Recently, the domestic local new crown pneumonia epidemic has spread to many provinces and cities, in addition to attaching importance to the prevention and control of the epidemic, the role of traditional Chinese medicine in the treatment of new crown pneumonia has also attracted people's attention.
The latest issue of the "Mycology" sponsored by the Institute of Microbiology of the Chinese Academy of Sciences and the Chinese Mycological Society published an article entitled "Research on the Inhibition of Lung Inflammation and The Relief of Pulmonary Fibrosis by Cordyceps Militaris Powder Capsules", written by Xu Yujun from the School of Medicine of Nanjing University in Jiangsu Province and Cao Peng from the Affiliated Hospital of Integrated Traditional Chinese and Western Medicine of Nanjing University of Traditional Chinese Medicine.
Mycosmology
Cordyceps militaris powder inhibits lung inflammation and relieves pulmonary fibrosis
Coronavirus disease (COVID-19), caused by SARS-2 infection, has created a global pandemic and poses a major threat to world public health. Clinical data show that the important reason for the exacerbation of the condition of many patients with severe new coronary pneumonia may be the overreaction of the immune system, which causes a serious "cytokine storm" and an uncontrolled inflammatory response in the later stages of the disease.
New crown pneumonia is an acute viral infectious disease, the course of the disease is relatively short, resulting in a relatively low probability of development of pulmonary fibrosis, especially in mild cases, most of which do not appear pulmonary fibrosis. However, in severe and critical cases, pulmonary fibrosis may occur. Because the lungs of severely ill and critically ill patients will have obvious inflammation and damage, a large number of inflammatory cells will appear, fibrous tissue hyperplasia will occur during the repair process, and some fibrous tissue will remain in severe cases.
The above study confirmed through mouse animal experiments that the traditional Proprietary Chinese medicine Cordyceps militaris powder can alleviate the symptoms of lung inflammation and fibrosis induced by the s protein group of the new acute respiratory syndrome Coronavirus type 2 (SARS-co-2) and the bacterial lipopolysaccharide (lp5).
Cordyceps militaris is a complex of ovary and insect body of the fungus Pupae of the family Ergoidaceae that parasitizes insects in the family Noctuidae, and is one of the important edible and medicinal fungi in China. In recent years, it has been found that Cordyceps and its main active ingredients can play a role in treating lung diseases by regulating the body's immune antioxidant and inhibiting the inflammatory response.
The article further points out that acute and chronic inflammation tends to trigger fibrosis, while artificially cultivated Cordyceps militaris extract has a strong anti-fibrosis effect, and its effect is superior to that of natural Cordyceps sinensis.
The research results have been verified in clinical applications
"Cordyceps militaris capsules are actually an old medicine with wide clinical applications. It is a traditional Chinese medicine based on the lung and kidney meridians, which is mainly used to supplement the deficiency, and we will use it in the clinic for some patients with respiratory diseases with qi deficiency. Professor Lin Lin, director of the Department of Respiratory and Critical Care Medicine of Guangdong Provincial Hospital of Traditional Chinese Medicine, was not surprised by the above research results in an interview with the Southern Daily reporter.
Professor Lin Lin, Director of the Department of Respiratory and Critical Care Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine
Chinese medicine believes that the key pathogen of the "cytokine storm" caused by the new acute respiratory syndrome coronavirus type 2 (sars-co-2) is "mutual obstruction of toxic stasis, lung qi decay", treatment should be "detoxification and stasis, great supplementation of lung qi", targeted dialectical treatment may be the opportunity for Chinese medicine to treat new crown pneumonia.
Professor Lin Lin pointed out that in the clinic, pneumonia, COPD, asthma and even lung cancer and other lung disease patients will have lung qi deficiency in the later stage, so in the recovery stage of these lung diseases, you can use proprietary Chinese medicines such as Cordyceps militaris capsules to supplement lung qi, thereby promoting the recovery of the disease. "This is also suitable for severe COVID-19 patients."
Pulmonary fibrosis, in simple terms, is that the normal tissue of the lungs is replaced by over-proliferating fibrous tissue and loses its proper function, which is the final outcome of a variety of lung diseases. The cause is often chronic injury, such as pneumoconiosis, chronic lung disease and so on. "For the treatment of pulmonary fibrosis, there is no specific drug, and the above research confirms that Cordyceps militaris powder can alleviate the symptoms of pulmonary fibrosis in severe new crown pneumonia, which also enhances our confidence in clinical medication." According to Professor Lin Lin, in the clinic, Cordyceps militaris powder is often used for the rehabilitation treatment of patients with copernic emphysema with pulmonary fibrosis, and the patient's lung function has improved significantly, "I believe that it is also effective for pulmonary fibrosis caused by severe new crown pneumonia, and the current relevant clinical data we are still collecting." ”
【Reporter】 Ou Xujiang
【Author】 Ou Xujiang
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