Earlier talked to you a lot about the control of stomach acid medicine, today we come to talk about other gastrointestinal medications, many people are often plagued by constipation, for these people, normal row is a kind of luxury that can be encountered and can not be sought.
Many elderly people in order to be able to defecate normally, the home are often prepared with changrun tea or senna leaves, today Ziyu will talk to you about two more safe and effective laxatives than changrun tea or senna, they can make you poop no longer worry.
Who are they? It is our protagonist today, the male protagonist is polyethylene glycol, and the female protagonist is our commonly used lactulose. Why is the male protagonist polyethylene glycol and the female protagonist lactulose? Curious, then let's talk about this little couple in detail, right? About three minutes or so, interested friends will suddenly understand after reading these three minutes.
<h1 class= "pgc-h-arrow-right" > first we talk about the male protagonist polyethylene glycol. </h1>
Polyethylene glycol is a polymer with a molecular weight of 4000, so you will see that most drug boxes are written with polyethylene glycol 4000.
Its pharmacological effect in the human body is mainly dependent on its physical properties, after taking, it is not absorbed, retained in the intestine, increase the local osmotic pressure, so that water remains in the large intestine.
As we all know, the feces should remain soft and rotten, the moisture contained in it is very critical, why increase dietary fiber, can keep the stool unobstructed, in addition to it can promote gastrointestinal peristalsis, there is also an important reason is that it keeps water in the intestine. The same is true for polyethylene glycol, the osmotic pressure of feces is increased, which will reduce the absorption of water from the stool by the large intestine, increase the water content of the feces in the intestine, thereby playing a role in softening the stool and promoting its movement and excretion in the intestine.
<h1 class="pgc-h-arrow-right" > talked about the male protagonist polyethylene glycol, what is the difference between the female protagonist's lactulose? </h1>
In addition to retaining intestinal water, increasing fecal volume, stimulating colon peristalsis, and relieving constipation, lactulose can also play a role in restoring the physiological rhythm of the large intestine.
In addition, there is another advantage that lactulose is decomposed into weak acids such as lactose and acetic acid by intestinal bacteria after entering the human body, which reduces the pH of the large intestine, thereby reducing the absorption of ammonia ions produced by the intestinal mucosa during digestion. When the pH in the colon is reduced to 5, the ammonia in the blood enters the intestinal lumen from the intestinal mucosa, thereby reducing the blood ammonia.
To put it simply, in addition to softening the stool and promoting defecation, lactulose can also reduce the pH of the large intestine and reduce the absorption of ammonia through the metabolic effect of bacteria, so it can also be used for the treatment of hepatic encephalopathy.
Well, the difference between the two drugs has been said so much, I believe you are more cloudy, so why is polyethylene glycol male and lactulose is female.
This has to say that the drug characteristics of the two, compared to polyethylene glycol, lactulose it is more gentle and safe, four good tempered and gentle little girls. Compared with lactulose, polyethylene glycol has a stronger temper and a stronger effect, which I believe friends who have done colonoscopy have a deep understanding.
<h1 class="pgc-h-arrow-right" > So how should the two be chosen? </h1>
The first thing that must be said is that both are used very much in the clinic, and for ordinary people, it is no problem to choose either of the two. If the effect is not good, the two can also be used together, which means that men and women are not tired and more effective in working together, but it should be noted that polyethylene glycol can not be used continuously for more than 3 months, and lactulose has no attention in this regard.
In both, lactulose is milder, and for friends with mild and moderate chronic constipation, especially those with hypertension, poor cardiac function, renal insufficiency, severe liver disease and generalized weakness, it is recommended that milder and safer lactulose be preferred.
In addition, for children's constipation, polyethylene glycol 4000 and lactulose are available, but it is best for children under 8 years of age to use lactulose, because in China, polyethylene glycol in children under 8 years of age has no basis for safe use, so it is necessary to be more cautious when using it in such children.
In short, if you want to save your mind, the first choice of lactulose is right, but it should be noted that many lactulose instructions give advice for diabetic patients to use cautiously, and for diabetics, it is best to use it more cautiously.
The above, is the content of Ziyu today's chat with you, if you still have any questions about medication, welcome everyone to leave a message below, pay attention to Ziyu, and continue to bring you more and more useful drug knowledge.