Roma, which was ranked 5th in Serie A before the game, ushered in the first leg of the Europa League semi-finals led by Italian legend De Rossi, and the Roma team sat at their home stadium against the new Bundesliga champion Bayer Leverkusen led by Spanish legend Alonso.
Roma were unbeaten in two games in a row in all competitions (beating Udinese and then drawing with Napoli), while Bayer Leverkusen were winless in three games in a row (three draws) before the game, although Bayer Leverkusen remained unbeaten for the season. In the last three meetings between the two sides, Roma won 2 and drew 1, and Bayer Leverkusen was in the upper hand, but before the game, more than 60% of fans believed that the visiting Bayer Leverkusen team could beat Roma.
In the 29th minute, Karlsdorp made a mistake in the return pass, and the Spanish international Grimaldo followed up on the left side of the penalty area to send an inverted triangle pass, and the German international Wirtz, who is worth 110 million, followed up to meet the ball near 12 yards and shot low into the bottom right corner of the goal to help the visiting Bayer Leverkusen team take the lead.
In the 74th minute, Stanišić returned the ball, and German international Andrich blasted a super long arc world wave to help Bayer Leverkusen extend their lead.
In the end, the visiting Bayer Leverkusen team beat Roma as they wished, and took the lead.