There are thousands of famous prescriptions of ancient and modern Chinese medicine, in addition to the top ten prescriptions of traditional Chinese medicine, if other famous prescriptions are ranked, it may be that Fengtong Shengsan and Wujisan will be on the list. This is because the use of the two good prescriptions of Fengtong Shengsan and Wujisan is so wonderful that many doctors have praised them, and they are also equipped with a slogan, such as "If you are sick or not, you will be able to prevent Fengtong Sheng", and "A song of Wujisan, the house does not shout under the house". For modern people, everyone may be more familiar with Fengtong Shengsan, but they are relatively unfamiliar with Wujisan. However, what many people don't know is that Wujisan is actually longer than the medicinal history of Fengtong Shengsan, and it is a proper prescription for the ages.
However, it is unbelievable that for a long time, the textbooks of prescription science did not include Wujisan, but despite this, Wujisan is too outstanding in strength, like the power of seeds, whether it is the heat of the desert, or the cold of the snow-capped mountains, or the low oxygen of the swamps, or the tenacity of the rocks, as long as there are seeds, there is life waiting to bloom. After all, as a famous prescription for the ages, Wujisan's good clinical effect is really "inherently beautiful and difficult to give up". However, as for the source of Wujisan, it is generally believed that it comes from the official prescription book of the Song Dynasty "Taiping Huimin and Pharmacy Bureau", but after literature research, it is found that the "Secret Recipe for Immortal Conferral of Injury Continuation" by Lin Daoren in the Tang Dynasty may be because the "Taiping Huimin and Pharmacy Formula" is more detailed, so later generations mostly use this book [1].
According to the records of the Taiping Huimin and Pharmacy Bureau, the whole recipe consists of "Angelica dahurica, Chuanxiong, licorice (boiled), Poria cocos (peeled), angelica (to remove reed), cinnamon (to remove coarse skin), peony, and banxia (to be washed seven times), tangerine peel (to white), citrus aurantium (to be boiled, fried), ephedra (to remove roots, knots) 6 taels each, Atractylodes atractylodes (soaked in rice swill) 4 taels, dried ginger (爁) 4 taels, bellflower (to remove reeds) 12 taels, magnolia bark (to remove coarse skin) 4 taels" Composed of 15 flavors of traditional Chinese medicine, the specific method of use is to first finely chop the rest of the Chinese medicine except for the two flavors of citrus aurantium and cinnamon, fry it over slow fire to change color, and then spread it cold, and then put the citrus aurantium and cinnamon into it after grinding, mix evenly, each time you take it, take three coins at the end of the medicine (that is, 9~10 grams in modern times), use a cup of water, add three slices of ginger, fry half of it, and take it while it is hot. In addition to citrus aurantium, cinnamon, angelica and tangerine peel, the rest of the traditional Chinese medicine is fried, and then fried with the same after being cold, which is called "clinker Wujisan", and the main treatment is to disperse the cold and evil;
According to the records of the Bureau, Ye Juquan divided the efficacy of Wujisan into four major sections, the first is to regulate the central and smooth qi, remove wind and cold, and dissolve phlegm drink; the second is to treat the spleen and stomach with cold, flank distension and pain, chest and diaphragm phlegm, vomiting and nausea; the third is external wind and cold, internal injury and cold, heart and abdomen are stuffy, head is dizzy, shoulder and back are anxious; limb laziness, cold and hot exchanges, and lack of food and drink; the fourth is the woman's blood and qi imbalance, pain in the heart and abdomen, uneven menstruation, or amenorrhea, dystocia and fetal stillbirth[2]. The "Bureau" also records the addition and subtraction of the five accumulations and dispersions, such as the cold air rushing, heart, flank, umbilicus, abdominal distension and tingling, nausea and vomiting, excretion and clear grain, and phlegm, bladder and small intestine pain, add three slices of simmered ginger, a little salt, and fry together; Seven grains of soy bean, fried together; For example, if you feel cold, or your body is not very hot, your limbs are anxious, or your hands and feet are cold, add seven fried dogwoods, a little salt, and fry them together; for example, if the cold and heat are unbalanced, cough and wheezing, increase the jujubes, and fry them together; for example, if a woman has a difficult birth, add vinegar and fry them together.
For the indications of the five accumulations, Ye Juquan made a 7-point summary, the first point is the stagnation of the stomach, cold drinking, lodging and food, stomach pain, or vomiting, abdominal distention, or stomach vibrating sound, waist and knee cold; the second is abdominal cramp and acute pain, hernia rush, or cold air attack, vomiting, unable to eat and drink, hot at the top and cold at the bottom, or cold limbs; the third is the woman's blood and qi irregularity, menstrual irregularity, or dysmenorrhea, under the leucorrhoea, cold pain below the waist, and slow pulse; the fourth is the woman with dystocia, or stillbirth, or undressed, abdominal pain, lochia, accompanied by cold syndrome, The fifth is cough and wheezing, palpitations and urgency, chest pain and congestion, phlegm and saliva congestion in the throat, accompanied by shoulder, back and arm pain, waist and femur cramps, and a strong pulse; the sixth is wind, cold, dampness, musculoskeletal pain, bruises, cold pain in the lower back, beriberi, pain in the feet and knees, hernia and cold pain in the abdomen, or onset of cold in the cold, cold feeling in the waist and feet; the seventh is cold, wind chill, chills, headache, no fever, body pain, chest tightness, cough and qi reversal, or abdominal pain, and the pulse is solid and no sweat [2].
As the famous Qing Dynasty physician Wang Ang said, "Wujisan cures all kinds of accumulations", that is, it can treat all kinds of accumulation diseases, and in detail, the real core of Wujisan is that it can sweep away the stagnation of cold poison, food poison, gas poison, blood poison, phlegm poison, and other stagnation, as well as the toxins produced by stagnation. In general, it ranges from the accumulation of chancre caused by overeating and improper diet in children, to the accumulation of uterine fibroids caused by cold and dampness in adults, and even tumors, cysts, and other types of masses [3]. It is conceivable that such an eternal prescription as Wujisan is an unfathomable existence. So, how do the Chinese medicines of Wujisan sweep away the five accumulations? All of them are compatible with good medicines, among which ephedra and angelica can dispel cold on the surface; dried ginger and cinnamon can dispel cold in warmth; the combination of these four flavors of Chinese medicine can remove cold accumulation; Atractylodes atractylodes and magnolia officinalis can dispel dampness; banxia, tangerine peel, poria cocos, and licorice can remove phlegm accumulation; angelica, Chuanxiong, and peony can dissolve blood accumulation; and bellflower and citrus aurantium can dissipate qi accumulation. That is to say, when all medicines are combined, all accumulations are eliminated.
On the surface, Wujisan is a 15-flavor Chinese medicine, but with the ginger in the decoction method, it is actually a 16-flavor Chinese medicine. Since it has been absent from several editions of Formulary, it has not been studied in sufficient depth. For the compatibility of Wujisan's monarchs and ministers, Ye Juquan believes that Wujisan uses Atractylodes atractylodes as the king's medicine, Platycodon as the subordinate medicine, ephedra, citrus aurantium, tangerine peel, etc. as adjuvants, and the rest as the medicine [2]. However, Professor Li Fei et al. believe that Wujisan should be composed of ephedra, angelica, dry ginger, and cinnamon as the main components of the formula, and the combination of Atractylodes atractylodes and Magnolia officinalis to remove dampness, Banxia, tangerine peel, Poria cocos, and licorice to eliminate phlegm accumulation, Angelica sinensis, Chuanxiong, and peony to dissolve blood accumulation, Platycodon and Citrus aurantium to accumulate qi, and boiled licorice to neutralize and reconcile various medicines, and these traditional Chinese medicines are auxiliary parts of this prescription [4]. However, in terms of the compatibility of the prescription, the whole recipe should be based on the 5 flavors of Chinese medicine such as Atractylodes, Ephedra, Angelica Angelica, Ginger and Cinnamon, the 7 flavors of Magnolia officinalis, tangerine peel, Banxia, Poria cocos, Angelica, Paeonia and Chuanxiong as the subordinate medicine, the 3 flavors of bellflower, citrus aurantium and ginger as the adjuvants, and the 1 flavor of licorice as the medicine.
Wujisan is the same as Fengtong Shengsan, which is messy and messy at a rough look, and wonderful when you look closely, this is completely a classic recipe for "pretending to be a pig and eating a tiger", if you don't have a pair of discerning eyes, it is very likely that you will miss such a classic miracle remedy. For the compatibility mystery contained in Wujisan, as Ye Juquan said, Wujisan seems to have a complicated taste of medicine, but the efficacy of traditional Chinese medicine compound prescriptions cannot be seen in isolation from each drug The efficacy of Wujisan contains Atractylodes, Magnolia officinalis, tangerine peel, licorice, which is a flat stomach powder for transporting spleen and dampness; Licorice is the main treatment of all phlegm drink Erchen soup; there is also the Guizhi soup that treats the sun manifestation; there is also the Ling Guishu sweet soup that treats phlegm drinking; there is also the Ling ginger sweet soup that treats kidney disease; there are four things to remove the rehmannia, which has the function of passing the blood through the meridians; there are also ephedra and cinnamon branches Xinwen published to dissipate the cold; in addition, the dry ginger, cinnamon, citrus aurantium, and magnolia officinalis are used to promote qi stagnation; tangerine peel, Banxia Heephedra, and bellflower open the lungs to expel phlegm; hemp cinnamon, dry ginger, Chuanxiong, angelica, Licorice has the meaning of life-sustaining soup, and throughout the whole formula, the structure is tight, and it is actually a compound formula of the above famous recipes [2].
Modern pharmacological studies have shown that Wujisan has pharmacological effects such as anti-infection, antiviral, cytoprotective, gastrointestinal motility [1], antipyretic, anti-inflammatory, cough suppressant, expectorant, immunomodulatory, and diaphoresis [5]. The modern clinical application of Wujisan is also quite extensive, not only for the treatment of external cold, internal injury diet, low back pain, neck stiffness, chest and abdominal fullness, nausea and vomiting, general wandering pain, menstrual irregularities, uterine fibroids, pelvic effusion, cold and dampness pain and other diseases[3], but also can be used for cold and damp low back pain, postherpetic neuralgia, chronic abdominal pain, sciatica, wheezing and cough, stomach pain, dysmenorrhea, amenorrhea, chronic pelvic inflammatory disease and other cold evil patients, in addition to the cold and damp zone of women, as well as crane knee wind caused by wind cold and dampness, Diseases such as infusion also have certain curative effects [4]. Some doctors have concluded that Wujisan can be widely used in the treatment of internal and external gynecology and pediatric diseases, such as the treatment of external wind cold, cold and dampness and paralysis, wind cold cough and asthma, wind cold and dampness, External cold and lodging, acute gastroenteritis, rheumatoid arthritis, coronary heart disease, edema, acute nephritis, high fever, pyoent ear (otitis media), gout, head, body, limbs, lower back and leg pain, post-traumatic headache and dizziness, old rib fractures, blood in the urine after injury, bone hyperplasia, frozen shoulder, delayed healing of fractures, frozen shoulder, herpes zoster, postpartum fever, chronic pelvic inflammatory disease, dysmenorrhea, eczema, infertility, lochia, postpartum abdominal pain, postpartum stroke, pediatric urticaria [5] and other diseases.
It has to be said that Wujisan can be described as "supernatural", which can not only sweep away various accumulation diseases such as cold poison, food poison, gas poison, blood poison, phlegm poison, etc., but also can be widely used in various diseases such as internal and external women and children. But at present, there are two regrettable points, one is that the research on it in modern pharmacology can be called a dragonfly water, if you look at it from the perspective of Wujisan dismantling prescription, the pharmacological effect of the whole prescription should be very amazing, but the current pharmacological research is obviously too thin, especially Wujisan should be in analgesia, weight loss, anti-tumor, etc., there is no in-depth research; Of course, there are indications and contraindications for any prescription, and there are two points that need to be paid attention to for Wujisan, one is that the body is suffering from yin deficiency or damp heat, and it is not suitable for pregnant women.
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[2] Ye Juquan.My experience and experience of Wujisan[J].Journal of Traditional Chinese Medicine,1964,(6):33-35.
[3] HE Tianyou.A brief analysis of the clinical application of Wujisan[J].Northern Pharmaceutical Sciences,2015,12(4):52.)
[4] Li Fei.Traditional Chinese Medicine Advanced Series ·Prescription (2nd Edition)[M].Beijing:People's Medical Publishing House,2011.
Journal of Hunan University of Traditional Chinese Medicine,2009,29(5):75-77.
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