Do you believe in the Light?
Light may also cause cancer cells to die of light!
Recently, an old man in Nantong, Jiangsu Province, has gained a new life because of a new cancer treatment method - photodynamic therapy, without surgery, relying only on a beam of light to kill tumors that cannot be operated on.
First, without surgery, a beam of light accurately kills tumors that cannot be operated on
Chen Abo, 78, suddenly appeared a month ago when he ate and "couldn't swallow", and could only barely eat some liquid food, and often felt nausea in his stomach. Unable to eat and sleep, Chen Abo's body became more and more emaciated and weak, so his family took him to the hospital for treatment. Finally, it was diagnosed by gastroscopy that esophageal cancer was accompanied by stenosis, and if it is not treated in time, it will further affect the quality of life of Chen Laobo.
Given Chen's advanced age and previous history of copernic emphysema, traditional surgery, radiotherapy, and chemotherapy may be intolerable. After discussion by the expert group, it was decided to take tumor photodynamic therapy for patients.
After consultation with Chen Laobo and his family, the treatment arrived as scheduled. Before treatment, Chen Abo needs to receive a photosensitizer injection under light protection conditions. After 48 hours, enter the operating room of the endoscopic center, and under endoscopic guidance, a slender optical fiber is sent to the tumor segment of Chen Laobo's esophagus cavity for laser irradiation, killing tumor cells with high selectivity.
Image source: National Party media information public platform
The whole treatment process went smoothly and Lao Bo Chen's tolerance was good. After a re-examination a day after the operation, Chen Abo's laser-treated tumor tissue had shown necrosis and shedding. After a week, Chen Abo's symptoms gradually eased.
Second, it can make cancer cells "see light death"! What is photodynamic therapy?
Can you kill cancer cells with "a beam of light"? What exactly is the magic technology of photodynamic therapy?
According to Zhang Jianhua, director of the Department of Thoracic Surgery of Shenzhen Hospital of Southern Medical University, this new technology is a photosensitization reaction with aerobic molecules participating in accompanying biological effects. Just like basking in the sun, ordinary people do not respond, but the skin of light-sensitive people will become red, rashes, and tumor tissue that absorbs photosensitizers is like a person sensitive to light, and chemical action can occur through light, which will gradually necrotic tumor cells and reduce the damage of ordinary tissues.
As a new tumor treatment method, photodynamic technology has the characteristics of good tissue selectivity, high precision, small trauma and short treatment time, which is very suitable for the treatment of epidermal and tubular tumors. How does the photodynamic specific treatment process work?
Step 1: Determine the appropriate patient and inject the photosensitizer intravenously to avoid light. After 48 hours, the photosensitizer will be selectively concentrated in the tumor tissue for the first laser irradiation.
The second step: select the appropriate optical fiber, probe into the patient's body, laser irradiation chemical reaction, destroy and kill tumor cells.
Step 3: After 72-96 hours, endoscopic removal of necrotic tissue and observation of lesions, if necessary, the second laser irradiation is required, and the postoperative treatment should be strictly protected from light.
Third, Chinese experts refresh photodynamic therapy!
The three elements of photodynamic therapy are: photosensitizers, irradiated light and oxygen. This shows that in the process of photosensitivity, a large amount of oxygen is required to maintain, but the microenvironment in which the solid tumor is located is often an anaerobic environment, which greatly affects the lethality of photodynamic therapy.
In order to make up for this situation, recently, Academician Peng Xiaojun of the State Key Laboratory of Refinement of Dalian University of Technology conducted a new construction experiment on photosensitizers, and created a new type III mechanism of photosensitizer - NBEX, which realized the direct use of light energy to destroy RNA in tumor cells to achieve the effect of killing tumor cells, breaking through the shackles of relying on oxygen for tumor treatment.
In addition, NBEX can also induce dendritic cell maturation to a certain extent, and promote the immune response like tumor vaccines, and at present, this scientific research result has been published to the well-known international journal Cell sub-journal Chem.
Now that the new technology is more mature and more reliable, what is even more surprising is that its scope of treatment is not limited to cancer.
Fourth, a variety of cancer patients are available! Not limited to tumors
Photodynamic therapy has achieved impressive results in the treatment of malignant tumors, but it can be applied to the treatment of a variety of diseases at the same time, bringing good news to many patients who are difficult to cure.
1. Gastrointestinal tumors: esophageal cancer, stomach cancer, colon cancer and precancerous lesions, bile duct cancer, but the lumen is not completely obstructed.
2. Lung cancer: central lung cancer, early lung cancer, superficial lesions, diameter
3. Head and neck tumor: local recurrence of nasopharyngeal carcinoma after radiotherapy, oral cancer, laryngeal cancer.
4. Urinary tumors: bladder cancer, prostate cancer.
5. Gynecologic tumors: cervical cancer, endometrial cancer.
6. Skin cancer
In addition, patients with oral mucosal leukoplakia, severe atypical hyperplasia, genital warts, and psoriasis can also benefit from photodynamic therapy.
Photodynamic therapy, which requires no surgery during treatment, is simple to operate, and can be used alone or in combination with other therapies. This "anti-cancer artifact" has greatly improved the tumor cure rate, provided new choices for the majority of tumor patients, and brought new hope.
Resources:
[1] "Nantong: Septuagenarian esophagus is blocked by tumors, doctors use "a beam of light" to accurately kill cancer cells". National Party Media Information Public Platform.2021-09-29
[2] International Concern! The Liaoning academician team has made a major breakthrough in tumor treatment, or can be used as a tumor vaccine! 》. Admissions Office of Dalian University of Technology.2021-12-06
[3] "Photodynamic therapy brings light to lung cancer patients". Zheng Da First Affiliated Hospital Zheng Dong Branch Respiratory Third Department.2020-11-15
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