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On October 14, 2020, the 40th anniversary of the establishment of the Shenzhen Special Economic Zone was commended for 40 innovative and entrepreneurial figures and advanced model figures who bravely stood at the head of the tide of the times, were determined to reform and innovate, and dared to practice and explore, and there were two representatives in the field of health and health, of which Liu Lei, secretary of the party committee and president of the Third People's Hospital of Shenzhen, was one of them.
On September 8, he was also named an advanced individual in the national fight against the new crown pneumonia epidemic and an outstanding communist party member in the country. "In just over a month, I have been received by General Secretary Xi Jinping twice, and I feel very honored. This is my personal honor, and it is also the honor of all medical workers in Shenzhen. Liu Lei said.
He came to Shenzhen in 1997 and has been around for 24 years. Although the time is not very long, it has been built into the history of Shenzhen's development and health.

The First Battle
Create a Shenzhen highland for organ transplantation
Heading south to Shenzhen, Liu Lei's first stop is Shenzhen Children's Hospital. After 19 years of deep cultivation here, he single-handedly created pediatric surgery as a discipline leader, created pediatric abdominal surgery and neonatal surgery, and gradually grew from a clinical expert to a scholar-type hospital administrator.
The Shenzhen Third Courtyard is the second stop and the terminus of his heart. What is recorded here is more that he has been working in the three hospitals for more than 5 years, and the happiest thing is to win the three major battles." ”
The first battle took place in the field of organ transplantation.
As one of the largest medical innovations of the 20th century, organ transplantation sits at the top of the pyramid and represents the combined level of a region's medical service capacity. Shenzhen has explored the field of organ donation and transplantation very early, in 2003 promulgated the earliest local human organ donation and transplantation regulations in the country, and since 2007, some hospitals have become national and provincial pilot units.
However, in early 2016, Chen Zhu, then vice chairman of the Standing Committee of the National People's Congress, came to investigate, and a Red Cross expert said that no hospital in Shenzhen had been able to perform organ transplants, and the pilot did not meet expectations. Chen Zhu and the accompanying leaders of the municipal party committee were surprised.
This has aroused the competitive spirit of Shenzhen people, building a medical and health highland that meets the requirements of economic development, we must make up for this shortcoming as soon as possible, who can take on the big responsibility? Luo Lexuan, then director of the Municipal Health Commission, recommended Liu Lei.
After receiving the notice, Liu Lei was a little surprised. This is not the first time he has undertaken an epoch-making project for Shenzhen - after Shenzhen decided to invest 5 billion yuan to expand the construction of the Shenzhen Third Hospital, he is still the party secretary of Shenzhen Children's Hospital, and he will take the three hospitals with him to set off again.
"The children's hospital is in the city center and is conveniently located within ten minutes of work. The new courtyard of the three hospitals was in Longgang, which was still a suburb at that time, and it would take a lot of time on the road, so I didn't want to go. Liu Lei admitted that he had hesitated. But he never lacked the responsibility of starting a business, and soon put on the battle. Soon after he arrived at his post, party building, contingent building, and cultural construction were in full swing, and suddenly he wanted to go to the horse organ transplantation work. Once again, the drums beat in his heart.
In fact, the first choice is another hospital, which encountered greater resistance and chose Liu Lei. This detail actually aroused his fighting spirit, and took over this hot potato that many people avoided. He believes that as a specialized hospital for the prevention and treatment of infectious diseases, the three hospitals that are deeply involved in the field of liver disease have a basis for liver and kidney transplantation.
When the first blow came from an unexpected place. "I went back to do a study and found that it was broken, and it was an impossible task!" Liu Lei said that organ transplantation requirements must have the qualifications of the top three hospitals, and the shenzhen third hospital was not yet at that time. The results of further grooming made him even more devastated, "We don't even have the surgical instruments needed for organ transplantation, this is not starting from scratch, it's simply starting from negative numbers." ”
The words still seem to carry the original resignation, but the tone is already the victor's feeling of looking back on the past.
Liu Lei loved to watch war movies since he was a child, and when he was a child, he went to live in the mountains of Hunan and Guizhou with his parents who worked under the Ministry of Water Resources, and developed the courage to dare to struggle with heaven and earth. From the very beginning, he did not plan to follow the steps, but multi-line operation, while starting the top three evaluation, while preparing the organ transplant team, while contacting the top domestic Sun Yat-sen University Affiliated First Hospital Professor He Xiaoshun team and Zhejiang University Medical College Affiliated First Hospital Zheng Shusen Academician Team, to seek flexible cooperation, introduce their wisdom, and cultivate their talents.
The "three projects" launched by the Shenzhen health system in 2014 have given Liu Lei great support with a large investment. Not long after, the organ transplant center was established, and on April 22, 2016, the Shenzhen branch of the organ transplant center of zhongshan first hospital was listed; on May 17, the shenzhen branch of the liver transplant center of the first hospital of Zhejiang University was listed.
During this period, with the help of various departments of the hospital, the organ transplant department also completed the construction of the whole chain from surgery, ICU, anesthesia, examination, imaging to postoperative follow-up in the shortest possible time.
This is clearly a masterpiece of Shenzhen's speed. Even 13 days after the cooperation with the team of Zhongshan First Hospital, under the guidance of the hospital's OPO (organ coordinator), the new team formed by Liu Lei carried out the first organ donation operation, and one patient donated liver, two kidneys and corneas of both eyes.
▲The medical team of the Shenzhen Third Hospital is undergoing organ transplantation
But the most important thing is the qualification approval. "In this matter, I would like to give special thanks to Minister Huang and Secretary Xu, who are noble people of the Shenzhen Third People's Court." Liu Lei said. The former is huang Jiefu, the former minister of health, one of the key designers of China's organ transplant system, and has guided Liu Lei in terms of approval process and material preparation. The latter was Xu Qin, then secretary of the Shenzhen Municipal Party Committee, who personally wrote a letter to Beijing to introduce the construction of the health field in Shenzhen and the health needs of the masses, which played a huge role.
The Municipal Health Commission has also provided great help. Liu Lei drafted the application materials, and after handing them over to the committee, Luo Lexuan put down other work and deliberated them word by word to ensure that the materials were convincing enough.
In 2017, Liu Lei sounded the charge of two high-intensity battles in a row, first overcoming difficulties, obtaining liver and kidney transplant qualifications, opening up Shenzhen's own organ transplantation position, and soon successfully creating a top three hospital.
"On the night of obtaining the organ transplant qualification, Director Luo Lexuan and I talked on the phone for more than half an hour, and I still remember it happily." Liu Lei said. The Department of Organ Transplantation has also been approved as a key discipline of municipal medicine, and a variety of surgical methods such as improved camel liver transplantation, non-diversion in situ classic liver transplantation, split liver transplantation, pediatric liver transplantation, and reduced volume liver transplantation have been gradually carried out, and the success rate of surgery has been raised to the leading level in China.
In 2020, despite the impact of the epidemic, the liver transplant team completed a total of 121 liver transplants, ranking 16th in the country and 3rd in the province. "It marks our entry into the first phalanx in the country." Jiang Nan, the leader of the liver transplantation department, said that not long ago, he and his team received the 1 million yuan "Dean Award" issued by Liu Lei.
This reward began with an agreement when Jiang Nan joined the company. He originally worked in Guangzhou, engaged in hepatobiliary pancreatic and spleen surgery and liver and pancreatic transplantation clinical and research for many years, and went to the affiliated hospital of the University of Western Ontario in The World-renowned Organ Transplant Center. After learning that the organ transplant department of the Shenzhen Third Hospital was opened, in order to seek greater development space, he found Liu Lei to introduce himself.
Liu Lei was very proud of this introduction. Jiang Nan brought the team and two National Natural Science Foundation projects as a "dowry", under his leadership, the organ transplant team of the Shenzhen Third Hospital bid farewell to the pioneering era, entered the harvest period, and also created a number of records, such as the implementation of the world's first liver transplant of poisoned fungus poisoning patients, the oldest age (76 years old) liver transplantation in Guangdong Province, the largest volume of liver cancer liver transplantation in Guangdong Province and other high-difficulty liver transplantation.
It is worth mentioning the first case of AIDS cross-blood type liver transplantation in China. AIDS patients have immunodeficiency, cross-blood type transplantation makes the immune system more fragile, and the patient also has multiple organ failure and dysfunction. Before the operation, Jiang Nan couldn't sleep soundly for two consecutive days, "My head was like a movie, demonstrating all the links over and over again, lest there be a half-point difference pool." As a surgical expert, Liu Lei is also very concerned, and has organized expert discussions many times to predict possible situations and formulate plans. In the end, the operation was very successful and caused a national sensation.
"This difficult and complex operation reflects the improvement of our organ transplantation level, and also reflects the improvement of the comprehensive treatment level and the ability to treat critical care." I am looking forward to organ transplantation, and I hope that in about 3 years, I will achieve the top 5 in the country. Liu Lei said. At the same time, as a deputy to the Municipal People's Congress, he began to think about more far-reaching issues, "hoping to explore the Shenzhen model of organ donation and transplantation that can be copied and promoted through legislation and other means." ”
Second Battle
Building a "national team" for the prevention and control of infectious diseases
In just a few years, Longgang District has moved from barren to prosperous, and the three courtyards of Shenzhen are still landmarks.
Standing at the main entrance of Bulan Road, look inside, there are 3 large signboards on the towering building in the courtyard. The front outpatient building is the real name "Shenzhen Third People's Hospital", the longest in the middle is the "Second Affiliated Hospital of Southern University of Science and Technology" marked with its teaching hospital identity, and the top of the tallest building is the most eye-catching "National Clinical Research Center for Infectious Diseases".
This national title is the result of the Second Battle of the Shenzhen Third People's Court.
▲Shenzhen Third Hospital
As a national science and technology innovation base jointly built by the Ministry of Science and Technology, the National Health Commission, the State Food and Drug Administration and the General Logistics Department of the Chinese People's Liberation Army, facing the needs of national disease prevention and treatment, taking clinical application as the guide, taking medical institutions as the main body, and supporting the collaborative network, to carry out clinical research, collaborative innovation, academic exchanges, talent training, achievement transformation, popularization and application of technological innovation and achievement transformation, the National Clinical Medical Research Center has a very high gold content. Before 2017, 32 units were built in 3 batches in 11 disease areas such as cardiovascular disease, nervous system disease, chronic kidney disease, and malignant tumors. There are two in Guangdong, namely the National Clinical Research Center for Chronic Kidney Diseases in Nanfang Hospital of Southern Medical University and the National Clinical Research Center for Respiratory Diseases of the First Affiliated Hospital of Guangzhou Medical University.
When preparing for the fourth batch, the National Health Commission included infectious diseases in the scope of construction, including tuberculosis – due to factors such as drug resistance, tuberculosis, which was once silent, has become an important infectious disease that threatens human health and safety. The World Health Organization proposed to end the tuberculosis epidemic by 2035, which is a difficult task for China, and the establishment of the National Tuberculosis Clinical Medical Research Center is to explore a new way to prevent and treat.
The Provincial Health Commission has selected 9 medical institutions to strive for in a targeted manner, of which the task of tackling the tough problems in the field of infectious diseases has been given to the Shenzhen Third Hospital and the Provincial Tuberculosis Control Center, with the three hospitals as the main body. "The Shenzhen Municipal Party Committee and the Shenzhen Municipal Government attach great importance to it and made an important decision to declare the National Clinical Medical Research Center in 2017." Liu Lei recalled. Commissioned by the Ministry of Science and Technology, the China Biotechnology Development Center went to Shenzhen to conduct a thorough investigation and believed that only the Shenzhen Third Academy "has a little possibility".
"At that time, our slogan was to guarantee 1 to compete for 3, and the three houses ranked 9th, which looked like a number." Liu Lei joked. He has repeatedly expressed his intention to achieve overtaking in curves. There are also different voices, saying that overtaking in curves violates traffic rules, "You enter the final is victory." ”
Liu Lei's mother is a factory doctor, although he has heard about it since he was a child, his dream when he was young was to be an engineering man. It was not until 1978, when I took the college entrance examination, that I was persuaded by my teachers and family to enter medical school. He studied for a doctorate from academician Zhang Jinzhe and graduated in 1994, which is one of only 7 doctorates in pediatric surgery in the country. Later, I went all the way from Zunyi to Changsha and then to Shenzhen. 2018 is his 40th year in the field of medicine, and he personally created a "national team", which may be a good gift.
He won the support of the Provincial Health Commission, the Provincial Department of Science and Technology and the Municipal Party Committee and Municipal Government, and the tuberculosis prevention and control resources in the province were tilted towards the three hospitals. "Bringing the province's high-quality resources into a hospital has never been seen before in the history of infectious disease prevention and control in Shenzhen." He said that there is no reason to do one thing with the strength of the whole province without a fight.
He also invited a group of top experts at home and abroad to carry out top-level design, and jointly declared with more than 100 companies and institutions such as Ping An, Tencent, BGI, Huawei, ZTE, etc., to build a win-win situation.
The hospital set up a special team, and Liu Lei personally led the team to enter the "white plus black" and "5 + 2" work mode 10 months in advance. According to statistics, from October 2017 to August 2018, the group cursor book changed 55 versions, the defense PPT changed 86 versions, often in order to modify a sentence of expression, a detail up to the night, including many wisdom from experts in Guangzhou and other places.
The final defense was made on 27 August 2018. Liu Lei took the stage with his head held high and talked nonchalantly. In the previous rounds of defense, he entrusted others, just like he usually played basketball, and the last level was a calm shot, pressing the whistle for three points!
"At that time we had two opponents, one from Beijing and one from Shanghai, and we were strong. Beijing talks about the past, Shanghai talks about the present, and we talk about the future. Liu Lei said. He also introduced the advantages of the special economic zone's institutional mechanism, the environment and concept of innovative development, "In the next step, Shenzhen will explore the integration of tuberculosis medical prevention and control, especially the extensive participation of the whole society to form a three-dimensional prevention and control mechanism." ”
The whole audience was intoxicated by the words. Shenzhen was originally a small fishing village, and with its imagination and dedication to the future, it has created a miracle of urban development. Perhaps the judges believe that if given a chance, the shenzhen three hospitals can write a legend of hospital construction. On May 24, 2019, the good news was officially announced: the Shenzhen Third Hospital was approved to become the first national clinical medical research center in Shenzhen, the only national clinical medical research center for tuberculosis in the country, and the only prefecture-level hospital among the 18 units.
"It was a pole vault and we won." Liu Lei was so happy that he stayed up all night. One leader quipped: "The regular army has fallen, and the guerrillas have the last laugh." ”
▲The defense site of the National Clinical Medical Research Center for Infectious Diseases
Relying on Guangdong and Shenzhen, the three hospitals have long been no longer guerrillas, but a tertiary first-class research hospital integrating medical treatment, scientific research and teaching, featuring infectious disease specialties. Tuberculosis disciplines and infectious diseases are ranked No. 1 in Guangdong Province, the Lung Disease Medical Center ranked No. 3 in tuberculosis in the 2019 China Hospital Science and Technology Influence Rankings, and the Liver Disease Center is the only key specialty of liver disease in Shenzhen. The hospital also has the first top-level composite operating room in Shenzhen, equipped with the fourth generation of Da Vinci robots, the first intelligent integrated laboratory in China, and a hospital fire-eye system with high automation of the whole process.
Third Battle
From the battlefield of the fight against the epidemic to the far side
On January 2, 2019, shortly after winning the second battle, Guangdong Province announced the list of the second batch of high-level hospitals in the first phase, and the shenzhen three hospitals were successfully selected as the only infectious disease prevention and treatment hospital in the first phase.
Duan Yufei, director of the Provincial Health Commission, once stressed that the implementation of high-level hospital construction is an important measure for Guangdong to benchmark the international and domestic advanced level, promote the construction of a number of domestic first-class and world-leading hospitals, effectively solve the problem of unbalanced and uncoordinated medical and health development, and achieve a significant improvement in the overall medical service level of the province. Obviously, in the construction of Guangdong's "top of the sky and the ground" medical and health pattern, the three hospitals are an important link.
When the list was announced, many people were skeptical and asked whether the Shenzhen Third Hospital, which was only established in 1985, was worthy of the label of a high-level hospital. A year later, the outbreak of the new crown epidemic gave the answer.
"We've been working on a salary for 5 years, and it seems like a lot of work is for this epidemic." Liu Lei said. In the face of the menacing new crown pneumonia, he led the shenzhen three hospitals to fully demonstrate the responsibilities and strength that the national team and high-level hospitals should have, as the only designated treatment hospital in Shenzhen, it has made great contributions in the fields of patient treatment, epidemic prevention and control and scientific research.
▲ Wu Yihuan, former vice mayor of Shenzhen (front row, first from the left), investigated the emergency hospital of the three hospitals in Shenzhen
This is already one of the well-known stories of 2020. "At the beginning of the epidemic, patients flocked to the epidemic, support was not in place, and they did not understand the condition, so the pressure was great." Liu Lei said. When the pressure was at its greatest, nearly one-third of the new crown patients in the province were in the three hospitals, and he was thinking all the time, "Whether this patient can be saved, what this place needs to pay attention to, whether this angle can carry out research..." (Wonderful report→ Liu Lei: We have fought hard for Shenzhen)
Having experienced the battle against SARS and other public health diseases such as avian influenza, the Shenzhen Three Hospitals have sufficient combat experience. As the main backbone, Liu Lei has always been very calm. Influenced by him, everyone calmly coped. During the investigation of the World Health Organization, it was particularly praised: "The response is timely, the medical technology is good, the equipment is good, and the hospital sense is also doing well." ”
On May 21, 2020, the last confirmed patient of the three hospitals was discharged from the hospital. A total of 462 confirmed cases were admitted and treated, with a cure rate of 99.35%. At the same time, Liu Lei also organized scientific research, obtained 47 projects at the provincial and ministerial levels and above, with a cumulative funding amount of more than 46 million yuan, published 110 SCI papers in top international journals as the first or corresponding author, with an impact factor of more than 848 points, and applied for 5 international patents and 5 domestic patents.
▲Liu Lei was awarded the national advanced individual in the fight against the new crown pneumonia epidemic
Today, the scientific research related to the epidemic is still continuing, and experts such as Academician Zhong Nanshan are involved. "We have only one purpose, to understand this disease as soon as possible, so that mankind can defeat the new crown as soon as possible." Liu Lei said. Not long ago, Guangdong Province announced the list of winners of the 2020 Guangdong Science and Technology Award, led by Academician Zhong Nanshan, and the project of "Prevention and Control Strategy and Clinical Diagnosis and Treatment of Emerging Coronavirus Infection" of the Shenzhen Third Hospital as the second completed unit won the special prize of the Science and Technology Progress Award, and the winners included Liu Lei and 7 experts from the three hospitals.
At the beginning of this year, the state also reaffirmed the construction achievements of the Shenzhen Third Hospital from another perspective - on January 21, 2021, the National Health Commission issued a circular praising the advanced models of improving medical services in 2018-2020. The Shenzhen Third Hospital's "Switch" Management Model and Practice Based on the Combination of "Epidemic Suppression" was selected as a typical list in the initiative of "focusing on critical and severe diseases and innovating emergency emergency services".
The three hospitals that adhere to the principle of "strong specialty and great synthesis" have long been reborn. A comprehensive development strategy with the construction of the National Tuberculosis Clinical Medical Research Center as the core, the construction of the National Clinical Key Specialties and Organ Transplantation Disciplines of Infectious Diseases as the two wings, the emerging infectious diseases and incurable infectious diseases, liver diseases and AIDS as the pillars, and the eight comprehensive specialties as the support is taking shape. Liu Lei called it "one body, two wings, four-wheel drive, and eight major supports."
In contrast, Liu Lei still works in an office of less than 10 square meters, which is filled with various documents and honorary certificates, as well as fruits to replenish energy during overtime. Tall and tall, he sat behind his desk and looked a little cramped, but the plaque on the wall quietly expressed the owner's voice: spoiled.
Although the dwelling is small, the pattern is large. There are leaders to investigate, or media interviews, Liu Lei will take them to the conference room at the top of the National Clinical Medical Research Center for Infectious Diseases when he rises, walk up to the balcony, and look into the distance, where there is the second phase of the construction project, the emergency hospital area of 1008 negative pressure wards has been put into use, and it is in full swing; the new organ transplant building is pouring foundations, and it is like fire.
"The past years are all prologues; every bit of effort is painstaking effort." Liu Lei said. Further along with his gaze, you can see the Xiamen-Shenzhen Railway covered with greenery, and a Fuxing train roaring forward.
Lead Writer | Song Bingjun
Edit | Fang Yang Su Haining edited | Zhang Xiuli
Source | This article was published in the magazine "The Beginning of Man" and may not be reproduced without authorization
Produced by Guangdong Health Online All Media Team