the effective declaration qualifications for positions and professional title promotions once, withhold post allowances for 24 months, prohibit participation in the qualification review of graduate school enrollment for 2 years, and revoke the positions of deputy chief physician and associate professor.

44. Sun Dajun of China-Japan Friendship Hospital of Jilin University is the corresponding author, Yin Dexin of China-Japan Friendship Hospital of Jilin University, and Fu Changgeng of Dongfang Hospital of Beijing University of Traditional Chinese Medicine are the first authors of the paper "Silence of lncRNA UCA1 Represses the Growth and Tube Formation of Human Microvascular Endothelial Cells Through miR-195". After investigation, the paper has the behavior of buying and selling the paper data. Yin Dexin (merged with 6 other papers) was treated as follows: lifetime cancellation of the application qualifications for science and technology plan projects (special projects, funds, etc.), cancellation of various awards and evaluation qualifications for 2 years, cancellation of posts and title promotions once, withholding post allowances for 24 months, prohibiting participation in the qualification review of graduate school enrollment for 3 years, and revoking the positions of deputy chief physician and associate professor; Sun Dajun (combined with 3 other papers) made the following treatment: Cancel the application qualifications for science and technology plan projects (special projects, funds, etc.) for 6 years, Cancel the qualifications for various awards and appraisals for 2 years, cancel the valid declaration qualifications for the promotion of posts and titles once, withhold the post allowance for 24 months, and prohibit participation in the graduate enrollment qualification review for 2 years; deal with Chang Geng (combined with 2 other papers) to make the following treatment: As a registered graduate student, he is given the punishment of probation.

Ligustrazine Inhibits Growth, Migration and Invasion of Medulloblastoma Daoy Cells by Up-Regulation of miR-211 by Li Dongyuan of China-Japan Friendship Hospital of Jilin University is the corresponding author and Xu Donghui is the first author. After investigation, the paper has the behavior of buying and selling the paper data. Xu Donghui (merged with another paper) was treated as follows: cancel the qualification for the declaration of science and technology plan projects (special projects, funds, etc.) for 6 years, cancel the qualifications for various awards and appraisals for 2 years, cancel the valid declaration qualifications for job and title promotion once, withhold post allowances for 24 months, and prohibit him from participating in the graduate enrollment qualification review for 2 years; Li Dongyuan (merged with another paper) was treated as follows: cancel the qualifications for the declaration of science and technology plan projects (special projects, funds, etc.) for 5 years, and cancel the qualifications for various awards and appraisals for 2 years. Cancel the effective declaration of qualifications for job and title promotion once, withhold post allowance for 12 months, prohibit participation in the graduate school enrollment qualification review for 1 year, and revoke the post of chief physician; the following treatment is made for other authors Chi Guonan (combined with 2 other papers): cancel the qualifications for science and technology plan projects (special projects, funds, etc.) for 5 years, cancel the qualifications for various awards and evaluations for 2 years, cancel the effective declaration qualifications for job and title promotion once, withhold the post allowance for 12 months, and prohibit participation in the graduate enrollment qualification review for 1 year.

46. Lin Ding of Changsha Aier Eye Hospital is the corresponding author, Huang Xuetao of the First Affiliated Hospital of Zhengzhou University, and Wang Bin of Huaihe Hospital of Henan University are the first authors of the paper "Total glucosides of paeony suppresses experimental autoimmune uveitis in association with inhibition of Th1 and Th2 cell function." in mice”。 After investigation, the paper has ghostwritten and submitted, plagiarized, fabricated research processes, violated scientific and technological ethics norms, and violated the signature norms. The First Affiliated Hospital of Zhengzhou University dealt with Huang Xuetao as follows: admonished him to talk, cancel the qualification for appraisal and appraisal for 3 years, postpone the promotion of professional titles for 3 years, cancel the qualifications for declaring scientific and technological plan projects at all levels supported by financial funds, scientific and technological awards, and the title of scientific and technological talents for 5 years, and revoke the approved henan provincial health commission and hospital joint construction projects; the Huaihe Hospital of Henan University made the following treatment of Wang Bin: Cancel the qualification for appraisal and appraisal for 3 years, postpone the promotion of professional titles for 1 year, and cancel the declaration of scientific and technological plan projects and scientific and technological awards at all levels supported by financial funds 3 years of qualifications such as the title of scientific and technological talents, limited to 3 years as a nominator or recommender, nominated or recommended person, review expert, etc.; Changsha Aier Eye Hospital made the following treatment of Linding: admonishment talk, cancel the application or declaration of science and technology plan projects, science and technology awards and other qualifications for 1 year.

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"A hundred years of youth, together to the future."

Peking Union Medical College Hospital 2022 Chinese New Year Gala

Countdown to 1 day!

The "Medical Community" video number invites you to watch!

On January 30, 20:00 p.m., it will be online on time

For the country's hard-working and busy medical staff

Sincere wishes, auspicious Year of the Tiger!

Source: Health Community

Editor-in-charge: Wei Xiaoning

Proofreader: Zang Hengjia

Plate making: Xue Jiao

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