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Yang Zhe, Department of Radiotherapy, Shandong Provincial Hospital: "Sniping" tumors for life

author:Qilu Evening News Network

Qilu Evening News Qilu One Point Reporter Qin Congcong Correspondent Lu Xiao

The fight against cancer is a war without smoke. In the face of the threat to the lives of patients brought by malignant tumors, Yang Zhe, deputy director of the Department of Tumor Radiotherapy of the Affiliated Provincial Hospital of Shandong First Medical University, held a "weapon" in his hand as a beam of "rays". Precise positioning, accurate planning, accurate illumination, he led the team to use this beam to carry the doctor's sincerity and warm "ray", the tumor is eliminated invisibly, so that tumor patients have the opportunity to regain the hope of survival and life.

Yang Zhe, Department of Radiotherapy, Shandong Provincial Hospital: "Sniping" tumors for life

Excellence

More precise radiotherapy is used in the clinic

As a major "weapon" against malignant tumors, radiation therapy is developing in the direction of precision radiotherapy. From university study to clinical work, Yang Zhe has experienced and witnessed its transformation from the beginning of two-dimensional illumination to today's three-dimensional stereotactic illumination.

Yang Zhe admits that radiation can kill cancer cells, but it may also damage non-cancerous normal tissues around the tumor. In the face of the cunning "enemy" of tumors with irregular appearance and internal heterogeneity, doctors must protect the safety of the surrounding "masses" while treating. In the era of traditional two-dimensional radiotherapy, a considerable number of patients cannot adhere to the end of radiotherapy due to serious side effects.

In 2005, with the help of solid oncology professional ability and exquisite radiation medicine technology, Yang Zhe took the lead in carrying out intensity-modulated radiotherapy (IMRT) technology in the provincial hospital, so that the shape of the irradiation field and the shape of the tumor target area were highly consistent in the three-dimensional direction, and the tumor area was irradiated at a non-uniform dose rate, achieving more accurate and less side effects of "three-dimensional" irradiation.

In 2018, Yang Zhe led the team to apply stereotactic ablation radiotherapy (SABR) to the clinic. This is currently the most advanced radiotherapy technology for body tumors, which uses the cone beam CT of the accelerator to monitor the position of the tumor, and focuses the high-energy rays from the three-dimensional direction to the tumor site, so that the tumor tissue is subjected to high-dose sculpted irradiation, and the tissue around the tumor is protected to the greatest extent, known for its good clinical efficacy and few side reactions. Up to now, the provincial hospital has completed more than 100 cases of SABR in patients, and the tumor volume of most patients has shrunk significantly within 1-2 months after radiotherapy.

Yang Zhe, who demands excellence, has never wanted to stop here. At present, he is leading his colleagues to tackle the new technology bigART of tumor radiotherapy under the guidance of bioinformatics, which is expected to fill the domestic gap.

The cave candle is faint

Do not let go of the clues of tumors

The Department of Radiation Oncology of The Provincial Hospital is located in a small white building on the east side of the south gate of the central hospital, and over the years, the size of the ward has been expanding, the number of patients has increased, and Yang Zhe's rigorous and meticulous work attitude has always been the same.

There was a patient who felt chest pain 5 years after lung cancer surgery, and no abnormalities were found after the local hospital review, which was treated as intercostal neuritis, but after a period of symptomatic treatment, chest pain was still often accompanied.

After getting the patient's medical records, Yang Zhe calmed down to compare them one by one. Finally, in the film compared before and after, an abnormality was found - the chest wall near the original lesion was thickened.

Although similar metastases are uncommon, they are not clinically infrequent. Soon, the results of the puncture confirmed Yang Zhe's inference that lung cancer had metastasized in the patient's chest wall.

Yang Zhe knows very well that a considerable number of tumor patients who come to the department have no chance of surgery or are not suitable for surgery, and when they seek medical treatment, they are already life-saving. In the face of these patients who are on the edge of life, as a doctor, you must make a diagnosis for them as quickly as possible. Behind those black and white images, there are complex truths about diseases, and only by finding those inconspicuous clues can we establish a "beacon" for clinical treatment.

In the expert clinic before the Mid-Autumn Festival, the patient appeared in front of Yang Zhe again. Thanks to the timely diagnosis and fine radiotherapy of that year, the metastatic tumor was controlled, so that he has lived safely for five years.

Behind a pair of "wise eyes", there are countless late-night ambushes. Nowadays, Yang Zhe combines radiotherapy with new anti-tumor methods, such as radiotherapy combined with targeted therapy, radiotherapy combined with immunotherapy, to standardize and personalize comprehensive treatment to maximize the interests of patients.

Yang Zhe, Department of Radiotherapy, Shandong Provincial Hospital: "Sniping" tumors for life

Be aware of it

He is an oncologist and a psychological mentor

The game between people and tumors is long and arduous. In the face of the "falling from the sky" of tumors and the front line of life and death, as a professional oncologist, he is not only good at opening the "life door" of patients with his professional strengths, but also uses patience and love to communicate to open the "heart door" of patients.

A lung cancer patient with a mutation in the ALK gene whose tumor has shrunk but no longer shrinks after taking targeted drugs for a period of time, and the patient wants to choose radiotherapy to consolidate the efficacy and prevent possible targeted drug resistance problems, but is particularly worried about the occurrence of side effects such as radiation pneumonia. Can I do radiation therapy? She found Yang Zhe with doubts.

"Radiation pneumonia is likely to occur, but even if it does, we can handle it very well." After comprehensive analysis, Yang Zhe's answer was very direct.

The old man's previous doubts, after hearing these words, turned into a crisp action - then do radiotherapy!

Yang Zhe said that many of the current means of treating malignant tumors will almost always bring certain adverse reactions, but they vary from person to person and to different degrees, and these problems require both patient understanding and rich clinical experience of doctors. The elderly really developed radiation pneumonitis after radiotherapy, but after a week of active treatment, their symptoms were significantly reduced and the pneumonia was effectively controlled.

Doctors have temperature, and medicine is warm. Trust is not accidental. Yang Zhe's professional judgment and sincere and patient attitude allow the old man's heart to settle down and fight against malignant tumors with a more positive attitude.

The list goes on and on. Seeing the heartfelt smile of patients when their symptoms are alleviated or cured, Yang Zhe will always be shrouded in professional happiness. His 25 years of practicing medicine may be just a flash in the long river of history, but it has ignited a glimmer and illuminated the way forward for countless tumor patients.

Yang Zhe, Department of Radiotherapy, Shandong Provincial Hospital: "Sniping" tumors for life

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