"How come there are a few more crow's feet at the corners of the eyes..."
"The nasolabial folds are getting worse again..."
"I'm old again..."
The first thing 26-year-old Xiaomei does every day when she gets up is to look in the mirror and see where her face has been left by the relentless years.
Xiaomei thought to herself: Is there anything that can make people not grow old?!
Immortality is the long-cherished wish of mankind for thousands of years, modern people anti-aging is mostly in the face of the "knife", but than the appearance, scientists want more "rejuvenation" in terms of physical function.
<h1>First, glutamine makes senescent cells "commit suicide"</h1>
Recently, in the journal Science, researchers at the University of Tokyo in Japan found that glutaminease 1 (GLS1) is a key target for the "rejuvenation" of the human body.
Glutaminease 1 can break down the ammonia produced by glutamine and neutralize the acidosis in senescent cells that could have killed cells, senescent cells are inhibited, and people's physiological functions and motor ability can be improved.
The study took 80-week-old mice as the subject, and the researchers used GLS1 inhibitors to eliminate senescent cells in the old mice.
The researchers found that after the implantation of GLS1, glomerulosclerosis, renal macrophage infiltration, and renal dysfunction were all improved due to age degradation. The two indicators of plasma creatinine and urea tend to normalize.
Like other drugs that clear senescent cells, GLS1 inhibitors can also improve lung fibrosis, liver macrophage infiltration, and serum albumin levels in older mice.
The researchers also found that in the process of cell aging, insoluble macromolecules in the lysosome can cause damage to the lysosomal membrane, when the hydrogen ions in the lysosome leak into the cell, there will be a decrease in intracellular PH, cell acidosis, and intracellular acidosis can lead to cell death.
By inhibiting the decomposition of glutamine, the intracellular acidosis of senescent cells cannot be improved, and senescent cells can die, and naturally normal cells can continue to function.
<h1>2. What is glutamine? </h1>
Many people may be unfamiliar with glutamine, but in fact, this substance is present in the human body and muscles.
As early as the 1950s, it was found to be an amino acid needed in many cell line culture processes and can be called a special nutrient that can help restore and maintain muscle mass.
In addition to helping build muscle, glutamine can also increase strength and improve endurance, glutamine has the potential to produce bases, can reduce the loss of exercise capacity and fatigue caused by acidic substances.
At the same time, glutamine is also an important raw material for the immune system, is a necessary product for lymphocyte secretion, proliferation and maintenance of function, it can be said that with its presence, immune cells can maintain activity.
<h1>Third, try to avoid the 5 bad habits of accelerating aging in life</h1>
Eat too many high-calorie foods: fried chicken, bread, cakes, crayfish and other high-calorie foods, although delicious, but also due to cooking methods and produce many harmful substances, including carcinogenic acrylamide. In addition, these foods are also easy to cause overweight and obesity, which damages tissues and functions and accelerates the aging of the body.
Sedentary non-exercise: Studies have confirmed that exercise can alleviate brain aging, and the longer the sedentary time, the faster it will age. The American Diabetes Association has also made it clear that all people should reduce their sedentary time, especially avoid sitting for more than 90 minutes.
Do not apply sunscreen: The aging of the skin is a natural law, but the external environment will also "help to abuse". The Massachusetts General Hospital in the United States has found that women who pay attention to sun protection have fewer wrinkles and age spots.
Smoking and alcoholism: Smoking and drinking alcohol will cause a decline in liver function, affect the stability of the internal environment, and accelerate the aging of the liver and the human body.
Staying up late: Staying up late will not only bring harm to the liver, kidneys and other organs, affect the metabolism and detoxification of the human body, cause the accumulation of toxins, and easily lead to endocrine disorders.
<h1>Fourth, 3 tips for anti-aging</h1>
When do people start to age? In fact, you can detect the 5 major signals that can be sent by the appearance, such as the hips become larger, the forehead becomes larger, the waist circumference becomes larger, the soles of the feet become larger, and the gap between the teeth becomes larger. Is there any way to slow down aging?
Exercise regularly: A study by Neurology found that exercise can slow down brain aging, up to 10 years younger. Research from Peking University Third Hospital also found that exercise can speed up blood circulation, increase oxygen and nutrients in the brain, and keep the mind active.
Mediterranean Diet, Eat Less Sugar: A Columbia University study found that people who followed the Mediterranean diet had a 5-year younger brain than those who followed the traditional diet. The Mediterranean diet is dominated by fruits and vegetables, whole grain cereals, legumes, and nuts.
In addition, studies have found that eating sweets will not only increase waist circumference, but also lead to premature aging of the human body and damage to the skin. Therefore, women who love beauty must reduce their intake of sugar.
Stick to sun protection: Ultraviolet rays can reach the dermis layer of the skin, destroying elastin fibers and collagen fibers and accelerating skin aging. The best way to protect against sun is physical sunscreen, that is, umbrellas, sunglasses, sunhats, must be used in case of large sun, you can also apply sunscreen in advance before going out.
The research that scientists have found that glutamine has anti-aging effects is worth celebrating, and in the future, more research is needed to confirm that they can also play an effective role in human aging. Before anti-aging through medical means, you may wish to try to fight aging through physical means, the cost is low, and the effect is not bad. #How far is cancer from you##Breeze Project##健康2021 #
Resources:
[1] < Science >: Let Senile Cells Commit Suicide! Scientists have found that senescent cells rely on glutamine to break down "life". Startnet.2021-02-01
[2] Four things in life are speeding up your aging! 》. Health Times.2016-05-16
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