Albendazole, also known as propylthiazole, is the most commonly used insecticide drug additive in developed countries such as Japan and Europe, is the only anti-parasitic drug approved by the United States that can be used as a feed additive, and is also an insecticide drug approved by the Ministry of Agriculture of China for production-grade green food.
It has a strong repellent effect on most nematodes and their larvae in a variety of animals, and is a promising broad-spectrum, efficient and low-toxicity new benzimidazole deworming drug. There are also good therapeutic effects on the infection of sheep double-mouthed trematodes and large trematodes. Bovine tumor flukes are also particularly sensitive to adult and larvae of the mouthworm. For monoz tapeworm in anti-color animals, conventional doses have a good effect. It can effectively repel most of the parasites in the pig gastrointestinal tract, especially for swine roundworms than the effect of salivary imidazole. It has an equal repellent effect on roundworms, porcine roundworm stomach worms, esophageal nematode nodules and round nematodes in the adult stage of sexual maturity. The repellent effect of continuous medication on whipworms is achieved. This product is also effective in the expulsion of kidney worms and lung nematodes. It has a good effect on the expulsion of hookworms, roundworms, whipworms and tapeworm bandworms in dogs and cats, and can effectively repel gastrointestinal and respiratory parasites such as roundworms and capillaries in poultry. Zoo animals such as zebras, bears, anti-self-propelled animals, carnivores, poultry, reptiles and amphibians can be used to repel digestive tract nematodes and lung nematodes. This product has a powerful killing effect on larvae and eggs. It is suitable for expelling adult and larvae of gastrointestinal nematodes in cattle, horses, pigs and sheep, and has the advantages of wide deworming spectrum, low toxicity, good tolerance, good palatability and wide safety range. It ranks first in the United States for swine anthelmintic drugs and is most widely used in countries and regions such as the European Union, Japan and South Korea.
Effect of the compound ivermectin albendazole on different animals
Horse injection or internal administration
It is highly effective against equine paracaria, equine tip-tail nematode, equine round nematode, toothless circular nematode, common round nematode, trilodate nematode, esophageal tooth nematode, Wechsler roundworm, small roundworm, large-mouthed delinus, fly flex nematode, small-mouthed flitisiae, Ann's reticuling nematode, adult and larvae. In addition, it also has a good repellent effect on the various stages of the larvae, tapeworm and trematodes of the onchocercia microfilar and stomach flies.
Cows, sheep
Ivermectin has a good deworming effect on osterta nematodes, blood spear nematodes, cooper nematodes, roundworms, fine-necked nematodes, Marshall nematodes, esophageal nematodes, cattle-backed nematodes, sheep-backed nematodes, Shabert nematodes, reticule nematodes, tochinedia bovine, trichoan nematodes, tapeworms, and schistosomiasis. It also has good effect on cattle and sheep parasites, such as cattle skin flies, sheep nose flies, scabies snails, itchy lice, hair lice, blood lice, and hired lice.
pig
It is highly effective against posterior roundworm, pig roundworm, toothed crown-tailed nematode, esophageal nematode, porcine serous filariae, ringworm, tapeworm, trematodes, adult red-tongued roundworm and posterior circularoid larvae. In addition, it also has an excellent killing effect on ectoparasites such as pig scabies snails and pig blood lice.
Dogs, cats
Ivermectin is effective on adult hook-mouth nematode adults and larvae, canine filarial microfilares, fox whipworms, adult toxomatocarins and intestinal larvae, lion toxocaria, tapeworms, trematodes, cat toxomatosis, and canine cats with itchy snails and scabies.
other
It is highly effective for rabbit scabies snails, itch snails, poultry plumer lice, tapeworms, and trematodes. In addition, it has a killing effect on disease-transmitting arthropods such as crickets, mosquitoes, kuhao, flies, etc. and interferes with spawning or degeneration.
After oral administration of albendazole, the absorption is slow in the ruminants and slightly faster in the monogastric animals. The peak time after internal service is 24 hours, sheep are 2 to 3 days, piglets are 8-12 hours, and cattle and sheep are 24-30 hours. The pharmacokinetics of ivermectin varies according to animal species, dosage form, and route of administration. Monogastric animals can be absorbed by internal administration, but when the animals only absorb, the bioavailability of sheep rumen administration is that the bioavailability of subcutaneous injection is higher than that of internal administration, but internal administration is more rapidly absorbed than subcutaneous injection. After absorption, it can be well distributed to most tissues, but it is not easy to enter the cerebrospinal fluid. Some doses can be excreted through the milk of the lactating mother
Adverse reactions:
At conventional doses, albendazole generally does not produce adverse reactions, but due to the release of antigens by dead parasites, anaphylactic reactions can be secondary, especially at high doses. Ivermectin is lowly toxic and safe, but it is prone to to bow intoxication when injected intramuscularly or intravenously. Therefore, subcutaneous injection is often recommended, but the reaction of dogs and horses is more severe when injected. Most dogs are safe to take internally, but the English Shepherd is sensitive to ivermectin and has serious adverse reactions when it reaches, but it is safe to take ivermectin to shrimp, fish and aquatic organisms. Evie
When mycotin is poisoned, it can be detoxified with indoxin. When used to treat the serpentine butterfly, larvae such as killing can cause paralysis or obstruction in the spinal canal and salivation or flatulence in the esophagus. Birds can cause death, lethargy, or loss of appetite
Why choose powders?
From the perspective of dosage form, the injection can only be used for subcutaneous injection, not intravenous injection, the irritating response is larger during intramuscular injection, and the subcutaneous operation is troublesome, which is not conducive to simultaneous administration of large groups. Powder in the form of oral or mixed drug administration, can provide convenience for different livestock and poultry medication, especially for large groups of individual administration is more practical, large groups of animals at the same time is conducive to the purification of the entire farm parasites, reduce the cost of medication, improve feed remuneration, promote the rapid growth of individuals, improve the economic benefits of breeding.
Why choose a combination of ivermectin albendazole?
Albendazole is the only drug that can kill both adult insects and eggs and larvae at various stages of all deworming drugs, which can drive away parasitic worms in a variety of animals, and its repellent effect is reliable and clean.
Ivermectin focuses on nematodes and arthropod parasites in the skin in animals, but is ineffective against trematodes and tapeworms. And long-term use is easy to resist drugs, albendazole is effective against nematodes, trematodes, tapeworms in animals, but ineffective against arthropod parasites parasites parasites in the skin. Therefore, the anthelmintic drug is selected from the compound preparation of ivermectin albendazole, and the deworming is thorough at one time. Albendazole and ivermectin can complement and strengthen the spectrum of exorcism parasites, and then can comprehensively and thoroughly kill parasites inside and outside livestock and poultry, so as to achieve good deworming effect.
Master the principle of insecticide and know why it is so.
The principle of action of ivermectin is to interfere with γ-aminobutyric acid, resulting in the death of nerve paralysis in arthropods (mosquitoes, mites, ticks, etc.), why can't ivermectin kill trematodes and tapeworms, because flukes and tapeworms do not use γ monoaminobutyric acid as neurotransmitters. Why it is safe is because the peripheral neurotransmitter of pigs, cattle and sheep is acetylcholine, not γ mono-aminobutyric acid. Although the central neurotransmitter is γ aminobutyric acid, because of the presence of a blood-brain barrier, the drug will not have an effect and is therefore safe. Fenbendazole is an energy inhibitor, a protein inhibitor, and is highly selective against insects, so it is also safe.
Ivermectin is mainly excreted with feces and also with milk, so it should not be used in lactating cattle
Saiwei compound ivermectin albendazole premix, suitable for a variety of animals, a bag of 1kg, safe to use, the effect is exact. High-quality animal protection breeding consultation private message message.