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1, commonly used types,
Sulfadiazine sodium, sulfamethazine sodium, trimethoprim (trimethoprim), trimethoprim (sulfonamide synergist), sulfamethisoxazole (nexenomin), sulfamethoxazole sodium.
2. Indications for the drug.
According to the different characteristics of the drug, it can be used clinically to treat systemic infections (sulfonamides that are easily absorbed by the intestine), intestinal infections (intestinal difficulty absorbing sulfonamides), trauma (anti-inflammatory powder, silver sulfadiazine). In order for the sulfonamide to quickly reach an effective plasma concentration and exceed the concentration of PABA in the tissues, the first dose should be doubled. Long-term large-dose application of sulfonamides is easy to cause accumulation of poisoning, so it is required to use accurate doses, uniform mixing, and the course of treatment is appropriate for 3-5 days, generally not more than 7 days. Feeding laying hens with sulfonamides can cause a decrease in egg laying rates, soft-shelled and broken-shell eggs. Sulfonamides have a disturbing effect on the active immunity of some live vaccines, so it is not advisable to feed sulfonamides within 3 days before and after the use of vaccines.
3. The dosage of the drug
(1) Sulfa dimethoxypyrimidine sodium: use 250-500 ppm for drinking water for 6 days.
(2) Neonolamine: mainly used for serious infections of the urinary tract and respiratory tract caused by susceptible bacteria, poultry mixed feeding 0.1%-0.2%.
(3) Sulfamethazine sodium: used in gastrointestinal, respiratory tract, urinary tract infections and pasteurellosis, also has a good effect on coccidiosis, poultry mixed feeding 0.4%-0.5%, drinking water is 0.2%.
(4) Sulfadioquinoxoline sodium: anticoccidial drugs, poultry mixed feeding (per 1000kg feed) 100g, drinking water is 0.05% (50g/1000kg water), continuous use for 2-3 days, intermittent for 3 days, and then use for 3 days.
(5) Antibacterial synergist: trimethoprim poultry take 5-10mg twice daily, poultry mixed feeding 0.2%-0.4%.
(6) Dimethoxybenzyl trimethoprim (dimethoate net): mixed feeding 0.2%, that is, 200g per 1000kg of feed.
4. Compatibility of drugs:
Antibacterial synergist sulfonamides, used in a ratio of 1:5; sulfamethicil chlortetracycline penicillin; sulfamethamine tylosin, sulfaquinoxoline sodium ampherin vitamin K3 (for the treatment of coccidiosis).
When using sulfonamides, 0.05%-0.1% sodium bicarbonate should be added to drink water to ensure adequate drinking water; 0.05% vitamin K3 and double amount of B vitamins should be added to the feed.
5. Drug compatibility is contraindicated
Liquid sulfonamides should not be combined with acidic drugs (eg, vitamin C, penicillin, tetracycline).
6. The residual time of this type of drug:
7-14 days
Now high temperature and high humidity, rainy season, poultry is easy to stuffy shed caused respiratory infections, swollen head and swollen face, here to recommend the respiratory tract three golden square: Hu Dukang + pole Li Ke + Wan Hu Ning, 2 days can see the obvious effect, 4 days can control the disease.
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