The symptoms of myelodysplastic syndrome (MDS) are generally very secretive, with nearly half of patients having no obvious clinical symptoms or some symptoms unrelated to blood diseases, while the other half's symptoms depend on the severity of anemia, platelet and leukopenia, and progression, while common symptoms are as follows:
1. Anemia: most patients with myelodysplastic syndrome begin with anemia, and anemia symptoms may last for months or even years.
2. Bleeding: about 20% to 60% of patients will have a tendency to bleed during the course of the disease, but the degree of bleeding varies, most bleeding patients have mild bleeding, manifested as petechiae or ecchymoses on the skin, nosebleeds or bleeding gums, etc., but there are also a very small number of patients with severe bleeding symptoms, and gastrointestinal bleeding or even cerebral hemorrhage may occur. This bleeding may be related to thrombocytopenia, to platelet dysfunction, or to both.
3. Fever: about half of patients will have fever symptoms during the course of the disease, which is often related to infection, most of them are low to moderate fever, a few will have high fever, the infection is mainly respiratory infections, and other infections are fewer.
4. Lymphadenopathy: about one-third of patients will have symptoms of lymphadenopathy, generally mild symptoms, and it will not be painful to touch.
5. Other symptoms: like some dizziness, fatigue, weakness and other symptoms, about 80% of patients will appear, and some patients may have nausea, epigastric discomfort, weight loss, joint pain and other symptoms.