<h1 class="pgc-h-arrow-right" > microcapsule suspension and microcapsulation suspension - suspension introduction Microcapsule suspension - suspension (ZC) and microcapsular suspension (CS) are controlled release dosage forms of pesticide formulation products. Microcapsular suspension - suspension is generally a compound preparation, one component microencapsulation, the other component is a suspension agent, the two are mixed together to stabilize the formation of "microcapsular suspension - suspension", microcapsular suspension is generally a single agent or compound components all microencapsulated after the formation of the preparation. Both for product quality specifications and physical and chemical properties should include:</h1>
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Product quality specifications
Physicochemical properties
appearance
Appearance (color, state of matter, odor)
Active ingredient content
density
Free active ingredient content (expressed in ≤%)
viscosity
Associated impurity content
Oxidation/reducibility
Other limiting component content
Corrosiveness to packaging materials
Acidity/alkalinity (in terms of H2SO4 or NaOH) or pH range
explosiveness
Active ingredient release rate (for sustained release agents)
flash point
Wet sieve test
/
Suspension rate
Spontaneous dispersibility
Dumping
Long-lasting foaming
Freeze-thaw stability
Thermal storage stability
At present, microcapsule pesticide suspensions are suitable for use in the following places:
1. Underground pests and underground nematodes: peanut grubs, caddisflies, ground tigers, root knot nematodes; vegetable root knot nematodes; sweet potato stem nematodes; ginger, burdock, yam stem nematodes; leeks, scallions maggots, etc.
2. Apple aphids, pear tree lice and citrus shell insects that are difficult to control during the growth period. The active ingredients of the adaptation are poisonous tick, endosulfan, avermectin, phosphorus killing, etc.
3. Insecticides, acaricides, fungicides used in the trunk branch stage of fruit trees and before bagging: the adaptable active ingredients are poisonous tick, malathion, diazinphos, phosphorus killing, pyridoxine, avermectin, flusilazole, propyclazole, nitricomazole, diazone, etc.
4, tree pests: such as tianniu, American white moth, etc., the active ingredients adapted to the adaptation are high-efficiency cypermethrin, high-efficiency cyfluthrin, avermectin, chlorpyrifos and so on.
5. Pre-bud herbicides that need to prolong the residual effect and reduce the harm of the drug, such as acetochlor, methylchloramine, butyrospermamine, isopropyloxalamine, dimethylpenthrin, heteroxanthone, sec-butylline, fluleline, ethoxyfluorother, etc.
6. Seed mixing agents: such as chlorpyrifos, octylthion, diazinphos, nitricosole, dimethazole, dimethanazole, triazolone, etc.
7. Environmental health pest control: such as high-efficiency cypermethrin, high-efficiency cypermethrin, chlorpyrifloride, diazine phosphorus, pyrimidin oxyphos, etc.
8. Pest control of grain storage, such as diazinphos, pyrimidinyl phosphorus oxide, etc.
At present, the earliest registered products of microcapsular suspension and microcapsulation suspension in China are WP62-99 25 g/l high efficiency cypermethrin microcapsulation suspension of Bcran typermethrin and PD20121230 14% chlorine insect perchlorofluoride microcapsulation suspension - suspension of Swiss Syngenta Crop Protection Co., Ltd. Since the beginning of domestic registration in 2007, 2018 was the year with the highest number of registrations for these two dosage forms, with a total of 64 products registered. At present, the active ingredients registered in China are as follows:
Microcapsulant suspension: chlorpyrifos, high-performance cypermethrin, (fine) high-performance cypermethrin, avermectin, dimerpentyl, thiazolidine, octylthion, metamidoaminoavermectin benzoate, imidacloprid chlorpyrifos, pyrazole ether ester, thiamethoxam, thiamethoxazine, Isoxonosone, bifenthrin, avi imidacloprid, chlorpyrifosone octylthion, methylpyrimidinephos, isopropylamide, acetoxin, 2-methylethylhexyl esters, S-lyoxene esters, avi chlorpyrifositis, avyrvicides, pyrazonium dimethylpentenone heteropyrifosone, Matrine pyrethroids, pyrethroids, neem, butyrosperm, cypermethrin, methylchochloramine, cholecytonitriles, imidamine, pyrimicetes, thiamethoxam, trizophosphate, proprethrene, dextromethrin, octythionin phomethrol, nicotinyl matrine, wild wheat, dimethrin isospermone, cypermethrin de-phenyl ether.
Microcapsular suspension-suspension agents: thiamethoxam • high efficiency cypermethrin, imidacloprid chlorpyrifosine, high efficiency cypermethrin chlorpyrifene , high efficiency cypermethrin thiazide , thiazoramine chlorpyrifosine , arvyl methoxychlorhydrazine , avi thiamethoxazine , thiamethoxine , butylthiavirus , fluosilzole thiostyl ester , high efficiency cypermethrin methylaminos benzoate , sperm isopropyl methylcethoxazine , threfen , nissylvadonone.
In general, according to the technical characteristics of microcapsule suspension processing, all oil-soluble active ingredients can be used as microcapsule suspensions. The current preparation process is divided into three types: the original polymerization method, the interface polymerization method and the phase separation method. The key equipment required in its processing process: emulsification pump (poor fineness, low efficiency) or emulsifier shearing machine (high efficiency, need to increase the tank, complex installation) or combination - emulsification, agitation, heating in one (saving investment, reducing production processes). Microcapsule suspension agent can prolong the residual effect, reduce the amount of organic solvent, improve the utilization rate of active ingredients, can make highly toxic pesticides low toxicity, and have excellent sustained release ability. Enterprises may refer to the suitable places for use of this dosage form described herein and the registered active ingredients to determine the microencapsule suspension products to be registered.